Article
Medical Laboratory Technology
Ichiro Wakabayashi
Summary: This study found an association between polycythemia and cardiometabolic risk factors, including visceral obesity, hypertension, dyslipidemia, diabetes, and metabolic syndrome, in the general population. This association was independent of smoking.
CLINICA CHIMICA ACTA
(2022)
Article
Multidisciplinary Sciences
Yun Soo Hong, Kyung Uk Jung, Sanjay Rampal, Di Zhao, Eliseo Guallar, Seungho Ryu, Yoosoo Chang, Hyung Ook Kim, Hungdai Kim, Ho-Kyung Chun, Chong Il Sohn, Hocheol Shin, Juhee Cho
Summary: Hemorrhoidal disease is highly prevalent and has a significant impact on quality of life. The prevalence of hemorrhoidal disease is higher in parous women and lower in nulliparous women. Age, sex, smoking, overweight, and hypertension are independent risk factors for hemorrhoidal disease. Body mass index and waist circumference are positively associated with hemorrhoidal disease in parous women.
SCIENTIFIC REPORTS
(2022)
Article
Geriatrics & Gerontology
Matti Hyvarinen, Juha Karvanen, Hanna-Kaarina Juppi, Jari E. Karppinen, Tuija H. Tammelin, Vuokko Kovanen, Pauliina Aukee, Sarianna Sipila, Timo Rantalainen, Eija K. Laakkonen
Summary: The objective of this study was to examine the associations between menopausal symptoms and cardiometabolic risk factors. The authors conducted a cross-sectional and longitudinal study on a representative population sample of women aged 47-55 years. The results showed modest positive associations between menopausal symptoms and cholesterol and fat mass measures, but these associations disappeared after adjusting for confounders. Menopausal symptoms did not predict changes in risk factors during the follow-up period.
Article
Public, Environmental & Occupational Health
Dong Wang, Hongxia Gao, Xin Xu, Dan Han, Kuan Yi, Guilin Hou
Summary: This study aimed to understand the effect of physical health on the subjective wellbeing (SWB) of middle-aged and elderly women (MAEW) in China. The results indicated that most of the respondents reported satisfactory SWB. Factors such as self-rated health, 2-week morbidity, BMI, and physical exercise significantly influenced the SWB of MAEW. While smoking and drinking status were not related to SWB. Demographic indicators such as registered residence, income, and social status also had a significant impact on the SWB of MAEW.
Article
Cardiac & Cardiovascular Systems
Juhua Luo, Allison Hodge, Michael Hendryx, Julie E. Byles
Summary: This study found that in middle-aged women, initial BMI, rapid weight increase, early age of obesity onset, and greater obese-years are positively associated with the risk of developing type 2 diabetes mellitus. Therefore, slowing down weight increases, delaying the onset of obesity, or reducing cumulative exposure to obesity may substantially lower the risk of developing type 2 diabetes.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2021)
Article
Medicine, General & Internal
Jungeun Park, Mi Kyoung Son, Hyun-Young Park
Summary: This study aimed to investigate lipid changes in Korean middle-aged women during the perimenopausal period. The results showed that lipid levels significantly increased from 3 to 5 years before menopause to 1 year after menopause in all women, regardless of their premenopausal body mass index. However, lipid changes slowed down after 1 year postmenopause, indicating the importance of early intervention strategies for cardiovascular disease prevention in women.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2023)
Article
Public, Environmental & Occupational Health
Elzbieta Ciesla, Ewa Stochmal, Stanislaw Gluszek, Edyta Suliga
Summary: This study found that there may be an association between breastfeeding duration and the risk of excessive weight and abdominal obesity in middle-aged women who have gone through menopause, while no significant relationship was found for women who have not yet gone through menopause.
Article
Endocrinology & Metabolism
Ling Bai, Xi Yang, Ziyi Sun, Zuojie Luo, Li Li, Xinghuan Liang, Jia Zhou, Liheng Meng, Yang Peng, Yingfen Qin
Summary: This study aimed to explore the association between reproductive variables and metabolic syndrome (MetS) among Chinese women aged 40 and older in Guangxi. The results showed that multiparity and menopausal status were associated with the development of MetS. Further investigation is needed to verify these findings.
JOURNAL OF DIABETES
(2023)
Article
Endocrinology & Metabolism
Laura Cleven, Anna Dziuba, Janina Krell-Roesch, Steffen C. E. Schmidt, Klaus Boes, Darko Jekauc, Alexander Woll
Summary: The study found that there is a significant association between physical activity and the onset of risk factors related to metabolic syndrome in middle-aged adults. Engaging in physical activity, including outdoor sports, can reduce the risk of developing elevated waist circumference, elevated triglycerides, reduced high-density lipoprotein cholesterol, elevated blood pressure, and elevated blood glucose.
