Targeting Aedes aegypti Metabolism with Next-Generation Insecticides

An Ethical Overview of the CRISPR-Based Elimination of Anopheles gambiae to Combat Malaria

(2022) India Jane Wise et al.   Journal of Bioethical Inquiry

Bloodmeal regulation in mosquitoes curtails dehydration-induced mortality, altering vectorial capacity

(2022) Christopher J. Holmes et al.   JOURNAL OF INSECT PHYSIOLOGY

Status and Prospects of Botanical Biopesticides in Europe and Mediterranean Countries

(2022) Fatma Acheuk et al.   Biomolecules

Juvenile hormone acts on male accessory gland function via regulating L ‐asparaginase expression and triacylglycerol mobilization in Aedes aegypti

(2022) Xiang‐Yang Lyu et al.   Insect Science

Recommendations for environmental risk assessment of gene drive applications for malaria vector control

(2022) John B. Connolly et al.   MALARIA JOURNAL

Pilot trial using mass field-releases of sterile males produced with the incompatible and sterile insect techniques as part of integrated Aedes aegypti control in Mexico

(2022) Abdiel Martín-Park et al.   PLoS Neglected Tropical Diseases

California Residents’ Perceptions of Gene Drive Systems to Control Mosquito-Borne Disease

(2022) Cynthia E. Schairer et al.   Frontiers in Bioengineering and Biotechnology

The Insulin Receptor: An Important Target for the Development of Novel Medicines and Pesticides

(2022) Xiaohong Zhang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Multiple endocrine factors regulate nutrient mobilization and storage in Aedes aegypti during a gonadotrophic cycle

(2022) Xiaoyi Dou et al.   Insect Science

Potential of Essential Oil-Based Anticholinesterase Insecticides against Anopheles Vectors: A Review

(2022) Thankhoe A. Rants’o et al.   MOLECULES

Chronic depletion of vertebrate lipids in Aedes aegypti cells dysregulates lipid metabolism and inhibits innate immunity without altering dengue infectivity

(2022) Andrew D. Marten et al.   PLoS Neglected Tropical Diseases

Developing the radiation‐based sterile insect technique ( SIT ) for controlling Aedes aegypti : identification of a sterilizing dose

(2022) Chao Chen et al.   PEST MANAGEMENT SCIENCE

Influence of public hesitancy and receptivity on reactive behaviours towards releases of male Wolbachia-Aedes mosquitoes for dengue control

(2022) May O. Lwin et al.   PLoS Neglected Tropical Diseases

Discovery of super–insecticide-resistant dengue mosquitoes in Asia: Threats of concomitant knockdown resistance mutations

(2022) Shinji Kasai et al.   Science Advances

Updating the Insecticide Resistance Status of Aedes aegypti and Aedes albopictus in Asia: A Systematic Review and Meta-Analysis

(2022) Ramdan Zulfa et al.   Tropical Medicine and Infectious Disease

Overexpression of Activated AMPK in the Anopheles stephensi Midgut Impacts Mosquito Metabolism, Reproduction and Plasmodium Resistance

(2021) Chioma Oringanje et al.   Genes

20-Hydroxyecdysone (20E) signaling as a promising target for the chemical control of malaria vectors

(2021) Elodie Ekoka et al.   Parasites & Vectors

Increased size and energy reserves in diapausing eggs of temperate Aedes aegypti populations

(2021) Julián Mensch et al.   JOURNAL OF INSECT PHYSIOLOGY

Trehalase inhibition by validamycin A may be a promising target to design new fungicides and insecticides

(2021) María‐Dolores García et al.   PEST MANAGEMENT SCIENCE

Following de novo triglyceride dynamics in ovaries of Aedes aegypti during the previtellogenic stage

(2021) Lilian Valadares Tose et al.   Scientific Reports

Public sentiments towards the use of Wolbachia-Aedes technology in Singapore

(2021) Christina Liew et al.   BMC PUBLIC HEALTH

Blood glucose promotes dengue virus infection in the mosquito Aedes aegypti

(2021) Shih-Che Weng et al.   Parasites & Vectors

Suppression of female fertility in Aedes aegypti with a CRISPR-targeted male-sterile mutation

(2021) Jieyan Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Suppressing mosquito populations with precision guided sterile males

(2021) Ming Li et al.   Nature Communications

Determinants of stakeholders’ attitudes and intentions toward supporting the use of Wolbachia-infected Aedes mosquitoes for dengue control

