Network pharmacology and molecular docking reveal the immunomodulatory mechanism of rhubarb peony decoction for the treatment of ulcerative colitis and irritable bowel syndrome

Ibrutinib attenuated DSS-induced ulcerative colitis, oxidative stress, and inflammatory cascade by modulating PI3K/Akt and JNK/NFκB pathways

(2022) Liangliang Hao et al.   Archives of Medical Science

Aloe vera mitigates dextran sulfate sodium-induced rat ulcerative colitis by potentiating colon mucus barrier

(2021) Gaofeng Shi et al.   JOURNAL OF ETHNOPHARMACOLOGY

Molecular Targets and Mechanisms of Scutellariae radix-Coptidis rhizoma Drug Pair for the Treatment of Ulcerative Colitis Based on Network Pharmacology and Molecular Docking

(2021) Kai Niu et al.   Evidence-based Complementary and Alternative Medicine

Kaempferol Alleviates Murine Experimental Colitis by Restoring Gut Microbiota and Inhibiting the LPS-TLR4-NF-κB Axis

(2021) Yifan Qu et al.   Frontiers in Immunology

Advances in the study of emodin: an update on pharmacological properties and mechanistic basis

(2021) Qi Zheng et al.   Chinese Medicine

Irritable Bowel Syndrome and Neurological Deficiencies: Is There A Relationship? The Possible Relevance of the Oxidative Stress Status

(2020) Ioana-Miruna Balmus et al.   Medicina-Lithuania

Global burden of irritable bowel syndrome: trends, predictions and risk factors

(2020) Christopher J. Black et al.   Nature Reviews Gastroenterology & Hepatology

Irritable bowel syndrome

(2020) Alexander C Ford et al.   LANCET

Mechanisms of Disease: Inflammatory Bowel Diseases

(2019) Guilherme Piovezani Ramos et al.   MAYO CLINIC PROCEEDINGS

Dietary Quercetin Increases Colonic Microbial Diversity and Attenuates Colitis Severity in Citrobacter rodentium-Infected Mice

(2019) Rui Lin et al.   Frontiers in Microbiology

Medical Management of Inflammatory Bowel Disease

(2019) Derrick D. Eichele et al.   SURGICAL CLINICS OF NORTH AMERICA

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(2019) Andrew Canakis et al.   Current Opinion in Endocrinology Diabetes and Obesity

Evaluation of AutoDock and AutoDock Vina on the CASF-2013 benchmark

(2018) Thomas Gaillard   Journal of Chemical Information and Modeling

The Role of Catechins in Cellular Responses to Oxidative Stress

(2018) Jurga Bernatoniene et al.   MOLECULES

Are personalized tongxie formula based on diagnostic analyses more effective in reducing IBS symptoms?—A randomized controlled trial

(2018) Yuanyuan Wang et al.   COMPLEMENTARY THERAPIES IN MEDICINE

Close interplay of nitro-oxidative stress, advanced glycation end products and inflammation in inflammatory bowel diseases

(2018) Fabiana Andrea Moura et al.   CURRENT MEDICINAL CHEMISTRY

Rhubarb Peony Decoction Ameliorates Ulcerative Colitis in Mice by Regulating Gut Microbiota to Restoring Th17/Treg Balance

(2018) Shuang Luo et al.   JOURNAL OF ETHNOPHARMACOLOGY

Evaluation of the influence of mirabilite on the absorption and pharmacokinetics of the ingredients in Dahuang-mudan decoction by a validated UPLC/QTOF-MS/MS method

(2018) Feifei Nong et al.   BIOMEDICAL CHROMATOGRAPHY

Identification of β-Sitosterol as in Vitro Anti-Inflammatory Constituent in Moringa oleifera

(2018) Pei-Chun Liao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

β‐Sitosterol improves experimental colitis in mice with a target against pathogenic bacteria

(2018) Kang Ding et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Irritable Bowel Syndrome

(2018) Nuha Alammar et al.   MEDICAL CLINICS OF NORTH AMERICA

ETCM: an encyclopaedia of traditional Chinese medicine

(2018) Hai-Yu Xu et al.   NUCLEIC ACIDS RESEARCH

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

(2018) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Enzymatically synthesized glycogen inhibits colitis through decreasing oxidative stress

(2017) Takakazu Mitani et al.   FREE RADICAL BIOLOGY AND MEDICINE

p53 Expression as a Diagnostic Biomarker in Ulcerative Colitis-Associated Cancer

(2017) Kazuhiro Kobayashi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ulcerative colitis

(2017) Ryan Ungaro et al.   LANCET

TCM-Mesh: The database and analytical system for network pharmacology analysis for TCM preparations

(2017) Run-zhi Zhang et al.   Scientific Reports

Expression and clinical significance of IL-17 and IL-17 receptor in ulcerative colitis

(2016) Heng Zhang et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

IBS and IBD — separate entities or on a spectrum?

