Enantioselective Total Synthesis of (+)-Stephadiamine

Taming the radical cation intermediate enabled one-step access to structurally diverse lignans

(2022) Jia-Chen Xiang et al.   Nature Communications

Synthesis of 3-Acyloxyindolenines by TiCl3-Mediated Reductive Cyclization of 2-(ortho-Nitroaryl)-Substituted Enol Esters

(2022) Dina V. Boyarskaya et al.   ORGANIC LETTERS

Asymmetric Total Synthesis of Hasubanan Alkaloids: Periglaucines A–C, N,O ‐Dimethyloxostephine and Oxostephabenine

(2022) Shaolei Ding et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Unified divergent strategy towards the total synthesis of the three sub-classes of hasubanan alkaloids

(2021) Guang Li et al.   Nature Communications

Enantioselective Total Synthesis of (+)-Stephadiamine through Bioinspired Aza-Benzilic Acid Type Rearrangement

(2021) Minami Odagi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Enantioselective Synthesis of Morpholinones Enabled by Aza-Benzilic Ester Rearrangement

(2021) Yu-Ping He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nitrone Formation by Reaction of an Enolate with a Nitro Group

(2021) Hiroaki Shimizu et al.   ORGANIC LETTERS

Enantioselective Total Synthesis of Cepharatines via Bioinspired Ring Reconstruction

(2021) Minami Odagi et al.   JOURNAL OF ORGANIC CHEMISTRY

TiCl3‐Mediated Synthesis of 2,3,3‐Trisubstituted Indolenines: Total Synthesis of (+)‐1,2‐Dehydroaspidospermidine, (+)‐Condyfoline and (‐)‐Tubifoline

(2020) Bastien Delayre et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Formal synthesis of cochlearol A, a meroterpenoid with renoprotective activity

(2020) Kazumi Naruse et al.   TETRAHEDRON LETTERS

Evaluation of Manassantin A Tetrahydrofuran Core Region Analogues and Cooperative Therapeutic Effects with EGFR Inhibition

(2020) Seung-Hwa Kwak et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Transformations of Nitrones for Organic Synthesis

(2019) Shun-Ichi Murahashi et al.   CHEMICAL REVIEWS

Site-Selective Alkoxylation of Benzylic C−H Bonds by Photoredox Catalysis

(2019) Byung Joo Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent advances in the application of Diels–Alder reactions involving o-quinodimethanes, aza-o-quinone methides and o-quinone methides in natural product total synthesis

(2018) Baochao Yang et al.   CHEMICAL SOCIETY REVIEWS

Total Synthesis of the Norhasubanan Alkaloid Stephadiamine

(2018) Nina Hartrampf et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Curtius rearrangement: mechanistic insight and recent applications in natural product syntheses

(2018) Arun K. Ghosh et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Metamorphosis of cycloalkenes for the divergent total synthesis of polycyclic indole alkaloids

(2018) Zhengren Xu et al.   CHEMICAL SOCIETY REVIEWS

Memory of Chirality in Bromoalkyne Carbocyclization: Applications in Asymmetric Total Synthesis of Hasubanan Alkaloids

(2018) Shenpeng Tan et al.   ORGANIC LETTERS

Enantioselective Synthesis and Racemization of (−)-Sinoracutine

(2016) Giulio Volpin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Convergent and Biomimetic Enantioselective Total Synthesis of (−)-Communesin F

(2016) Stephen P. Lathrop et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthetic approaches towards alkaloids bearing α-tertiary amines

(2016) Anastasia Hager et al.   NATURAL PRODUCT REPORTS

Asymmetric Dearomatization of β-Naphthols through a Bifunctional-Thiourea-Catalyzed Michael Reaction

(2015) Shou-Guo Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aqueous Titanium Trichloride Promoted Reductive Cyclization ofo-Nitrostyrenes to Indoles: Development and Application to the Synthesis of Rizatriptan and Aspidospermidine

(2015) Shuo Tong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Total Syntheses of (−)-Mersicarpine, (−)-Scholarisine G, (+)-Melodinine E, (−)-Leuconoxine, (−)-Leuconolam, (−)-Leuconodine A, (+)-Leuconodine F, and (−)-Leuconodine C: Self-Induced Diastereomeric Anisochronism (SIDA) Phenomenon for Scholarisine G and Leuconodines A and C

(2015) Zhengren Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Copper(I/II)-Catalyzed Conjugate Addition of Nitro Esters to β,γ-Unsaturated α-Ketoesters

(2014) Sheng Zhang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Substrate-Modified Functional Group Reactivity: Hasubanan and Acutumine Alkaloid Syntheses

(2014) Sandra M. King et al.   JOURNAL OF ORGANIC CHEMISTRY

Unified Strategy to Monoterpene Indole Alkaloids: Total Syntheses of (±)-Goniomitine, (±)-1,2-Dehydroaspidospermidine, (±)-Aspidospermidine, (±)-Vincadifformine, and (±)-Kopsihainanine A

(2014) Olivier Wagnières et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Development of Enantioselective Synthetic Routes to the Hasubanan and Acutumine Alkaloids

(2013) Nicholas A. Calandra et al.   JOURNAL OF ORGANIC CHEMISTRY

Concise Synthesis of the Hasubanan Alkaloid (±)-Cepharatine A Using a Suzuki Coupling Reaction To Effect o,p-Phenolic Coupling

(2013) Philip Magnus et al.   ORGANIC LETTERS

One-pot access to 2-naphthols and benzofurans via the aerobic Wacker-type oxidation/intramolecular aldol cyclization

(2012) Meng-Yang Chang et al.   TETRAHEDRON

Efficient Entry to the Hasubanan Alkaloids: First Enantioselective Total Syntheses of (−)-Hasubanonine, (−)-Runanine, (−)-Delavayine, and (+)-Periglaucine B

(2011) Seth B. Herzon et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Short, Enantioselective Total Syntheses of (−)-8-Demethoxyrunanine and (−)-Cepharatines A, C, and D

(2011) Kangway V. Chuang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Water-compatible one-pot organocatalytic asymmetric synthesis of cyclic nitrones. Application in intramolecular 1,3-dipolar cycloadditions

(2011) David Sádaba et al.   TETRAHEDRON LETTERS

Synthesis of Chiral Cyclic Nitrones by Asymmetric Addition of β-Ketosulfones to Nitroalkenes followed by Reductive Cyclization

(2010) Olga García Mancheño et al.   CHEMISTRY-A EUROPEAN JOURNAL

Hasubanan Alkaloids with δ-Opioid Binding Affinity from the Aerial Parts ofStephania japonica

(2010) Anthony R. Carroll et al.   JOURNAL OF NATURAL PRODUCTS

Antimicrobial Hasubanalactam Alkaloid fromStephania glabra

(2009) Deepak Semwal et al.   PLANTA MEDICA

Periglaucines A−D, Anti-HBV and -HIV-1 Alkaloids fromPericampylus glaucus

(2008) Meng-Hong Yan et al.   JOURNAL OF NATURAL PRODUCTS

Synthesis of the Common Propellane Core Structure of the Hasubanan Alkaloids

(2008) Thong X. Nguyen et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of Isohasubanan Alkaloids via Enantioselective Ketone Allylation and Discovery of an Unexpected Rearrangement

(2008) Daniel K. Nielsen et al.   JOURNAL OF ORGANIC CHEMISTRY

Development of Pharmaceutical Drugs, Drug Intermediates and Ingredients by Using Direct Organo-Click Reactions

(2007) Dhevalapally B. Ramachary et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY