Bioactive C21 Steroidal Glycosides from Euphorbia kansui Promoted HepG2 Cell Apoptosis via the Degradation of ATP1A1 and Inhibited Macrophage Polarization under Co-Cultivation
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Title
Bioactive C21 Steroidal Glycosides from Euphorbia kansui Promoted HepG2 Cell Apoptosis via the Degradation of ATP1A1 and Inhibited Macrophage Polarization under Co-Cultivation
Authors
Keywords
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Journal
MOLECULES
Volume 28, Issue 6, Pages 2830
Publisher
MDPI AG
Online
2023-03-22
DOI
10.3390/molecules28062830
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- (2021) Shreya Das et al. APOPTOSIS
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- (2021) Yuan Si et al. Phytochemistry Letters
- Macrophage Polarization and Its Role in Liver Disease
- (2021) Cheng Wang et al. Frontiers in Immunology
- Na+/K+-ATPase-Targeted Cytotoxicity of (+)-Digoxin and Several Semisynthetic Derivatives
- (2020) Yulin Ren et al. JOURNAL OF NATURAL PRODUCTS
- Effect of the vinegar-process on chemical compositions and biological activities of Euphorbia kansui: A review
- (2020) Qiao Zhang et al. JOURNAL OF ETHNOPHARMACOLOGY
- Inhibitors of Na+/K+ ATPase exhibit antitumor effects on multicellular tumor spheroids of hepatocellular carcinoma
- (2020) Yeonhwa Song et al. Scientific Reports
- Diterpenoids from Euphorbia royleana reverse P-glycoprotein-mediated multidrug resistance in cancer cells
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- C21 Fraction Refined from Marsdenia tenacissima-Induced Apoptosis is Enhanced by Suppression of Autophagy in Human Gastric Cell Lines
- (2020) Kaiqiang Li et al. ACS Omega
- ATP1A1 Integrates AKT and ERK Signaling via Potential Interaction With Src to Promote Growth and Survival in Glioma Stem Cells
- (2019) Yang Yu et al. Frontiers in Oncology
- Neuroprotection of two C21 steroidal glycosides from Cynanchum auriculatum against H2O2-induced damage on PC12 cells
- (2019) Mi Zhang et al. NATURAL PRODUCT RESEARCH
- Hepatotoxicity evaluation of Euphorbia kansui on zebrafish larvae in vivo
- (2019) Chongjun Zhao et al. PHYTOMEDICINE
- Nitric oxide and tumor metabolic reprogramming
- (2019) Laura M. López-Sánchez et al. BIOCHEMICAL PHARMACOLOGY
- Conformational states of the pig kidney Na+/K+-ATPase differently affect bufadienolides and cardenolides: A directed structure-activity and structure-kinetics study
- (2019) Pedro Azalim et al. BIOCHEMICAL PHARMACOLOGY
- Regulation of ion transport from within ion transit pathways
- (2019) Donald W. Hilgemann JOURNAL OF GENERAL PHYSIOLOGY
- Carbonic anhydrase 2 inhibits epithelial–mesenchymal transition and metastasis in hepatocellular carcinoma
- (2018) Chenyue Zhang et al. CARCINOGENESIS
- HBeAg induces the expression of macrophage miR-155 to accelerate liver injury via promoting production of inflammatory cytokines
- (2018) Wenwen Wang et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Sodium chloride (NaCl) potentiates digoxin-induced anti-tumor activity in small cell lung cancer
- (2018) Ke Deng et al. CANCER BIOLOGY & THERAPY
- Characterization of Precursor-Dependent Steroidogenesis in Human Prostate Cancer Models
- (2018) Subrata Deb et al. Cancers
- Chemical Constituents from Euphorbia kansui
- (2017) Qiao Zhang et al. MOLECULES
- C 21 steroidal glycosides from Cynanchum auriculatum and their neuroprotective effects against H 2 O 2 -induced damage in PC12 cells
- (2017) Xicheng Qian et al. PHYTOCHEMISTRY
- C21 steroid-enriched fraction refined from Marsdenia tenacissima inhibits hepatocellular carcinoma through the coordination of Hippo-Yap and PTEN-PI3K/AKT signaling pathways
- (2017) Yu Zhang et al. Oncotarget
- The Chemical and Biological Properties of Euphorbia kansui
- (2016) Juan Shen et al. AMERICAN JOURNAL OF CHINESE MEDICINE
- The IL-6/gp130/STAT3 signaling axis: recent advances towards specific inhibition
- (2015) Christoph Garbers et al. CURRENT OPINION IN IMMUNOLOGY
- Metformin affects the features of a human hepatocellular cell line (HepG2) by regulating macrophage polarization in a co-culture microenviroment
- (2015) Miaojiao Chen et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- Na+/K+-ATPase α1 subunit, a novel therapeutic target for hepatocellular carcinoma
- (2015) Liping Zhuang et al. Oncotarget
- Ouabain-induced Internalization and Lysosomal Degradation of the Na+/K+-ATPase
- (2013) Marina Cherniavsky-Lev et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Antitumor activity of C-21 steroidal glycosides from Cynanchum auriculatum Royle ex Wight
- (2008) Yun-ru Peng et al. PHYTOMEDICINE
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