A Prospective, Randomized, Masked, Placebo-Controlled Multisite Clinical Study of Grapiprant, an EP4 Prostaglandin Receptor Antagonist (PRA), in Dogs with Osteoarthritis

Pharmacokinetic comparison of oral tablet and suspension formulations of grapiprant, a novel therapeutic for the pain and inflammation of osteoarthritis in dogs

(2016) L. C. Rausch-Derra et al.   JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS

Evaluation of the safety of long-term, daily oral administration of grapiprant, a novel drug for treatment of osteoarthritic pain and inflammation, in healthy dogs

(2015) Lesley C. Rausch-Derra et al.   AMERICAN JOURNAL OF VETERINARY RESEARCH

Power of treatment success definitions when the Canine Brief Pain Inventory is used to evaluate carprofen treatment for the control of pain and inflammation in dogs with osteoarthritis

(2013) Dorothy Cimino Brown et al.   AMERICAN JOURNAL OF VETERINARY RESEARCH

Systematic Review of Nonsteroidal Anti-Inflammatory Drug-Induced Adverse Effects in Dogs

(2013) B.P. Monteiro-Steagall et al.   JOURNAL OF VETERINARY INTERNAL MEDICINE

Caregiver placebo effect for dogs with lameness from osteoarthritis

(2012) Michael G. Conzemius et al.   JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION

Clinical pharmacology of nonsteroidal anti-inflammatory drugs in dogs

(2011) Butch KuKanich et al.   VETERINARY ANAESTHESIA AND ANALGESIA

Review of the safety and efficacy of long-term NSAID use in the treatment of canine osteoarthritis

(2010) J. F. Innes et al.   VETERINARY RECORD

Ability of the Canine Brief Pain Inventory to detect response to treatment in dogs with osteoarthritis

(2008) Dorothy Cimino Brown et al.   JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION

Effects of the selective EP4antagonist, CJ-023,423 on chronic inflammation and bone destruction in rat adjuvant-induced arthritis

(2008) Takako Okumura et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

An Update on Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) in Small Animals

(2008) Mark G. Papich   VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE