When and how to use antidotes for the reversal of direct oral anticoagulants: guidance from the SSC of the ISTH

Antidotes for Novel Oral Anticoagulants

(2015) Mark Crowther et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Nonclinical Safety Assessment of PER977

(2015) Dexter W. Sullivan et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Anticoagulation therapy in 2015: where we are and where we are going

(2015) Jeffrey I. Weitz   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

Safety, tolerability, and efficacy of idarucizumab for the reversal of the anticoagulant effect of dabigatran in healthy male volunteers: a randomised, placebo-controlled, double-blind phase 1 trial

(2015) Stephan Glund et al.   LANCET

Idarucizumab for Dabigatran Reversal

(2015) Charles V. Pollack et al.   NEW ENGLAND JOURNAL OF MEDICINE

Andexanet Alfa for the Reversal of Factor Xa Inhibitor Activity

(2015) Deborah M. Siegal et al.   NEW ENGLAND JOURNAL OF MEDICINE

Design and rationale for RE-VERSE AD: A phase 3 study of idarucizumab, a specific reversal agent for dabigatran

(2015) Paul A. Reilly et al.   THROMBOSIS AND HAEMOSTASIS

Laboratory Measurement of the Anticoagulant Activity of the Non–Vitamin K Oral Anticoagulants

(2014) Adam Cuker et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Use of PER977 to Reverse the Anticoagulant Effect of Edoxaban

(2014) Jack E. Ansell et al.   NEW ENGLAND JOURNAL OF MEDICINE

Management and Outcomes of Major Bleeding During Treatment With Dabigatran or Warfarin

(2013) Ammar Majeed et al.   CIRCULATION

Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials

(2013) Christian T Ruff et al.   LANCET

Evaluation of the anti-factor Xa chromogenic assay for the measurement of rivaroxaban plasma concentrations using calibrators and controls

(2011) Genevieve Contant et al.   THROMBOSIS AND HAEMOSTASIS

Dabigatran etexilate – a novel, reversible, oral direct thrombin inhibitor: Interpretation of coagulation assays and reversal of anticoagulant activity

(2010) Joachim Stangier et al.   THROMBOSIS AND HAEMOSTASIS