Exome sequencing identifies a mutation in TMC1 as a novel cause of autosomal recessive nonsyndromic hearing loss

Mutations of TMC1 cause deafness by disrupting mechanoelectrical transduction

(2014) Hiroshi Nakanishi et al.   AURIS NASUS LARYNX

A Novel DFNA36 Mutation in TMC1 Orthologous to the Beethoven (Bth) Mouse Associated with Autosomal Dominant Hearing Loss in a Chinese Family

(2014) Yali Zhao et al.   PLoS One

The role of transmembrane channel–like proteins in the operation of hair cell mechanotransducer channels

(2013) Kyunghee X. Kim et al.   JOURNAL OF GENERAL PHYSIOLOGY

tmc-1 encodes a sodium-sensitive channel required for salt chemosensation in C. elegans

(2013) Marios Chatzigeorgiou et al.   NATURE

TMC1 and TMC2 Are Components of the Mechanotransduction Channel in Hair Cells of the Mammalian Inner Ear

(2013) Bifeng Pan et al.   NEURON

Cochlear Implants — Science, Serendipity, and Success

(2013) Gerard O'Donoghue   NEW ENGLAND JOURNAL OF MEDICINE

Novel Compound Heterozygous TMC1 Mutations Associated with Autosomal Recessive Hearing Loss in a Chinese Family

(2013) Xue Gao et al.   PLoS One

High-throughput sequencing to decipher the genetic heterogeneity of deafness

(2012) Zippora Brownstein et al.   GENOME BIOLOGY

Mechanotransduction in mouse inner ear hair cells requires transmembrane channel–like genes

(2011) Yoshiyuki Kawashima et al.   JOURNAL OF CLINICAL INVESTIGATION

Topology of Transmembrane Channel-like Gene 1 Protein

(2010) Valentina Labay et al.   BIOCHEMISTRY

High Frequency of the p.R34X Mutation in the TMC1 Gene Associated with Nonsyndromic Hearing Loss Is Due to Founder Effects

(2010) Mariem Ben Saïd et al.   Genetic Testing and Molecular Biomarkers

MutationTaster evaluates disease-causing potential of sequence alterations

(2010) Jana Marie Schwarz et al.   NATURE METHODS