DIABETOLOGY & METABOLIC SYNDROME
(2023)
Article
Public, Environmental & Occupational Health
Ziyue Sheng, Shang Lou, Jin Cao, Weidi Sun, Yaojia Shen, Yunhan Xu, Ziyang Ren, Wen Liu, Qian Yi, Peige Song
Summary: This study investigates the associations of obesity phenotypes with hypertension stages, phenotypes, and transitions among middle-aged and older Chinese. The results show that different obesity phenotypes are associated with different stages and phenotypes of hypertension, and there is an interaction effect of sex between obesity phenotypes and hypertension stages.
EPIDEMIOLOGY AND HEALTH
(2023)
Article
Oncology
Ana M. Rodriguez, Efstathia Polychronopoulou, Enshuo Hsu, Rahul Shah, Kelly Lamiman, Yong-Fang Kuo
Summary: The study investigated the relationship between Hispanic women and endometrial hyperplasia symptoms, hyperplasia with atypia, and cancer, finding that non-Hispanic Blacks and Hispanics are more prone to endometrial hyperplasia symptoms; patients with obesity and diabetes are at a higher risk of developing endometrial cancer.
GYNECOLOGIC ONCOLOGY
(2021)
Article
Nutrition & Dietetics
Hongguang Yang, Minjie Zhang, Jiaqi Nie, Minzhe Zhang, Gaolei Lu, Rui Chen, Qiqiang He
Summary: This study investigated the associations of six obesity-related indices with prediabetes regression. The results showed that low initial obesity-related indices and reduction in triglyceride glucose levels were significantly related to prediabetes regression to normoglycemia.
FRONTIERS IN NUTRITION
(2023)
Article
Multidisciplinary Sciences
Gomathi Munusamy, Ramesh Shanmugam
Summary: The study aims to evaluate the effect of a 12-week structured interventional strategy program, containing integrated education and supervised physical activity interventions, on middle-aged adolescents.
Article
Nutrition & Dietetics
Siew-Keah Lee, Ang-Lim Chua, Clement Heng Yew Fong, Brian Cong Hao Ban, Wen Ling Ng, Jing Feng Kong, Yik-Ling Chew, Kai Bin Liew
Summary: This study aims to determine the self-assessment of INTERHEART risk classification among the middle-aged community in Malaysia. The results showed that approximately 45% of middle-aged respondents in Malaysia are at moderate-to-high risk of cardiovascular events, with men being more likely to develop CVD compared to women. Poultry/meat intake, physical inactivity, and second-hand smoke exposure are the most prevalent risk factors among the respondents.
Article
Multidisciplinary Sciences
Saifur Rahman Chowdhury, Md. Nazrul Islam, Tasbeen Akhtar Sheekha, Shirmin Bintay Kader, Ahmed Hossain
Summary: In this study, the prevalence and determinants of risk factors for non-noncommunicable diseases, such as smoking, overweight/obesity, and hypertension, among reproductive-age women in Bangladesh were investigated. Factors such as age, education, wealth index, and geographic location were found to be associated with these risk factors. The findings emphasize the importance of targeted public health interventions to promote physical activity and reduce tobacco use, particularly in the coastal region.
Article
Cardiac & Cardiovascular Systems
Eunhee Chung, Kaylan M. Haizlip, Leslie A. Leinwand
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
(2018)
Article
Physiology
Michael A. Garza, Emily A. Wason, Justin R. Cruger, Eunhee Chung, John Q. Zhang
JOURNAL OF PHYSIOLOGICAL SCIENCES
(2019)
Article
Biochemistry & Molecular Biology
Eunhee Chung, Salvatore N. Campise, Hayli E. Joiner, Michael D. Tomison, Gurvinder Kaur, Jannette M. Dufour, Lillian Cole, Latha Ramalingam, Naima Moustaid-Moussa, Chwan-Li Shen
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2019)
Article
Nutrition & Dietetics
Eunhee Chung, Katherine A. Grue, Gurvinder Kaur, Brian Mallory, Christian R. Serrano, Sarah L. Ullevig, Kameswara Rao Kottapalli, Soo Chan Lee, Jannette M. Dufour, Chwan-Li Shen, Masataka Umeda
NUTRITION RESEARCH
(2019)
Article
Biochemistry & Molecular Biology
Moamen M. Elmassry, Eunhee Chung, Jay J. Cao, Abdul N. Hamood, Chwan-Li Shen
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
(2020)
Article
Environmental Sciences
Masataka Umeda, Sarah L. Ullevig, Eunhee Chung, Youngdeok Kim, Tanya J. Escobedo, Christopher J. Zeitz
Summary: Research shows a high prevalence of food insecurity among college students, which may lead to depression and increased risk of pain. The study found a positive association between food insecurity, depression, and pain interference, with depression playing a significant mediating role in the relationship between food insecurity and pain interference.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Nutrition & Dietetics
Eunhee Chung, Moamen M. Elmassry, Jay J. Cao, Gurvinder Kaur, Jannette M. Dufour, Abdul N. Hamood, Chwan-Li Shen
Summary: The study showed that supplementation with geranylgeraniol (GGOH) can improve glucose homeostasis and bone microstructure in obese mice by suppressing inflammation and modifying gut microbiota composition. This includes improving glucose tolerance and insulin sensitivity, reducing production of pro-inflammatory adipokines, and enhancing bone formation markers while reducing bone resorption markers. Furthermore, GGOH supplementation was associated with changes in the gut microbiome composition, suggesting a potential mechanism for its physiological benefits.