(2016) Robin Spiller et al.   Nature Reviews Gastroenterology & Hepatology

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(2016) Yanli Wang et al.   NUCLEIC ACIDS RESEARCH

Oxidative Stress and Carbonyl Lesions in Ulcerative Colitis and Associated Colorectal Cancer

(2016) Zhiqi Wang et al.   Oxidative Medicine and Cellular Longevity

Diarrhea-predominant irritable bowel syndrome: Diagnosis, etiology, and new treatment considerations

(2016) Brian E. Lacy et al.   Journal of the American Association of Nurse Practitioners

BATMAN-TCM: a Bioinformatics Analysis Tool for Molecular mechANism of Traditional Chinese Medicine

(2016) Zhongyang Liu et al.   Scientific Reports

Antioxidant therapy for treatment of inflammatory bowel disease: Does it work?

(2015) Fabiana Andréa Moura et al.   Redox Biology

Receptor for AGEs (RAGE) as Mediator of NF-kB Pathway Activation in Neuroinflammation and Oxidative Stress

(2014) Julio Tobon-Velasco et al.   CNS & Neurological Disorders-Drug Targets

Targeting oxidative stress attenuates trinitrobenzene sulphonic acid induced inflammatory bowel disease like symptoms in rats: Role of quercetin

(2014) Dilip Dodda et al.   INDIAN JOURNAL OF PHARMACOLOGY

Aloe-emodin from rhubarb (Rheum rhabarbarum) inhibits lipopolysaccharide-induced inflammatory responses in RAW264.7 macrophages

(2014) Boyang Hu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Polymorphisms in the Inflammatory Pathway Genes TLR2, TLR4, TLR9, LY96, NFKBIA, NFKB1, TNFA, TNFRSF1A, IL6R, IL10, IL23R, PTPN22, and PPARG Are Associated with Susceptibility of Inflammatory Bowel Disease in a Danish Cohort

(2014) Steffen Bank et al.   PLoS One

TCMSP: a database of systems pharmacology for drug discovery from herbal medicines

(2014) Jinlong Ru et al.   Journal of Cheminformatics

Symptoms of irritable bowel syndrome in patients with inflammatory bowel disease: examining the role of sub-clinical inflammation and the impact on clinical assessment of disease activity

(2013) J. W. Berrill et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Different Profile of Peripheral Antioxidant Enzymes and Lipid Peroxidation in Active and Non-active Inflammatory Bowel Disease Patients

(2013) D. Achitei et al.   DIGESTIVE DISEASES AND SCIENCES

Functional bowel symptoms in quiescent inflammatory bowel diseases: role of epithelial barrier disruption and low-grade inflammation

(2013) M Vivinus-Nébot et al.   GUT

The complexity of NF-κB signaling in inflammation and cancer

(2013) Bastian Hoesel et al.   Molecular Cancer

Calprotectin Is a Useful Tool in Distinguishing Coexisting Irritable Bowel-Like Symptoms from That of Occult Inflammation among Inflammatory Bowel Disease Patients in Remission

(2013) Lars-Petter Jelsness-Jørgensen et al.   Gastroenterology Research and Practice

Review article: associations between immune activation, intestinal permeability and the irritable bowel syndrome

(2012) J. Matricon et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Prevalence of Symptoms Meeting Criteria for Irritable Bowel Syndrome in Inflammatory Bowel Disease: Systematic Review and Meta-Analysis

(2012) Stephen J Halpin et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Risk of Colorectal Cancer in Patients With Ulcerative Colitis: A Meta-analysis of Population-Based Cohort Studies

(2012) Tine Jess et al.   Clinical Gastroenterology and Hepatology

The brain–gut pathway in functional gastrointestinal disorders is bidirectional: a 12-year prospective population-based study

(2012) N A Koloski et al.   GUT

DNA methylation of colon mucosa in ulcerative colitis patients: Correlation with inflammatory status

(2011) Shunsuke Saito et al.   INFLAMMATORY BOWEL DISEASES

TCM Database@Taiwan: The World's Largest Traditional Chinese Medicine Database for Drug Screening In Silico

(2011) Calvin Yu-Chian Chen   PLoS One

TLR-4, IL-1R and TNF-R signaling to NF-κB: variations on a common theme

(2008) L. Verstrepen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES