Article
Neurosciences
Shan Xu, Xingyu Liu, Jorge Almeida, Dietmar Heinke
Summary: Recent studies have shown that both the ventral and dorsal visual streams respond to action relations between objects, with contributions from each stream differentiating their neural activities. The involvement of either stream in the automatic extraction of action relations is not solely dependent on familiarity of the objects, suggesting a division of labor between the two visual streams.
Article
Neurosciences
Giuseppe Marrazzo, Maarten J. Vaessen, Beatrice de Gelder
Summary: The study investigates the impact of critical category attributes like emotional expression on brain activity, showing that the type of task is the main determinant of brain activity, with higher activity in the VLPFC during explicit tasks. Results suggest the importance of task and category attributes in understanding the functional organization of the high-level visual cortex.
Article
Computer Science, Artificial Intelligence
Meng Xing, Zhiyong Feng, Yong Su, Weilong Peng, Jianhai Zhang
Summary: The proposed VD-ZSAR method extracts nonredundant visual features based on the Ventral & Dorsal Stream Theory, and learns the correlation between actions through a visual-semantic joint embedding space. Experimental results demonstrate the favorable performance of the approach across multiple datasets.
PATTERN RECOGNITION
(2021)
Review
Behavioral Sciences
Mingtong Liu, Chang Hong Liu, Shuang Zheng, Ke Zhao, Xiaolan Fu
Summary: This study used an ALE method to meta-analyze 96 neuroimaging studies and found that the left fusiform face area plays a crucial role in facial expression processing. A revised model was constructed with prominent roles assigned to the amygdala, FFA, occipital gyrus, and inferior frontal gyrus in a co-activating neural network.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2021)
Article
Neurosciences
Ibrahim Kiremitci, Ozgur Yilmaz, Emin Celik, Mo Shahdloo, Alexander G. Huth, Tolga Cukur
Summary: Attention plays a crucial role in selectively listening to desired speakers in noisy environments, causing broad modulations in speech representations at multiple levels and growing stronger towards later stages of processing. Unattended speech is still represented up to the semantic level in parabelt auditory cortex.
Review
Neurosciences
Sujeevini Sujanthan, Amir Shmuel, Janine Dale Mendola
Summary: This article reviews the application of resting-state functional magnetic resonance imaging (RS-fMRI) in the field of optic neuropathies. The studies show that there are changes in brain activity and functional connectivity in patients with optic neuropathies, and these changes vary across different types of diseases. Additionally, RS-fMRI studies of optic neuropathies demonstrate recovery of brain activity in certain areas.
FRONTIERS IN HUMAN NEUROSCIENCE
(2022)
Article
Neurosciences
Gundula Seidel, Michel Rijntjes, Daniel Guellmar, Cornelius Weiller, Farsin Hamzei
Summary: The left hemisphere tool-use network consists of distinct streams with different computational abilities, and the ventral pathway is associated with conceptual understanding. An fMRI study was conducted to investigate the interaction between these streams when confronted with novel tools. The study found that during concept acquisition of unknown tools, there was an EC between dorsal and ventral streams, while when previously unknown tools were presented again, EC was prominent only between dorsal stream areas. The findings suggest that the ventral stream is involved in understanding the concept of a novel tool, while the dorsal stream areas are sufficient once the concept is acquired.
Article
Neurosciences
Edmund T. Rolls, Gustavo Deco, Chu-Chung Huang, Jianfeng Feng
Summary: This study investigates the effective connectivity in the human hippocampal memory system, revealing the directionality and strength of the connections between different brain regions. By connecting different information streams with the hippocampus, the hippocampal function is optimized.
Article
Psychology, Multidisciplinary
Sophia Vinci-Booher, Karin H. James
Summary: Handwriting is a complex visual-motor skill supported by a widespread neural system including ventral-temporal, parietal, and frontal motor regions in adults. The neural system supporting handwriting is largely established by 8 years of age, with different parietal and frontal motor involvement in children compared to adults. The individual differences in parietal and frontal motor activation during handwriting are related to emerging literacy skills, suggesting that the neural system changes over the course of development.