(2021) Ahmad Firdhaus Arham et al.   BMC PUBLIC HEALTH

Diatomaceous Earth for Arthropod Pest Control: Back to the Future

(2021) Valeria Zeni et al.   MOLECULES

Nutritional status significantly affects toxicological endpoints in the CDC bottle bioassay

(2021) Edmund J Norris et al.   PEST MANAGEMENT SCIENCE

A Household-Based Survey to Understand Factors Influencing Awareness, Attitudes and Knowledge towards Wolbachia-Aedes Technology

(2021) Li Ting Soh et al.   International Journal of Environmental Research and Public Health

ٍSome biologically active microorganisms have the potential to suppress mosquito larvae (Culex pipiens, Diptera: Culicidae)

(2021) Mohamed I. Hegazy et al.   SAUDI JOURNAL OF BIOLOGICAL SCIENCES

Implications of Sublethal Insecticide Exposure and the Development of Resistance on Mosquito Physiology, Behavior, and Pathogen Transmission

(2021) Felipe Andreazza et al.   Insects

Effects of gamma radiation on the reproductive viability of Aedes aegypti and its descendants (Diptera: Culicidae)

(2021) Edvane Borges Silva et al.   ACTA TROPICA

Validamycin A Delays Development and Prevents Flight in Aedes aegypti (Diptera: Culicidae)

(2020) Andrew D Marten et al.   JOURNAL OF MEDICAL ENTOMOLOGY

Public health concerns over gene-drive mosquitoes: will future use of gene-drive snails for schistosomiasis control gain increased level of community acceptance?

(2020) Damilare O. Famakinde   Pathogens and Global Health

Toward the Definition of Efficacy and Safety Criteria for Advancing Gene Drive-Modified Mosquitoes to Field Testing

(2020) Stephanie L. James et al.   VECTOR-BORNE AND ZOONOTIC DISEASES

Transcriptome analysis of Aedes aegypti Aag2 cells in response to dengue virus-2 infection

(2020) Man-jin Li et al.   Parasites & Vectors

Effect of Larval Food Availability on Adult Aedes Aegypti (Diptera: Culicidae) Fitness and Susceptibility to Zika Infection

(2020) Carlucio Rocha-Santos et al.   JOURNAL OF MEDICAL ENTOMOLOGY

Mosquito‐infecting virus Espirito Santo virus inhibits replication and spread of dengue virus

(2020) Avian V. White et al.   JOURNAL OF MEDICAL VIROLOGY

Transmission competence of a new mesonivirus, Yichang virus, in mosquitoes and its interference with representative flaviviruses

(2020) Guoguo Ye et al.   PLoS Neglected Tropical Diseases

Small-Molecule Agonists of Ae. aegypti Neuropeptide Y Receptor Block Mosquito Biting

(2019) Laura B. Duvall et al.   CELL

Resistance to pyrethroid and organophosphate insecticides, and the geographical distribution and polymorphisms of target-site mutations in voltage-gated sodium channel and acetylcholinesterase 1 genes in Anopheles sinensis populations in Shanghai, China

(2019) Yuan Fang et al.   Parasites & Vectors

Toward a blood-free diet for Anopheles darlingi (Diptera: Culicidae)

(2019) Glaucilene da Silva Costa et al.   JOURNAL OF MEDICAL ENTOMOLOGY

The consequences of Brugia malayi infection on the flight and energy resources of Aedes aegypti mosquitoes

(2019) Alastair G. T. Somerville et al.   Scientific Reports

Pyrethroid resistance in the dengue vector Aedes aegypti in Southeast Asia: present situation and prospects for management

(2018) Zheng Hua Amelia-Yap et al.   Parasites & Vectors

Dual Insect specific virus infection limits Arbovirus replication in Aedes mosquito cells

(2018) Michaela J. Schultz et al.   VIROLOGY

The Effect of SkitoSnack, an Artificial Blood Meal Replacement, on Aedes aegypti Life History Traits and Gut Microbiota

(2018) Kristina K. Gonzales et al.   Scientific Reports

Vector biology meets disease control: using basic research to fight vector-borne diseases

(2018) W. Robert Shaw et al.   Nature Microbiology

Fresh-blood-free diet for rearing malaria mosquito vectors

(2018) Joana Marques et al.   Scientific Reports

Integrated Aedes management for the control of Aedes-borne diseases

(2018) David Roiz et al.   PLoS Neglected Tropical Diseases

Suppressing the activity of trehalase with validamycin disrupts the trehalose and chitin biosynthesis pathways in the rice brown planthopper, Nilaparvata lugens

(2017) Bin Tang et al.   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Germline Cas9 expression yields highly efficient genome engineering in a major worldwide disease vector,Aedes aegypti

