Article
Biotechnology & Applied Microbiology
Hongbo Wang, Kuangqi Yan, Huaran Xing, Jingdi Chen, Rong Lu
Summary: HA microspheres synthesized from waste abalone shells showed high adsorption capacity for Cu2+ in wastewater, with a potential for environmental protection. Thermodynamic analysis indicated the removal process was spontaneous and exothermic.
ENVIRONMENTAL TECHNOLOGY & INNOVATION
(2021)
Article
Biophysics
Meiqi Cheng, Le Hu, Panpan Pan, Qing Liu, Ziyue Zhang, Chunxiao Wang, Man Liu, Jingdi Chen
Summary: In this study, shell-based economical and environmentally friendly magnetic hydroxyapatite microsphere adsorbents (Fe3O4 @SiO2/HAP) were developed for the removal of methyl orange (MO) from simulated wastewater. The adsorbents showed good adsorption properties and recycling performance under acidic conditions, providing a new pathway for the high-value utilization of waste shell resources and the removal of azo dyes.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Article
Engineering, Chemical
Hongbo Wang, Huaran Xing, Kuangqi Yan, Duiwen Han, Jingdi Chen
Summary: Discharging of dyestuff is a significant cause of water pollution. In this study, hydroxyapatite microspheres prepared from oyster shell wastes were used to mimic the removal of Coomassie brilliant blue (CBB) in wastewater. Factors such as solution pH, initial CBB concentration, and temperature were investigated to determine their effects on the adsorption capacity. The results showed that the hydroxyapatite microspheres exhibited strong adsorption capacity for CBB and could be reused effectively.
ADVANCED POWDER TECHNOLOGY
(2022)
Article
Materials Science, Multidisciplinary
Hongbo Wang, Kuangqi Yan, Jingdi Chen
Summary: This study converted marine shell waste into HA microspheres for the removal of dye pollution. The HA microspheres showed high adsorption capacity for CR, reaching up to 495.5626 mg/g. The adsorption process of CR by HA microspheres was found to be spontaneous and exothermic.
Article
Engineering, Multidisciplinary
Zuliantoni Zuliantoni, Wahyono Suprapto, Putu Hadi Setyarini, Femiana Gapsari
Summary: This study synthesized hydroxyapatite from snail shells using the hydrothermal method, and the results showed that the synthetic hydroxyapatite had similar structure and composition to commercial samples. This provides a theoretical basis for the application of snail shell hydroxyapatite and suggests further research directions.
RESULTS IN ENGINEERING
(2022)
Article
Environmental Sciences
A. Prihanto, S. Muryanto, A. Sancho Vaquer, W. W. Schmahl, R. Ismail, J. Jamari, A. P. Bayuseno
Summary: This study demonstrates the use of a low-temperature hydrothermal method to extract calcium sources from green mussel shell wastes and convert them into synthetic nanosized hydroxyapatite. The raw mussel shells were processed to produce a calcium carbonate-rich powder, which was then calcined to obtain a calcium-rich feedstock. Dissolving the calcined powder in aqueous solutions and reacting with phosphoric acid yielded pure nanoscale carbonated HA crystals. This approach of utilizing low-cost mussel shell wastes for large-scale hydroxyapatite nanoparticle production is significant for the industry's development.
ENVIRONMENTAL TECHNOLOGY
(2023)
Article
Biochemistry & Molecular Biology
Shih-Ching Wu, Hsueh-Chuan Hsu, Hsueh-Fang Wang, Shu-Ping Liou, Wen-Fu Ho
Summary: In this study, hydroxyapatite (HA) powder is prepared via the hydrothermal method using eggshell and mulberry leaf extract as raw materials. The results show that the HA prepared using the hydrothermal method exhibits good bioactivity and in vitro biocompatibility, with similar morphology, crystallite size, and composition to natural bone. Therefore, the prepared nano-HA powder has great potential in biomedical applications.
Article
Chemistry, Multidisciplinary
Vignesh Raj Sivaperumal, Rajkumar Mani, Veerababu Polisetti, Kanakaraj Aruchamy, Taehwan Oh
Summary: Calcium phosphate-based ceramic material is a potential candidate for dental restorations and bone replacements, but its limited thermal processing ability and weak mechanical strength have hindered its application in hard tissue engineering. In this study, zirconia was used to reinforce hydroxyapatite, resulting in improved biocompatibility and mechanical stability.
