Journal
CEREBELLUM
Volume 16, Issue 5-6, Pages 877-879Publisher
SPRINGER
DOI: 10.1007/s12311-015-0663-y
Keywords
Ataxia; Purkinje cell; Calcium signaling; TRPC3; mGluR1
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Funding
- Wellcome Trust [084655] Funding Source: Medline
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The dominantly inherited cerebellar ataxias are a clinically and genetically heterogeneous group of neurodegenerative disorders. Studies using mouse models as well as recent genetic and transcriptomic human findings point to an important role for TRPC3 signaling in cerebellar ataxia.
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