(2017) Ming Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Perturbed cholesterol and vesicular trafficking associated with dengue blocking in Wolbachia-infected Aedes aegypti cells

(2017) Vincent Geoghegan et al.   Nature Communications

Malpighian Tubules as Novel Targets for Mosquito Control

(2017) Peter Piermarini et al.   International Journal of Environmental Research and Public Health

Contemporary status of insecticide resistance in the major Aedes vectors of arboviruses infecting humans

(2017) Catherine L. Moyes et al.   PLoS Neglected Tropical Diseases

Study on the Effect of Wing Bud Chitin Metabolism and Its Developmental Network Genes in the Brown Planthopper, Nilaparvata lugens, by Knockdown of TRE Gene

(2017) Lu Zhang et al.   Frontiers in Physiology

Differential outcomes of Zika virus infection in Aedes aegypti orally challenged with infectious blood meals and infectious protein meals

(2017) Yan-Jang S. Huang et al.   PLoS One

Wolbachia Modulates Lipid Metabolism in Aedes albopictus Mosquito Cells

(2016) Jennifer C. Molloy et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Interferon-Induced Spermidine-Spermine Acetyltransferase and Polyamine Depletion Restrict Zika and Chikungunya Viruses

(2016) Bryan C. Mounce et al.   Cell Host & Microbe

Zika Virus in the Americas — Yet Another Arbovirus Threat

(2016) Anthony S. Fauci et al.   NEW ENGLAND JOURNAL OF MEDICINE

An insecticide resistance-breaking mosquitocide targeting inward rectifier potassium channels in vectors of Zika virus and malaria

(2016) Daniel R. Swale et al.   Scientific Reports

Artificial Diets for Mosquitoes

(2016) Kristina Gonzales et al.   International Journal of Environmental Research and Public Health

Costs of Three Wolbachia Infections on the Survival of Aedes aegypti Larvae under Starvation Conditions

(2016) Perran A. Ross et al.   PLoS Neglected Tropical Diseases

Disrupting Mosquito Reproduction and Parasite Development for Malaria Control

(2016) Lauren M. Childs et al.   PLoS Pathogens

Sodium Channel Mutations and Pyrethroid Resistance in Aedes aegypti

(2016) Yuzhe Du et al.   Insects

Insecticide Resistance in Mosquitoes: Impact, Mechanisms, and Research Directions

(2015) Nannan Liu   Annual Review of Entomology

Thiosemicarbazones as Aedes aegypti larvicidal

(2015) João Bosco P. da Silva et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Sugar-sensitive neurone responses and sugar feeding preferences influence lifespan and biting behaviours of the Afrotropical malaria mosquito, Anopheles gambiae

(2015) Sébastien Kessler et al.   JOURNAL OF COMPARATIVE PHYSIOLOGY A-NEUROETHOLOGY SENSORY NEURAL AND BEHAVIORAL PHYSIOLOGY

The use of a chemically defined artificial diet as a tool to study Aedes aegypti physiology

(2015) Octávio A.C. Talyuli et al.   JOURNAL OF INSECT PHYSIOLOGY

Sterol Carrier Protein 2, a Critical Host Factor for Dengue Virus Infection, Alters the Cholesterol Distribution in Mosquito Aag2 Cells

(2015) Qiang Fu et al.   JOURNAL OF MEDICAL ENTOMOLOGY

Late-instar Behavior ofAedes aegypti(Diptera: Culicidae) Larvae in Different Thermal and Nutritive Environments

(2015) Michael H. Reiskind et al.   JOURNAL OF MEDICAL ENTOMOLOGY

Small mosquitoes, large implications: crowding and starvation affects gene expression and nutrient accumulation in Aedes aegypti

(2015) David P Price et al.   Parasites & Vectors

Potential for Co-Infection of a Mosquito-Specific Flavivirus, Nhumirim Virus, to Block West Nile Virus Transmission in Mosquitoes

(2015) Silvina Goenaga et al.   Viruses-Basel

Genome Engineering with CRISPR-Cas9 in the Mosquito Aedes aegypti

(2015) Kathryn E. Kistler et al.   Cell Reports

Temporal Coordination of Carbohydrate Metabolism during Mosquito Reproduction

(2015) Yuan Hou et al.   PLoS Genetics

Insect trehalase: Physiological significance and potential applications

(2014) E. Shukla et al.   GLYCOBIOLOGY

Trehalase Activity in Fungus-Growing Termite, Odontotermes feae (Isoptera: Termitideae) and Inhibitory Effect of Validamycin