APPLIED SCIENCES-BASEL
(2022)
Article
Engineering, Chemical
Chen-Hsueh Lin, Yu-Hua Xiao, Yan-Ting Lin, Ping-Hsuan Wu, Teng-Hao Chen, Wei-Cheng Li, Li-Hsiang Tseng, Po-Hsin Wang, Ten-Chin Wen
Summary: The use of hydroxyapatite induced by carboxylated chitosan as an active filler for pseudo solid-state supercapacitor can effectively reduce crystalline region, increase amorphous region, decrease internal resistance and heat dissipation, enhance segmental motion and ion migration, making it a novel filler for superior solid-state energy storage devices.
JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS
(2021)
Article
Chemistry, Physical
Yuan-Shun Lo, Chien-Chun Chang, Ping-Chun Lin, Shu-Ping Lin, Chih-Liang Wang
Summary: A structurally tunable hydroxyapatite coating was successfully synthesized on a titanium alloy surface using a hydrothermal method. The treated titanium alloy exhibited rapid growth of hydroxyapatite fibers, forming a porous structure that enhanced bioactivity compared to untreated surfaces. The presence of TiO2 was found to assist in the initial nucleation of hydrothermal hydroxyapatite growth, indicating potential for structurally controlled biomaterials for implants.
APPLIED SURFACE SCIENCE
(2021)
Article
Materials Science, Ceramics
Shahid Hussain, Kazi Sabiruddin
Summary: Hydroxyapatite (HA) powder was successfully synthesized from low-cost Indian clam seashells using a hydrothermal method. The HA obtained from different reaction conditions was mainly non-stoichiometric, with the highest near stoichiometric crystalline HA being produced at 900 degrees C for 2 hours. Increasing reaction temperature led to larger grain sizes of pure HA, while different shapes of grains were observed at varying temperatures.
CERAMICS INTERNATIONAL
(2021)
Article
Materials Science, Coatings & Films
Daihua He, Xuexian Zhang, Ping Liu, Xinkuan Liu, Xiaohong Chen, Fengcang Ma, Wei Li, Ke Zhang, Honglei Zhou
Summary: The hydrothermal treatment improved the properties of electrochemically prepared hydroxyapatite coatings on titanium alloy, healing cracks and increasing density. At 180 degrees C, the coating achieved maximum crystallinity and a bonding strength of about 23 MPa. The coatings obtained through electrochemical method and hydrothermal treatment showed good bioactivity.
SURFACE & COATINGS TECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Vignesh Raj Sivaperumal, Rajkumar Mani, Veerababu Polisetti, Kanakaraj Aruchamy, Taehwan Oh
Summary: In this study, HAp-ZnO nanorod nanocomposites were successfully prepared using a customized hydrothermal reactor and their compatibility with MG-63 osteoblast-like cells was studied. The crystallinity, morphology, presence of chemical elements, and surface area properties of the samples were analyzed using various techniques. Mechanical strength and thermal stability were evaluated using nanoindentation and thermogravimetric/differential scanning calorimeter methods. In vitro biocompatibility studies were conducted with human osteosarcoma cell lines. The results demonstrated improved mechanical strength and thermal stability of the HAp matrix due to the reinforcement of ZnO, and confirmed the biocompatible nature of the biomimetic hydroxyapatite in the composite.
Article
Biochemistry & Molecular Biology
Yu Zhang, Ying-Jie Zhu, Han-Ping Yu
Summary: Ultralong hydroxyapatite (HAP) nanowires have potential biomedical applications due to their similarity to bone composition and excellent properties. However, controlling their formation and the long synthesis time have been challenging. This study introduces an eco-friendly microwave hydrothermal method that uses adenosine 5'-triphosphate (ATP) as a bio-phosphorus source and water as the only solvent for rapid synthesis of ultralong HAP nanowires. The resulting nanowires show high flexibility, self-assemble into bundles, and have excellent bioactivity on chitosan scaffolds.
Article
Chemistry, Physical
Giovanni Garcia Dominguez, Sebastian Diaz De la Torre, Lorena Chavez Gueitron, Erasto Vergara Hernandez, Joan Reyes Miranda, Maribel Quezada Cruz, Aristeo Garrido Hernandez
Summary: Hydroxyapatite nanoparticles with a homogeneous rod morphology were successfully synthesized using the hydrothermal method in this study. The addition of surfactants was found to modify the length/diameter ratio of the HAp rods and promote antibacterial activity. Dermal irritation analysis showed no adverse effects in rabbits during the study.
