Improving the production of 9α-hydroxy-4-androstene-3,17-dione from phytosterols by 3-ketosteroid-Δ1-dehydrogenase deletions and multiple genetic modifications in Mycobacterium fortuitum
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Improving the production of 9α-hydroxy-4-androstene-3,17-dione from phytosterols by 3-ketosteroid-Δ1-dehydrogenase deletions and multiple genetic modifications in Mycobacterium fortuitum
Authors
Keywords
-
Journal
Microbial Cell Factories
Volume 22, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2023-03-27
DOI
10.1186/s12934-023-02052-y
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Efficient conversion of phytosterols into 4-androstene-3,17-dione and its C1,2-dehydrogenized and 9α-hydroxylated derivatives by engineered Mycobacteria
- (2021) Xin Li et al. Microbial Cell Factories
- Biotransformation of Phytosterols to Androst-1,4-Diene-3,17-Dione by Mycobacterium sp. ZFZ Expressing 3-Ketosteroid-Δ1-Dehydrogenase
- (2020) Xiangcen Liu et al. Catalysts
- A Dual Role Reductase from Phytosterols Catabolism Enables the Efficient Production of Valuable Steroid Precursors
- (2020) Haidong Peng et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- The role and mechanism of microbial 3-ketosteroid Δ1-dehydrogenases in steroid breakdown
- (2019) Ali Rohman et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Genome-wide response on phytosterol in 9-hydroxyandrostenedione-producing strain of Mycobacterium sp. VKM Ac-1817D
- (2019) Eugeny Y. Bragin et al. BMC BIOTECHNOLOGY
- A Novel 3-Phytosterone-9α-Hydroxylase Oxygenation Component and Its Application in Bioconversion of 4-Androstene-3,17-Dione to 9α-Hydroxy-4-Androstene-3,17-Dione Coupling with A NADH Regeneration Formate Dehydrogenase
- (2019) Xian Zhang et al. MOLECULES
- Effects of a nonionic surfactant TX-40 on 9α-hydroxyandrost-4-ene-3,17-dione biosynthesis and physiological properties of Mycobacterium sp. LY-1
- (2019) Longfei Zhou et al. PROCESS BIOCHEMISTRY
- Identification, function, and application of 3-ketosteroid Δ1-dehydrogenase isozymes in Mycobacterium neoaurum DSM 1381 for the production of steroidic synthons
- (2018) Ruijie Zhang et al. Microbial Cell Factories
- Metagenomes Reveal Global Distribution of Bacterial Steroid Catabolism in Natural, Engineered, and Host Environments
- (2018) Johannes Holert et al. mBio
- New Insights on Steroid Biotechnology
- (2018) Lorena Fernández-Cabezón et al. Frontiers in Microbiology
- Enhancing Expression of 3-Ketosteroid-9α-Hydroxylase Oxygenase, an Enzyme with Broad Substrate Range and High Hydroxylation Ability, in Mycobacterium sp. LY-1
- (2018) Hui Li et al. APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY
- Functional differentiation of 3-ketosteroid Δ1-dehydrogenase isozymes in Rhodococcus ruber strain Chol-4
- (2017) Govinda Guevara et al. Microbial Cell Factories
- Efficient 9α-hydroxy-4-androstene-3,17-dione production by engineered Bacillus subtilis co-expressing Mycobacterium neoaurum 3-ketosteroid 9α-hydroxylase and B. subtilis glucose 1-dehydrogenase with NADH regeneration
- (2016) Xian Zhang et al. SpringerPlus
- EngineeringMycobacterium smegmatisfor testosterone production
- (2016) Lorena Fernández-Cabezón et al. Microbial Biotechnology
- Mycobacterium smegmatisis a suitable cell factory for the production of steroidic synthons
- (2016) Beatriz Galán et al. Microbial Biotechnology
- Unraveling and engineering the production of 23,24-bisnorcholenic steroids in sterol metabolism
- (2016) Li-Qin Xu et al. Scientific Reports
- Genetic differences in ksdD influence on the ADD/AD ratio of Mycobacterium neoaurum
- (2015) Rili Xie et al. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY
- Characterization and engineering of 3-ketosteroid-△1-dehydrogenase and 3-ketosteroid-9α-hydroxylase in Mycobacterium neoaurum ATCC 25795 to produce 9α-hydroxy-4-androstene-3,17-dione through the catabolism of sterols
- (2014) Kang Yao et al. METABOLIC ENGINEERING
- Crystal Structure and Site-directed Mutagenesis of 3-Ketosteroid Δ1-Dehydrogenase fromRhodococcus erythropolisSQ1 Explain Its Catalytic Mechanism
- (2013) Ali Rohman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Molecular characterization of three 3-ketosteroid-Δ1-dehydrogenase isoenzymes of Rhodococcus ruber strain Chol-4
- (2012) Laura Fernández de las Heras et al. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY
- Identification and engineering of cholesterol oxidases involved in the initial step of sterols catabolism in Mycobacterium neoaurum
- (2012) Kang Yao et al. METABOLIC ENGINEERING
- Catabolism and biotechnological applications of cholesterol degrading bacteria
- (2012) J. L. García et al. Microbial Biotechnology
- Mycobacterium tuberculosis Is Able To Accumulate and Utilize Cholesterol
- (2009) A. Brzostek et al. JOURNAL OF BACTERIOLOGY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started