FRONTIERS IN PSYCHOLOGY
(2021)
Article
Neurosciences
Settimio Ziccarelli, Antonino Errante, Leonardo Fogassi
Summary: Action observation recruits visual areas and activates the extended action observation network (eAON). This study investigated the activation of eAON during observation of point-light displays (PLDs) and fully visible hand grasping actions. Results showed that both conditions elicited similar motor resonance mechanisms in eAON. The study suggests that kinematic features conveyed by PLDs stimuli can be disentangled within eAON, providing insights into action recognition, imitation, and motor learning.
HUMAN BRAIN MAPPING
(2022)
Article
Psychology, Multidisciplinary
Julio Plata-Bello, Nicole Privato, Cristian Modrono, Yaiza Perez-Martin, Africa Borges, Jose Luis Gonzalez-Mora, Tim Hodgson
Summary: The aim of this study was to analyze the brain activity patterns during the observation of painful expressions and establish the relationship between this activity and the scores obtained on the Interpersonal Reactivity Index (IRI). Observing painful expressions led to increased activity in specific regions of the frontal, temporal, and parietal lobes. The regression analysis demonstrated a positive correlation between brain activity during the observation of pain and empathic concern scores on the IRI.
BEHAVIORAL SCIENCES
(2023)
Article
Neurosciences
Margaret Prenger, Madeline Gilchrist, Kathryne Van Hedger, Ken N. Seergobin, Adrian M. Owen, Penny A. Macdonald
Summary: Humor comprehension and appreciation are cognitive processes involving different brain regions. The dorsal striatum is important for humor comprehension, while the ventral striatum plays a critical role in humor appreciation.
JOURNAL OF NEUROSCIENCE
(2023)
Article
Neurosciences
Sadjad Sadeghi, Stephanie N. L. Schmidt, Daniela Mier, Joachim Hass
Summary: This study used dynamic causal modeling (DCM) to determine the effective connectivity of the human mirror neuron system (MNS) during different social cognition tasks. The results showed that there were effective connections from the superior temporal sulcus (STS) to the inferior parietal lobule (IPL) and Brodmann area 44 (BA44) in all social cognition processes. Additional mutual connections were found in the imitation task.
SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE
(2022)
Article
Psychology, Developmental
Vladislav Ayzenberg, Michael C. Granovetter, Sophia Robert, Christina Patterson, Marlene Behrmann
Summary: Hemispherectomy is a surgical procedure used to treat drug-resistant epilepsy. This study found that pediatric patients who undergo hemispherectomy show a high level of perceptual function despite losing certain visual pathways. The study also discovered that the ventral visual pathway has a greater ability to reorganize compared to the dorsal pathway.
DEVELOPMENTAL COGNITIVE NEUROSCIENCE
(2023)
Article
Behavioral Sciences
Xiaojue Zhou, Daniel A. Stehr, John Pyles, Emily D. Grossman
Summary: Observing the actions of others activates a core action observation network in the brain, which includes inferior frontal cortex, posterior superior temporal sulcus, and inferior parietal lobule. Each region within this network has different functional properties, such as representing the perceptual properties of action, predicting action outcomes, and inferring the goals of the actor. Recent evidence suggests that attention to the kinematics of the actor shapes neural representations in the posterior superior temporal sulcus. This study explores how attention alters network connectivity within the action observation network. The findings show that connectivity between the posterior superior temporal sulcus and the inferior frontal cortex, as well as bilateral extended superior temporal sulcus, is strengthened during action observation when attention is focused on the action itself rather than the goal. The results also suggest that the attention-modulated regions mainly consist of the fronto-parietal control network and default mode network.
Article
Neurosciences
Sandra Martin, Kathleen A. Williams, Dorothee Saur, Gesa Hartwigsen
Summary: This neuroimaging study reveals widespread neural reorganization processes in the aging brain and investigates the behavioral impact of this reorganization. The findings show that older adults experience large-scale network reorganization even when their word retrieval abilities are intact.
