Improved calvarial bone repair by hASCs engineered with Cre/loxP-based baculovirus conferring prolonged BMP-2 and MiR-148b co-expression

Healing of osteoporotic bone defects by baculovirus-engineered bone marrow-derived MSCs expressing MicroRNA sponges

(2016) Kuei-Chang Li et al.   BIOMATERIALS

Photoactivated miR-148b–nanoparticle conjugates improve closure of critical size mouse calvarial defects

(2015) Ammar T. Qureshi et al.   Acta Biomaterialia

Nanoparticle delivery of stable miR-199a-5p agomir improves the osteogenesis of human mesenchymal stem cells via the HIF1a pathway

(2015) Xiao Chen et al.   BIOMATERIALS

Healing of massive segmental femoral bone defects in minipigs by allogenic ASCs engineered with FLPo/Frt-based baculovirus vectors

(2015) Chin-Yu Lin et al.   BIOMATERIALS

Biomaterials mediated microRNA delivery for bone tissue engineering

(2015) M. Sriram et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

MiR-26a Rescues Bone Regeneration Deficiency of Mesenchymal Stem Cells Derived From Osteoporotic Mice

(2015) Yan Li et al.   MOLECULAR THERAPY

Baculovirus-Mediated miRNA Regulation to Suppress Hepatocellular Carcinoma Tumorigenicity and Metastasis

(2015) Chiu-Ling Chen et al.   MOLECULAR THERAPY

Osteogenic differentiation of adipose-derived stem cells and calvarial defect repair using baculovirus-mediated co-expression of BMP-2 and miR-148b

(2014) Ya-Hsin Liao et al.   BIOMATERIALS

Non-viral oligonucleotide antimiR-138 delivery to mesenchymal stem cell sheets and the effect on osteogenesis

(2014) Jun Yan et al.   BIOMATERIALS

Biosafety Challenges for Use of Lentiviral Vectors in Gene Therapy

(2014) Michael Rothe et al.   CURRENT GENE THERAPY

Role of miRNAs in bone and their potential as therapeutic targets

(2014) Kyoung Min Kim et al.   CURRENT OPINION IN PHARMACOLOGY

Uncovering and Dissecting the Genotoxicity of Self-inactivating Lentiviral Vectors In Vivo

(2014) Daniela Cesana et al.   MOLECULAR THERAPY

Efficient gene delivery into cell lines and stem cells using baculovirus

(2014) Li-Yu Sung et al.   Nature Protocols

Altered p53 regulation of miR-148b and p55PIK contributes to tumor progression in colorectal cancer

(2014) G Wang et al.   ONCOGENE

Combinatorial Gene Therapy Accelerates Bone Regeneration: Non-Viral Dual Delivery of VEGF and BMP2 in a Collagen-Nanohydroxyapatite Scaffold

(2014) Caroline M. Curtin et al.   Advanced Healthcare Materials

The role of miR-31-modified adipose tissue-derived stem cells in repairing rat critical-sized calvarial defects

(2013) Yuan Deng et al.   BIOMATERIALS

The use of ASCs engineered to express BMP2 or TGF-β3 within scaffold constructs to promote calvarial bone repair

(2013) Chin-Yu Lin et al.   BIOMATERIALS

The promotion of bone regeneration through positive regulation of angiogenic–osteogenic coupling using microRNA-26a

(2013) Yan Li et al.   BIOMATERIALS

miR-148b–Nanoparticle conjugates for light mediated osteogenesis of human adipose stromal/stem cells

(2013) Ammar T. Qureshi et al.   BIOMATERIALS

Baculovirus-transduced, VEGF-expressing adipose-derived stem cell sheet for the treatment of myocardium infarction

