HIF-1 inhibitor-based one-stone-two-birds strategy for enhanced cancer chemodynamic-immunotherapy

Engineering nanomedicines to inhibit hypoxia-inducible Factor-1 for cancer therapy

(2022) Xiaojuan Zhang et al.   CANCER LETTERS

Heterojunction engineered bioactive chlorella for cascade promoted cancer therapy

(2022) Meitong Ou et al.   JOURNAL OF CONTROLLED RELEASE

A Multimodal Therapeutic Nanoplatform Overcoming Tumor Hypoxia Heterogeneity for Improved Tumor Chemoradiotherapy

(2022) Lanqiong Zhang et al.   ADVANCED FUNCTIONAL MATERIALS

Polypyrrole Nanoenzymes as Tumor Microenvironment Modulators to Reprogram Macrophage and Potentiate Immunotherapy

(2022) Weiwei Zeng et al.   Advanced Science

A smart O2-generating nanocarrier optimizes drug transportation comprehensively for chemotherapy improving

(2021) Xiaojuan Zhang et al.   Acta Pharmaceutica Sinica B

Self-assembled FeS-based cascade bioreactor with enhanced tumor penetration and synergistic treatments to trigger robust cancer immunotherapy

(2021) Hao Ren et al.   Acta Pharmaceutica Sinica B

Catalytically Active CoFe2O4 Nanoflowers for Augmented Sonodynamic and Chemodynamic Combination Therapy with Elicitation of Robust Immune Response

(2021) Shiyan Fu et al.   ACS Nano

Cyclic reactions-mediated self-supply of H2O2 and O2 for cooperative chemodynamic/starvation cancer therapy

(2021) Xiaojuan Zhang et al.   BIOMATERIALS

Symphony of nanomaterials and immunotherapy based on the cancer‒immunity cycle

(2021) Qianqian Li et al.   Acta Pharmaceutica Sinica B

Designing Stimuli-Responsive Upconversion Nanoparticles that Exploit the Tumor Microenvironment

(2020) Muhammad Ovais et al.   ADVANCED MATERIALS

MnO x Nanospikes as Nanoadjuvants and Immunogenic Cell Death Drugs with Enhanced Antitumor Immunity and Antimetastatic Effect

(2020) Binbin Ding et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Curcumol inhibits the expression of programmed cell death-ligand 1 through crosstalk between hypoxia-inducible factor-1α and STAT3 (T705) signaling pathways in hepatic cancer

(2020) Hong Xiang Zuo et al.   JOURNAL OF ETHNOPHARMACOLOGY

Tumor Microenvironment-Responsive Cu2(OH)PO4 Nanocrystals for Selective and Controllable Radiosentization via the X-ray-Triggered Fenton-like Reaction

(2019) Chenyang Zhang et al.   NANO LETTERS

A Multifunctional Cascade Bioreactor Based on Hollow‐Structured Cu 2 MoS 4 for Synergetic Cancer Chemo‐Dynamic Therapy/Starvation Therapy/Phototherapy/Immunotherapy with Remarkably Enhanced Efficacy

(2019) Mengyu Chang et al.   ADVANCED MATERIALS

Tumor Oxygenation and Hypoxia Inducible Factor-1 Functional Inhibition via a Reactive Oxygen Species Responsive Nanoplatform for Enhancing Radiation Therapy and Abscopal Effects

(2018) Lingtong Meng et al.   ACS Nano

Chemodynamic Therapy: Tumour Microenvironment-Mediated Fenton and Fenton-like Reaction

(2018) Zhongmin Tang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Immunotherapy of cancers comes of age

(2017) Hila Yousefi et al.   Expert Review of Clinical Immunology

Tumor-selective catalytic nanomedicine by nanocatalyst delivery

(2017) Minfeng Huo et al.   Nature Communications

A2A adenosine receptor antagonists to weaken the hypoxia-HIF-1α driven immunosuppression and improve immunotherapies of cancer

(2016) Stephen M Hatfield et al.   CURRENT OPINION IN PHARMACOLOGY

Anticancer metal drugs and immunogenic cell death

(2016) Alessio Terenzi et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Hypoxic stress: obstacles and opportunities for innovative immunotherapy of cancer

(2016) S Chouaib et al.   ONCOGENE

Hypoxic control of metastasis

(2016) E. B. Rankin et al.   SCIENCE

Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype

(2015) Haiquan Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation

(2014) Muhammad Zaeem Noman et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Review of iron-free Fenton-like systems for activating H2O2 in advanced oxidation processes

(2014) Alok D. Bokare et al.   JOURNAL OF HAZARDOUS MATERIALS

Tumor endothelium FasL establishes a selective immune barrier promoting tolerance in tumors

(2014) Gregory T Motz et al.   NATURE MEDICINE

Synthesis, self-assembly, and characterization of PEG-coated iron oxide nanoparticles as potential MRI contrast agent

(2010) Chen Yue-Jian et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

The redox state of glutathione regulates the hypoxic induction of HIF-1

(2009) Masamichi Tajima et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Lactic Acid and Acidification Inhibit TNF Secretion and Glycolysis of Human Monocytes

(2009) K. Dietl et al.   JOURNAL OF IMMUNOLOGY