Broad spectrum immunomodulation using biomimetic blood cell margination for sepsis therapy

Getting sepsis therapy right

(2015) R. S. Hotchkiss et al.   SCIENCE

An extracorporeal blood-cleansing device for sepsis therapy

(2014) Joo H Kang et al.   NATURE MEDICINE

Inertia-activated cell sorting of immune-specifically labeled cells in a microfluidic device

(2014) Joong Ho Shin et al.   RSC Advances

Synthetic Ligand-Coated Magnetic Nanoparticles for Microfluidic Bacterial Separation from Blood

(2013) Jung-Jae Lee et al.   NANO LETTERS

A microfluidics approach towards high-throughput pathogen removal from blood using margination

(2012) Han Wei Hou et al.   Biomicrofluidics

Sepsis studies need new direction

(2012) Jonathan Cohen et al.   LANCET INFECTIOUS DISEASES

Drotrecogin Alfa (Activated) in Adults with Septic Shock

(2012) V. Marco Ranieri et al.   NEW ENGLAND JOURNAL OF MEDICINE

Resolvin E1 promotes phagocytosis-induced neutrophil apoptosis and accelerates resolution of pulmonary inflammation

(2012) D. El Kebir et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ensemble Models of Neutrophil Trafficking in Severe Sepsis

(2012) Sang O. K. Song et al.   PLoS Computational Biology

Immunomodulatory therapy for sepsis: an update

(2011) Eirini Christaki et al.   Expert Review of Anti-Infective Therapy

Acute removal of common sepsis mediators does not explain the effects of extracorporeal blood purification in experimental sepsis

(2011) Zhi-Yong Peng et al.   KIDNEY INTERNATIONAL

Hypoxia and Inflammation

(2011) Holger K. Eltzschig et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Biomimetic Membrane Device That Modulates the Excessive Inflammatory Response to Sepsis

(2011) Feng Ding et al.   PLoS One

Immunomodulatory cell therapy in sepsis: have we learnt lessons from the past?

(2010) Guillaume Monneret et al.   Expert Review of Anti-Infective Therapy

The response of the host microcirculation to bacterial sepsis: does the pathogen matter?

(2010) Matthieu Legrand et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Deformability based cell margination—A simple microfluidic design for malaria-infected erythrocyte separation

(2010) Han Wei Hou et al.   LAB ON A CHIP

Clinical microfluidics for neutrophil genomics and proteomics

(2010) Kenneth T Kotz et al.   NATURE MEDICINE

Apheresis of Activated Leukocytes with an Immobilized Polymyxin B Filter In Patients with Septic Shock

(2010) Tuneyasu Kumagai et al.   SHOCK

Extracorporeal cell therapy with granulocytes in a pig model of Gram-positive sepsis

(2009) Martin Sauer et al.   CRITICAL CARE MEDICINE

Corticosteroids in the Treatment of Severe Sepsis and Septic Shock in Adults

(2009) Djillali Annane et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Early Use of Polymyxin B Hemoperfusion in Abdominal Septic Shock

(2009) Dinna N. Cruz et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Micromagnetic–microfluidic blood cleansing device

(2009) Chong Wing Yung et al.   LAB ON A CHIP

Determinants of Leukocyte Margination in Rectangular Microchannels

(2009) Abhishek Jain et al.   PLoS One

Effects of hemoadsorption on cytokine removal and short-term survival in septic rats

(2008) Zhi-Yong Peng et al.   CRITICAL CARE MEDICINE

Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production

(2008) Krisztián Németh et al.   NATURE MEDICINE