Article
Radiology, Nuclear Medicine & Medical Imaging
Sabrina Katzdobler, Alexander Nitschmann, Henryk Barthel, Gerard Bischof, Leonie Beyer, Ken Marek, Mengmeng Song, Olivia Wagemann, Carla Palleis, Endy Weidinger, Anne Nack, Urban Fietzek, Carolin Kurz, Jan Haeckert, Theresa Stapf, Christian Ferschmann, Maximilian Scheifele, Florian Eckenweber, Gloria Biechele, Nicolai Franzmeier, Anna Dewenter, Sonja Schoenecker, Dorothee Saur, Matthias L. Schroeter, Jost-Julian Rumpf, Michael Rullmann, Andreas Schildan, Marianne Patt, Andrew W. Stephens, Thilo van Eimeren, Bernd Neumaier, Alexander Drzezga, Adrian Danek, Joseph Classen, Katharina Buerger, Daniel Janowitz, Boris-Stephan Rauchmann, Sophia Stoecklein, Robert Perneczky, Florian Schoeberl, Andreas Zwergal, Gunter U. Hoeglinger, Peter Bartenstein, Victor Villemagne, John Seibyl, Osama Sabri, Johannes Levin, Matthias Brendel
Summary: Early-phase [F-18]PI-2620 PET can be used for regional assessment of neuronal injury in neurodegenerative diseases, while standard late-phase [F-18]PI-2620 tau-PET is able to discriminate 4RTs from controls. This study investigated the additive value of early-phase [F-18]PI-2620 PET for biomarker-based evaluation of 4RTs.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2023)
Article
Clinical Neurology
Anika Stockert, Sophia Hormig-Rauber, Max Wawrzyniak, Julian Klingbeil, Hans Ralf Schneider, Mandy Pirlich, Stefan Schob, Karl-Titus Hoffmann, Dorothee Saur
Summary: This study investigated the relationship between thalamic stroke and aphasia by examining the integration of the thalamus into cortical networks. The results showed a correlation between lesions in the thalamus and language impairments, suggesting that dysfunction in thalamocortical networks may contribute to thalamic aphasia.
Article
Clinical Neurology
Jonas A. Hosp, Andrea Dressing, Anika Engesser, Volkmar Glauche, Dorothee Kummerer, Ema B. Vaidelyte, Mariachristina Musso, Michel Rijntjes, Cornelius Weiller
Summary: This study explores the role of the dopaminergic ventral tegmental midbrain nuclei-motor cortex (VTMC) tract in post-stroke recovery. The study found that both the VTMC tract and the corticospinal tract (CST) degenerate after stroke, but only the degeneration of the VTMC tract is associated with lesion size. Regression analysis showed that changes in VTMC tract integrity are more strongly related to independence in daily activities, upper limb motor impairment, and cortical symptoms compared to CST, which is mainly associated with the degree of hemiparesis.
ANNALS OF NEUROLOGY
(2023)
Article
Neurosciences
Mariacristina Musso, Eckart Altenmueller, Marco Reisert, Jonas Hosp, Ralf Schwarzwald, Bettina Blank, Julian Horn, Volkmar Glauche, Christoph Kaller, Cornelius Weiller, Martin Schumacher
Summary: Conducting is a well-structured system used to convey information about the rhythm and dynamic of a musical piece. Conductors communicate the musical tempo to the orchestra, creating a unified and expressive musical gestalt. This study found that conducting activates specific regions of the brain, including the supplementary and premotor cortex, superior temporal gyrus, and Broca's area, which are involved in sensorimotor mapping and language processing.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2023)
Editorial Material
Clinical Neurology
Cornelius Weiller, Michel Rijntjes
Editorial Material
Clinical Neurology
Dorothee Saur
Editorial Material
Clinical Neurology
Julian Klingbeil, Dorothee Saur
Article
Clinical Neurology
Hannah Rosenzopf, Julian Klingbeil, Max Wawrzyniak, Lisa Roehrig, Christoph Sperber, Dorothee Saur, Hans-Otto Karnath
Summary: Rosenzopf et al. study the network changes in 'pusher syndrome' caused by unilateral stroke. They find that pusher syndrome is a result of direct damage or disconnection of the posterior thalamus. Functional and structural connectivity analyses show that pusher syndrome patients with thalamic lesions have cortical diaschisis and pusher patients with cortical stroke have disconnectivity to the posterior thalamus caused by accompanying white matter damage. These findings provide evidence for thalamo-cortical interconnection and explain the location of thalamo-cortical disconnections in pusher syndrome.