Article
Engineering, Biomedical
Peng Ding, Qianqian Wei, Ning Tian, Xiaoyue Ding, Ling Wang, Bin Wang, Oseweuba Valentine Okoro, Amin Shavandi, Lei Nie
Summary: This study successfully synthesized sialylated chitosan and tyramine-modified gelatin by introducing sialic acid to chitosan and grafting tyramine to gelatin. The interpenetrating polymer network hydrogel was fabricated by blending the two solutions and crosslinking them with horseradish peroxidase. The obtained hydrogel showed excellent cytocompatibility and potential for biomedical applications.
BIOMEDICAL MATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Lei Nie, Qianqian Wei, Meng Sun, Peng Ding, Ling Wang, Yanfang Sun, Xiaoyue Ding, Oseweuba Valentine Okoro, Guohua Jiang, Amin Shavandi
Summary: One major shortcoming of biopolymeric based wound dressing is the lack of an integrated multi-functional system. This study designed hydrogels with fast gel-forming, porous structure, stable storage modulus, suitable swelling capacity, tissue adhesion, transmission property, self-healing behavior, injectability, inherent antibacterial properties, and biocompatibility. Furthermore, Baicalein could be encapsulated into the hydrogels and its release behavior could be regulated. This study provides new insights into designing multi-functional hydrogels as a wound dressing.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Biochemistry & Molecular Biology
Mehdi Azizi, Amin Shavandi, Masoud Hamidi, Shayan Gholizadeh, Mahnaz Mohammadpour, Mohammad Saeid Salami, Hadi Samadian
Summary: Tissue engineering is an innovative approach that combines engineering, biomaterials, and biomedicine to improve conventional bone defect treatment. This study developed bioengineered electroactive and bioactive mineralized carbon nanofibers as a scaffold for bone tissue engineering. The fabricated scaffold showed osteoactivity, electrical conductivity, and biocompatibility, making it an effective solution for bone tissue engineering.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
(2023)
Article
Biochemistry & Molecular Biology
Parinaz Hobbi, Oseweuba Valentine Okoro, Maryam Hajiabbas, Masoud Hamidi, Lei Nie, Veronique Megalizzi, Paul Musonge, Gianina Dodi, Amin Shavandi
Summary: Apple pomace (AP) from the food industry contains bioactive polyphenolic compounds. This study focuses on the recovery and evaluation of these compounds from different fractions of AP. Subcritical water extraction showed higher total polyphenolic compounds (39.08 mg GAE/g db) compared to ethanol extraction (10.78 mg GAE/g db). HPLC analysis identified phloridzin, chlorogenic acid, and quercetin as the main polyphenolics in AP.
Article
Engineering, Biomedical
Tianqi Liu, Yanfang Sun, Guohua Jiang, Wenjing Zhang, Rui Wang, Lei Nie, Amin Shavandi, Khaydar E. Yunusov, Uladzislau E. Aharodnikau, Sergey O. Solomevich
Summary: Diabetes chronic wound is a serious medical problem in patients with diabetes, which often leads to complications. A porcupine quill-like multilayer microneedle patch was designed to address the issues of insufficient skin adhesion and bacterial infection. The patch contains antibacterial nanoparticles and a hypoglycemic agent, and is combined with a flexible and adhesive back patching for better tissue adhesion and wound healing. The bioinspired multilayer structure of the patch shows satisfactory mechanical and antibacterial properties, making it a potential dressing platform for promoting wound healing.
ACTA BIOMATERIALIA
(2023)
Article
Materials Science, Multidisciplinary
Pejman Ghaffari-Bohlouli, Hooman Golbaten-Mofrad, Najmeh Najmoddin, Vahabodin Goodarzi, Amin Shavandi, Wei-Hsin Chen
Summary: In this study, the electroconductivity, thermal stability, and mechanical properties of synthesized Poly (glycerol-sebacate-itaconic) (PGSIT) were investigated by incorporating polypyrrole (PPy) and clay within the PGSIT matrix. The addition of PPy and clay improved the conductivity, mechanical strength, and thermal stability of the PGSIT matrix. This PGSIT-PPy-clay composite shows potential as an electroconductive bio-elastomer for tissue engineering applications.
Review
Chemistry, Physical
Zahra Ebrahimvand Dibazar, Lei Nie, Mehdi Azizi, Houra Nekounam, Masoud Hamidi, Amin Shavandi, Zhila Izadi, Cedric Delattre
Summary: Bone tissue engineering combines biomaterials, cells, and bioactive agents to provide advanced treatment options. Scaffolds play a central role, and precise design and fabrication of structures that closely resemble bone tissue have shown promising results. The use of nanotechnology and nanomaterials in scaffolds allows for tailored physicochemical properties and improved interactions with cells and surrounding tissues. Polymeric and carbon nanofibers have attracted attention due to their similarity to bone extracellular matrix and high surface-to-volume ratio. Mineralized nanofibers have shown potential in enhancing bone healing in tissue engineering applications.