(2014) Nujira Tatun et al.   JOURNAL OF ECONOMIC ENTOMOLOGY

The major bioactive components of seaweeds and their mosquitocidal potential

(2014) Ke-Xin Yu et al.   PARASITOLOGY RESEARCH

The Modulation of the Symbiont/Host Interaction between Wolbachia pipientis and Aedes fluviatilis Embryos by Glycogen Metabolism

(2014) Mariana da Rocha Fernandes et al.   PLoS One

The global distribution and burden of dengue

(2013) Samir Bhatt et al.   NATURE

TALEN-Based Gene Disruption in the Dengue Vector Aedes aegypti

(2013) Azadeh Aryan et al.   PLoS One

Impact of trehalose transporter knockdown on Anopheles gambiae stress adaptation and susceptibility to Plasmodium falciparum infection

(2013) K. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ERK signaling couples nutrient status to antiviral defense in the insect gut

(2013) J. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Native Wolbachia Symbionts Limit Transmission of Dengue Virus in Aedes albopictus

(2013) Laurence Mousson et al.   PLoS Neglected Tropical Diseases

A Wolbachia wMel Transinfection in Aedes albopictus Is Not Detrimental to Host Fitness and Inhibits Chikungunya Virus

(2013) Marcus S. C. Blagrove et al.   PLoS Neglected Tropical Diseases

Trehalose as an indicator of desiccation stress in Drosophila melanogaster larvae: A potential marker of anhydrobiosis

(2012) Leena J. Thorat et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A new dibenzoylhydrazine with insecticidal activity againstAnophelesmosquito larvae

(2012) Evangelia Morou et al.   PEST MANAGEMENT SCIENCE

Deficiencies in acetyl-CoA carboxylase and fatty acid synthase 1 differentially affect eggshell formation and blood meal digestion in Aedes aegypti

(2011) Amy Alabaster et al.   INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY

The wMel Wolbachia strain blocks dengue and invades caged Aedes aegypti populations

(2011) T. Walker et al.   NATURE

Successful establishment of Wolbachia in Aedes populations to suppress dengue transmission

(2011) A. A. Hoffmann et al.   NATURE

Comparison of Life History Characteristics of the Genetically Modified OX513A Line and a Wild Type Strain of Aedes aegypti

(2011) Irka Bargielowski et al.   PLoS One

Germ band retraction as a landmark in glucose metabolism during Aedes aegypti embryogenesis

(2010) Wagner Vital et al.   BMC DEVELOPMENTAL BIOLOGY

The impact of larval and adult dietary restriction on lifespan, reproduction and growth in the mosquito Aedes aegypti

(2010) Teresa K. Joy et al.   EXPERIMENTAL GERONTOLOGY

Feeding-based RNA interference of atrehalose phosphate synthasegene in the brown planthopper,Nilaparvata lugens

(2010) J. Chen et al.   INSECT MOLECULAR BIOLOGY

Long-term effects of the trehalase inhibitor trehazolin on trehalase activity in locust flight muscle

(2010) G. Wegener et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Different Functions of the Insect Soluble and Membrane-Bound Trehalase Genes in Chitin Biosynthesis Revealed by RNA Interference

(2010) Jie Chen et al.   PLoS One

The Native Wolbachia Endosymbionts of Drosophila melanogaster and Culex quinquefasciatus Increase Host Resistance to West Nile Virus Infection

(2010) Robert L. Glaser et al.   PLoS One

Female-specific flightless phenotype for mosquito control

(2010) G. Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Endosymbiotic Bacterium Wolbachia Induces Resistance to Dengue Virus in Aedes aegypti

(2010) Guowu Bian et al.   PLoS Pathogens

Insect Fat Body: Energy, Metabolism, and Regulation

(2009) Estela L. Arrese et al.   Annual Review of Entomology

A Wolbachia Symbiont in Aedes aegypti Limits Infection with Dengue, Chikungunya, and Plasmodium

(2009) Luciano A. Moreira et al.   CELL

Fate and effects of the trehalase inhibitor trehazolin in the migratory locust (Locusta migratoria)

(2009) Martina Liebl et al.   JOURNAL OF INSECT PHYSIOLOGY

Stable Introduction of a Life-Shortening Wolbachia Infection into the Mosquito Aedes aegypti

(2009) C. J. McMeniman et al.   SCIENCE

Nutritional Stress Affects Mosquito Survival and Vector Competence for West Nile Virus

(2008) Rajeev Vaidyanathan et al.   VECTOR-BORNE AND ZOONOTIC DISEASES