Article
Clinical Neurology
Florian Welle, Kristin Stoll, Christina Gillmann, Jeanette Henkelmann, Gordian Prasse, Daniel P. O. Kaiser, Elias Kellner, Marco Reisert, Hans R. Schneider, Julian Klingbeil, Anika Stockert, Donald Lobsien, Karl-Titus Hoffmann, Dorothee Saur, Max Wawrzyniak
Summary: Perfusion CT is used for selecting patients with proximal intracranial vessel occlusion for thrombectomy in the extended time window, and our multiparametric logistic model shows potential in tissue outcome prediction. By utilizing perfusion parameter maps, our logistic model demonstrates comparable volumetric accuracy and superior topographical accuracy compared to single-parameter thresholding-based models. The combination of tissue and functional outcome prediction may provide personalized biomarkers for the benefit of mechanical thrombectomy in acute stroke care.
TRANSLATIONAL STROKE RESEARCH
(2023)
Article
Clinical Neurology
Julian Klingbeil, Max-Lennart Brandt, Anika Stockert, Petra Baum, Karl-Titus Hoffmann, Dorothee Saur, Max Wawrzyniak
Summary: The study found that post-stroke depressive symptoms (PSDS) are common and associated with specific lesion locations in the brain, such as the right insula, right putamen, inferior frontal gyrus, and right amygdala. Structural disconnection in the right temporal lobe was also found to be associated with depressive symptoms. However, no association was found with localized functional diaschisis.
FRONTIERS IN NEUROLOGY
(2023)
Article
Clinical Neurology
Nils Schroeter, Tobias Bormann, Michel Rijntjes, Ganna Blazhenets, Raissa Berti, Bastian E. A. Sajonz, Horst Urbach, Cornelius Weiller, Philipp T. Meyer, Alexander Rau, Lars Frings
Summary: This study suggests that microangiopathic white matter lesions do not have a significant impact on neurocognitive performance in Parkinson's disease, while neuronal dysfunction does.
MOVEMENT DISORDERS CLINICAL PRACTICE
(2023)
Article
Clinical Neurology
Sandra Martin, Regine Frieling, Dorothee Saur, Gesa Hartwigsen
Summary: This study investigated the potential of intermittent theta-burst stimulation (iTBS) to enhance executive and semantic processing. The results showed that effective stimulation increased activity during semantic processing and reduced overall connectivity between domain-general networks. Moreover, the changes induced by stimulation were linked to more efficient semantic processing.
Article
Radiology, Nuclear Medicine & Medical Imaging
Alexander Rau, Nils Schroeter, Michel Rijntjes, Fabian Bamberg, Wolfgang H. H. Jost, Maxim Zaitsev, Cornelius Weiller, Stephan Rau, Horst Urbach, Marco Reisert, Maximilian F. F. Russe
Summary: This study compared the performance of a Deep Neural Patchwork (DNP) with other established segmentation algorithms in accurately delineating atrophic structures in multiple system atrophy (MSA), Parkinson's disease (PD), and healthy controls. The results showed that DNP had significantly better performance in delineating the putamen compared to other algorithms, and it also demonstrated superior diagnostic accuracy in distinguishing MSA, PD, and healthy controls.
EUROPEAN RADIOLOGY
(2023)
Article
Clinical Neurology
Anika Stockert, Sophia Hormig-Rauber, Max Wawrzyniak, Julian Klingbeil, Hans Ralf Schneider, Mandy Pirlich, Stefan Schob, Karl-Titus Hoffmann, Dorothee Saur
Summary: Thalamic aphasia is associated with lesions in the left mediodorsal thalamic nucleus and functionally connected cortical language networks as well as bilateral cortical networks for cognitive control. Dysfunction in thalamocortical networks contributes to the development of thalamic aphasia, specifically due to inefficient integration between otherwise undamaged domain-general and language networks.