NUTRITION RESEARCH
(2021)
Article
Multidisciplinary Sciences
Eunhee Chung, Kassandra Gonzalez, Sarah L. Ullevig, John Zhang, Masataka Umeda
Summary: The study found that obesity, rather than diet alone, negatively affected cardiac adaptation during pregnancy and postpartum.
SCIENTIFIC REPORTS
(2021)
Article
Biochemistry & Molecular Biology
Eunhee Chung, Samuel D. Offei, U-Ter Aondo Jia, Juan Estevez, Yessenia Perez, Hadi D. Arman, Francis K. Yoshimoto
Summary: Researchers have discovered that mice lacking the gene for P450 8B1 show resistance to weight gain and improved glucose tolerance when fed a high-fat diet. This finding suggests that inhibiting P450 8B1 could be a potential treatment for obesity-associated metabolic disorders.
Article
Biochemistry & Molecular Biology
Andrea Chinas Merlin, Kassandra Gonzalez, Sarah Mockler, Yessenia Perez, U-Ter Aondo Jia, Adam J. Chicco, Sarah L. Ullevig, Eunhee Chung
Summary: Switching to a standard chow diet after weaning can alleviate the detrimental effects of maternal and postnatal high-fat/high-sucrose diet on metabolic disorders and cardiac mitochondrial dysfunction in adult male mouse offspring.
Article
Biochemistry & Molecular Biology
Chwan-Li Shen, Moamen M. Elmassry, Katherine Grue, Hayli E. Joiner, A. Unique Jacobo, Abdul Hamood, Eunhee Chung
Summary: Natural bioactive compounds, such as geranylgeraniol and green tea polyphenols, were found to alleviate muscle atrophy and modify gut microbiome composition in mice fed a high-fat diet. The combination of geranylgeraniol and green tea polyphenols resulted in decreased body and fat mass, increased skeletal muscle mass, and changes in gut microbiota composition.
Article
Biochemistry & Molecular Biology
Chwan-Li Shen, Jannette M. Dufour, Jonathan M. Miranda, Gurvinder Kaur, Eunhee Chung, Latha Ramalingam, Naima Moustaid-Moussa, Jay J. Cao
Summary: This study examined the combined effects of green tea polyphenols and geranylgeraniol on glucose homeostasis and bone remodeling in obese mice. Results showed that green tea polyphenols supplementation improved glucose tolerance in obese mice. However, the combined supplementation of geranylgeraniol and green tea polyphenols compromised the effects on glucose homeostasis and bone remodeling in obese mice.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Integrative & Complementary Medicine
T. Brock Symons, Jinho Park, Joo Hyun Kim, Eun Hye Kwon, Jesse Delacruz, Junghoon Lee, Yoonjung Park, Eunhee Chung, Sukho Lee
Summary: This study compared the effects of acupuncture, electro-acupuncture, and electrical stimulation on cast-induced skeletal muscle atrophy. The results showed that all three treatments were effective in attenuating skeletal muscle atrophy caused by cast-immobilization.
INTEGRATIVE MEDICINE RESEARCH
(2023)
Article
Education & Educational Research
Masataka Umeda, Youngdeok Kim, Se-Woong Park, Eunhee Chung, Sarah L. Ullevig
Summary: This study aimed to investigate the prevalence of food insecurity (FI) among college students during the COVID-19 pandemic in April 2021 using a cross-sectional design. The study also examined the moderating role of first-generation student status in the relationship between FI and grade point average (GPA). A total of 360 students, mostly from upper-level kinesiology courses, participated in the study. General linear models were used to predict GPA based on food security status, psychological health, and bodily pain, with subgroup analysis conducted based on first-generation student status. The results showed that approximately 19% of the students were classified as having FI. Those with FI had lower GPA and poorer health compared to those without FI. The link between FI and GPA was moderated by first-generation student status, with a more pronounced negative impact of FI on GPA observed among non-first-generation students.
JOURNAL OF AMERICAN COLLEGE HEALTH
(2023)
Article
Nutrition & Dietetics
Eunhee Chung, Moamen M. Elmassry, Pratibha Kottapalli, Kameswara Rao Kottapalli, Gurvinder Kaur, Jannette M. Dufour, Kandis Wright, Latha Ramalingam, Naima Moustaid-Moussa, Rui Wang, Abdul N. Hamood, Chwan-Li Shen
NUTRITION RESEARCH
(2020)