Restoration of embryonic gene expression patterns in tissue regeneration and disease

YAP activates pancreatic stellate cells and enhances pancreatic fibrosis

(2022) Lennard Spanehl et al.   Hepatobiliary & Pancreatic Diseases International

Tracing colonic embryonic transcriptional profiles and their reactivation upon intestinal damage

(2021) Hassan Fazilaty et al.   Cell Reports

Regenerative lineages and immune-mediated pruning in lung cancer metastasis

(2020) Ashley M. Laughney et al.   NATURE MEDICINE

Fat1 deletion promotes hybrid EMT state, tumour stemness and metastasis

(2020) Ievgenia Pastushenko et al.   NATURE

Circulating Tumor Cell Clustering Shapes DNA Methylation to Enable Metastasis Seeding

(2019) Sofia Gkountela et al.   CELL

Yap/Taz regulate alveolar regeneration and resolution of lung inflammation

(2019) Ryan LaCanna et al.   JOURNAL OF CLINICAL INVESTIGATION

SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair

(2019) Qi Miao et al.   Nature Communications

Parasitic helminths induce fetal-like reversion in the intestinal stem cell niche

(2018) Ysbrand M. Nusse et al.   NATURE

EMT: 2016

(2016) M. Angela Nieto et al.   CELL

A Mammary Stem Cell Population Identified and Characterized in Late Embryogenesis Reveals Similarities to Human Breast Cancer

(2012) Benjamin T. Spike et al.   Cell Stem Cell