Chemotaxis-driven assembly of endothelial barrier in a tumor-on-a-chip platform

3D cardiac μtissues within a microfluidic device with real-time contractile stress readout

(2016) Aereas Aung et al.   LAB ON A CHIP

Endothelial Thermotolerance Impairs Nanoparticle Transport in Tumors

(2015) A. F. Bagley et al.   CANCER RESEARCH

Matrix stiffness drives epithelial–mesenchymal transition and tumour metastasis through a TWIST1–G3BP2 mechanotransduction pathway

(2015) Spencer C. Wei et al.   NATURE CELL BIOLOGY

Obesity-dependent changes in interstitial ECM mechanics promote breast tumorigenesis

(2015) Bo Ri Seo et al.   Science Translational Medicine

Embedded 3D Photopatterning of Hydrogels with Diverse and Complex Architectures for Tissue Engineering and Disease Models

(2015) Shruti Krishna Davey et al.   TISSUE ENGINEERING PART C-METHODS

Generation of Multicellular Tumor Spheroids with Microwell-Based Agarose Scaffolds for Drug Testing

(2015) Xue Gong et al.   PLoS One

Mineralized gelatin methacrylate-based matrices induce osteogenic differentiation of human induced pluripotent stem cells

(2014) Heemin Kang et al.   Acta Biomaterialia

Gelatine methacrylamide-based hydrogels: An alternative three-dimensional cancer cell culture system

(2014) Elke Kaemmerer et al.   Acta Biomaterialia

A microfluidic 3D in vitro model for specificity of breast cancer metastasis to bone

(2014) Simone Bersini et al.   BIOMATERIALS

A three-dimensional in vitro model of tumor cell intravasation

(2014) Seema M. Ehsan et al.   Integrative Biology

Simulation of complex transport of nanoparticles around a tumor using tumor-microenvironment-on-chip

(2014) Bongseop Kwak et al.   JOURNAL OF CONTROLLED RELEASE

Urotensin II Inhibits Doxorubicin-Induced Human Umbilical Vein Endothelial Cell Death by Modulating ATF Expression and via the ERK and Akt Pathway

(2014) Yen-Ling Chen et al.   PLoS One

Tumor-Endothelial Cell Three-dimensional Spheroids: New Aspects to Enhance Radiation and Drug Therapeutics

(2014) Meenakshi Upreti et al.   Translational Oncology

Strategies for advancing cancer nanomedicine

(2013) Vikash P. Chauhan et al.   NATURE MATERIALS

Tumour-on-a-chip provides an optical window into nanoparticle tissue transport

(2013) Alexandre Albanese et al.   Nature Communications

An integrated in vitro model of perfused tumor and cardiac tissue

(2013) Monica Moya et al.   Stem Cell Research & Therapy

Recreating the tumor microenvironment in a bilayer, hyaluronic acid hydrogel construct for the growth of prostate cancer spheroids

(2012) Xian Xu et al.   BIOMATERIALS

On-chip three-dimensional tumor spheroid formation and pump-less perfusion culture using gravity-driven cell aggregation and balanced droplet dispensing

(2012) Taeyoon Kim et al.   Biomicrofluidics

HIF-1 activation induces doxorubicin resistance in MCF7 3-D spheroids via P-glycoprotein expression: a potential model of the chemo-resistance of invasive micropapillary carcinoma of the breast

(2012) Sophie Doublier et al.   BMC CANCER

Opportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacy

(2012) Geeta Mehta et al.   JOURNAL OF CONTROLLED RELEASE

Cancer and Innate Immune System Interactions

(2012) Yanan Liu et al.   JOURNAL OF IMMUNOTHERAPY

Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function

(2012) I. K. Zervantonakis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Moderately Efficient Enzyme: Evolutionary and Physicochemical Trends Shaping Enzyme Parameters

(2011) Arren Bar-Even et al.   BIOCHEMISTRY

High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array

(2010) Yi-Chung Tung et al.   ANALYST

Osteoarthritic chondrocyte-secreted morphogens induce chondrogenic differentiation of human mesenchymal stem cells

(2010) Aereas Aung et al.   ARTHRITIS AND RHEUMATISM

Cell-laden microengineered gelatin methacrylate hydrogels

(2010) Jason W. Nichol et al.   BIOMATERIALS

Photoinitiated polymerization of PEG-diacrylate with lithium phenyl-2,4,6-trimethylbenzoylphosphinate: polymerization rate and cytocompatibility

(2009) Benjamin D. Fairbanks et al.   BIOMATERIALS

Microfluidic system for formation of PC-3 prostate cancer co-culture spheroids

(2009) Amy Y. Hsiao et al.   BIOMATERIALS

A micro cell culture analog (µCCA) with 3-D hydrogel culture of multiple cell lines to assess metabolism-dependent cytotoxicity of anti-cancer drugs

(2009) Jong Hwan Sung et al.   LAB ON A CHIP

A multipurpose microfluidic device designed to mimic microenvironment gradients and develop targeted cancer therapeutics

(2008) Colin L. Walsh et al.   LAB ON A CHIP