Journal
ASIAN JOURNAL OF ORGANIC CHEMISTRY
Volume 12, Issue 4, Pages -Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ajoc.202300036
Keywords
2-Ketoaryl azoles; C-H Activation; Catalysis; Cyclization; Heterocycles
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This review summarizes the important breakthrough achieved in the last decade in the synthesis of compounds attached to 2-keto aryl azole moieties, which play a crucial role in medicinal chemistry and drug discovery.
A spectrum of compounds attached to 2-keto aryl azole moieties are found as pivotal building blocks in medicinal chemistry and drug discovery. This is why, the collection of novel methods have been described for the synthesis of these compounds, which are of great significance among organic chemists interested towards the development of new synthetic methods in the fields of natural products, bioactive molecules and materials sciences. This review presents the important breakthrough achieved during last decade towards improvement of approaches for the synthesis of these molecules.
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