Patient-derived xenografts faithfully replicated clinical outcome in a phase II co-clinical trial of arsenic trioxide in relapsed small cell lung cancer

Small-Molecule Bcl2 BH4 Antagonist for Lung Cancer Therapy

(2015) Bingshe Han et al.   CANCER CELL

DNA methylation in small cell lung cancer defines distinct disease subtypes and correlates with high expression of EZH2

(2015) J T Poirier et al.   ONCOGENE

Initiation and Characterization of Small Cell Lung Cancer Patient-Derived Xenografts from Ultrasound-Guided Transbronchial Needle Aspirates

(2015) Wade C. Anderson et al.   PLoS One

Comparison of Newly Diagnosed and Relapsed Patients with Acute Promyelocytic Leukemia Treated with Arsenic Trioxide: Insight into Mechanisms of Resistance

(2015) Ezhilarasi Chendamarai et al.   PLoS One

Cancer statistics, 2014

(2014) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Arsenic Trioxide Exerts Anti-lung Cancer Activity by Inhibiting Angiogenesis

(2014) Meng-Hang Yang et al.   CURRENT CANCER DRUG TARGETS

Tumorigenicity and genetic profiling of circulating tumor cells in small-cell lung cancer

(2014) Cassandra L Hodgkinson et al.   NATURE MEDICINE

Pharmacogenomic Approach to Identify Drug Sensitivity in Small-Cell Lung Cancer

(2014) Gary Wildey et al.   PLoS One

Genomic Characterisation of Small Cell Lung Cancer Patient-Derived Xenografts Generated from Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration Specimens

(2014) Tracy L. Leong et al.   PLoS One

Combined arsenic trioxide-cisplatin treatment enhances apoptosis in oral squamous cell carcinoma cells

(2014) Toshiki Nakaoka et al.   CELLULAR ONCOLOGY

Poly (ADP) ribose polymerase enzyme inhibitor, veliparib, potentiates chemotherapy and radiation in vitro and in vivo in small cell lung cancer

(2014) Taofeek K. Owonikoko et al.   Cancer Medicine

Chemotherapy for small-cell lung cancer

(2013) Gregory P Kalemkerian   LANCET ONCOLOGY

Combination of arsenic trioxide and chemotherapy in small cell lung cancer

(2013) Chun-yan Zheng et al.   LUNG CANCER

Small Cell Lung Cancer: Therapies and Targets

(2013) Rathi N. Pillai et al.   SEMINARS IN ONCOLOGY

Subpopulation of small-cell lung cancer cells expressing CD133 and CD87 show resistance to chemotherapy

(2012) Toshio Kubo et al.   CANCER SCIENCE

A Systematic Analysis of Efficacy of Second-Line Chemotherapy in Sensitive and Refractory Small-Cell Lung Cancer

(2012) Taofeek K. Owonikoko et al.   Journal of Thoracic Oncology

A Platform for Rapid Detection of Multiple Oncogenic Mutations With Relevance to Targeted Therapy in Non–Small-Cell Lung Cancer

(2011) Zengliu Su et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Phase II Study of Amrubicin As Second-Line Therapy in Patients With Platinum-Refractory Small-Cell Lung Cancer

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Clinical relevance of human cancer xenografts as a tool for preclinical assessment: example of in-vivo evaluation of topotecan-based chemotherapy in a panel of human small-cell lung cancer xenografts

(2009) Fariba Némati et al.   ANTI-CANCER DRUGS

Arsenic trioxide and cisplatin synergism increase cytotoxicity in human ovarian cancer cells: Therapeutic potential for ovarian cancer

(2009) Ning Zhang et al.   CANCER SCIENCE

Arsenic trioxide exerts synergistic effects with cisplatin on non-small cell lung cancer cells via apoptosis induction

(2009) Hecheng Li et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Arsenic trioxide is highly cytotoxic to small cell lung carcinoma cells

(2009) H. M. Pettersson et al.   MOLECULAR CANCER THERAPEUTICS

Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment

(2009) G. Bertolini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Safety and efficacy of arsenic trioxide for patients with advanced metastatic melanoma

(2008) Ahmad A. Tarhini et al.   CANCER

Phase 1 trial and pharmacokinetic study of arsenic trioxide in children and adolescents with refractory or relapsed acute leukemia, including acute promyelocytic leukemia or lymphoma

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