(2013) Tsung-Szu Yeh et al.   BIOMATERIALS

Recent progresses in gene delivery-based bone tissue engineering

(2013) Chia-Hsin Lu et al.   BIOTECHNOLOGY ADVANCES

The MicroRNA-148/152 Family: Multi-faceted Players

(2013) Yue Chen et al.   Molecular Cancer

Baculovirus: an Insect-derived Vector for Diverse Gene Transfer Applications

(2013) Kari J Airenne et al.   MOLECULAR THERAPY

Regenerating Cartilages by Engineered ASCs: Prolonged TGF-β3/BMP-6 Expression Improved Articular Cartilage Formation and Restored Zonal Structure

(2013) Chia-Hsin Lu et al.   MOLECULAR THERAPY

Enhanced and prolonged baculovirus-mediated expression by incorporating recombinase system and in cis elements: a comparative study

(2013) Li-Yu Sung et al.   NUCLEIC ACIDS RESEARCH

Enhanced Osteogenesis of Adipose Derived Stem Cells with Noggin Suppression and Delivery of BMP-2

(2013) Jiabing Fan et al.   PLoS One

Augmented healing of critical-size calvarial defects by baculovirus-engineered MSCs that persistently express growth factors

(2012) Chin-Yu Lin et al.   BIOMATERIALS

miR148b is a major coordinator of breast cancer progression in a relapse-associated microRNA signature by targeting ITGA5, ROCK1, PIK3CA, NRAS, and CSF1

(2012) Daniela Cimino et al.   FASEB JOURNAL

MicroRNA control of bone formation and homeostasis

(2012) Jane B. Lian et al.   Nature Reviews Endocrinology

Repairing critical-sized calvarial defects with BMSCs modified by a constitutively active form of hypoxia-inducible factor-1α and a phosphate cement scaffold

(2011) Duohong Zou et al.   BIOMATERIALS

The role of adipose-derived stem cells engineered with the persistently expressing hybrid baculovirus in the healing of massive bone defects

(2011) Chin-Yu Lin et al.   BIOMATERIALS

Blood vessel formation in the tissue-engineered bone with the constitutively active form of HIF-1α mediated BMSCs

(2011) Duohong Zou et al.   BIOMATERIALS

Development of hybrid baculovirus vectors for artificial MicroRNA delivery and prolonged gene suppression

(2011) Chiu-Ling Chen et al.   BIOTECHNOLOGY AND BIOENGINEERING

MicroRNA-148b suppresses cell growth by targeting cholecystokinin-2 receptor in colorectal cancer

(2011) Yongxi Song et al.   INTERNATIONAL JOURNAL OF CANCER

Dura Mater Stimulates Human Adipose-Derived Stromal Cells to Undergo Bone Formation in Mouse Calvarial Defects

(2011) Benjamin Levi et al.   STEM CELLS

The healing of critical-sized femoral segmental bone defects in rabbits using baculovirus-engineered mesenchymal stem cells

(2010) Chin-Yu Lin et al.   BIOMATERIALS

MicroRNA-148/152 Impair Innate Response and Antigen Presentation of TLR-Triggered Dendritic Cells by Targeting CaMKII 

(2010) X. Liu et al.   JOURNAL OF IMMUNOLOGY

Cranial bone defects: current and future strategies

(2010) Caroline Szpalski et al.   Neurosurgical Focus

Human Adipose Derived Stromal Cells Heal Critical Size Mouse Calvarial Defects

(2010) Benjamin Levi et al.   PLoS One

RNA interference for noggin enhances the biological activity of bone morphogenetic proteins in vivo and in vitro

(2009) Kazushi Takayama et al.   JOURNAL OF BONE AND MINERAL METABOLISM

Development of a Hybrid Baculoviral Vector for Sustained Transgene Expression

(2009) Wen-Hsin Lo et al.   MOLECULAR THERAPY

Functional Profiling Reveals Critical Role for miRNA in Differentiation of Human Mesenchymal Stem Cells

(2009) Angela Schoolmeesters et al.   PLoS One

Xenotransplantation of Human Mesenchymal Stem Cells into Immunocompetent Rats for Calvarial Bone Repair

(2009) Ching-Kuang Chuang et al.   TISSUE ENGINEERING PART A