Article
Multidisciplinary Sciences
Fatemeh Kabirian, Pieter Baatsen, Mario Smet, Amin Shavandi, Petra Mela, Ruth Heying
Summary: Small diameter vascular grafts (SDVGs) often fail due to poor endothelialization, but the incorporation of a nitric oxide (NO) releasing system using S-nitroso-N-acetyl-D-penicillamine (SNAP) loaded in multi-walled carbon nanotubes (MWCNTs) can improve biocompatibility. Coating SDVGs with a 1:1 ratio of polyethylene glycol and SNAP-loaded matrix with MWCNTs-OH significantly enhances endothelial cell (EC) proliferation and migration, while reducing bacterial viability. This newly developed SNAP-loaded MWCNT-OH has great potential for prolonged and controlled NO release, promoting in-situ endothelialization and tissue integration.
SCIENTIFIC REPORTS
(2023)
Article
Pharmacology & Pharmacy
Maria Abedin Zadeh, Raid G. Alany, Leila Satarian, Amin Shavandi, Mohamed Abdullah Almousa, Steve Brocchini, Mouhamad Khoder
Summary: There are limited treatments currently available for retinal diseases such as age-related macular degeneration (AMD). Cell-based therapy holds great promise in treating these degenerative diseases. This study investigates the potential of 3D polymeric scaffolds made up of alginate and bovine serum albumin (BSA) for drug delivery and retinal disease treatment.
Correction
Engineering, Biomedical
Tianqi Liu, Yanfang Sun, Guohua Jiang, Wenjing Zhang, Rui Wang, Lei Nie, Amin Shavandi, Khaydar E. Yunusov, Uladzislau E. Aharodnikau, Sergey O. Solomevich
ACTA BIOMATERIALIA
(2023)
Article
Chemistry, Applied
Camila Gruber Chiaregato, Oigres Daniel Bernardinelli, Amin Shavandi, Edvaldo Sabadini, Denise Freitas Siqueira Petri
Summary: This study systematically investigated the interactions between HPMC cryogels and water molecules in the presence and absence of a surfactant and CaO2 microparticles. Regardless of the DS and MS, most water molecules exhibited transverse relaxation time t2 typical of intermediate water and a small population of tightly bound water. HPMC cryogels with the highest DS showed the slowest swelling rate and the highest contact angle values, providing the optimal conditions for a slow reaction with CaO2. The presence of surfactant favored hydrophobic interactions, resulting in a higher swelling rate and lower contact angle values.
CARBOHYDRATE POLYMERS
(2023)
Article
Engineering, Environmental
Ahmad Allahbakhsh, Zeinab Jarrahi, Gholamali Farzi, Amin Shavandi
Summary: A class of metal-organic nanoparticles-embedded reduced graphene oxide (rGO) nanocomposite aerogels with both solar steam generation behavior and antibacterial properties are developed. By varying the content of Cu-BTC nanoparticles, the surface area, pore texture, and evaporation rate of the nanocomposite aerogels are altered to achieve high energy conversion efficiency and antibacterial properties. The Cu-BTC/rGO aerogel demonstrates an evaporation rate of 1.13 kg/m^2h and an efficiency of 81.8% when the highest content of Cu-BTC nanoparticles is introduced. Furthermore, the Cu-BTC/rGO aerogel shows antibacterial activity against S. aureus and E. coli, making it a potential material for solar steam generation systems for treating wastewater contaminated with pathogenic bacteria.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Engineering, Environmental
Pejman Ghaffari-Bohlouli, Houman Alimoradi, Denise Freitas Siqueira Petri, Saeid Moghassemi, Christiani A. Amorim, Lei Nie, Amin Shavandi
Summary: To effectively alleviate hypoxia and promote proper healing of chronic wounds, the study proposes a new approach using fluorinated chitosan infused with self-generating and preserving oxygen and hydrogen peroxide. By incorporating calcium peroxide-loaded polycaprolactone particles into the fluorinated chitosan matrix, the release kinetics of oxygen and hydrogen peroxide were evaluated. The results show that the incorporation of calcium peroxide into polycaprolactone particles and fluorinated chitosan effectively slows down the release of oxygen and improves cell viability, indicating potential for improving chronic wound healing.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Biophysics
Saeid Moghassemi, Arezoo Dadashzadeh, Hafez Jafari, Pejman Ghaffari-Bohlouli, Amin Shavandi, Christiani A. Amorim
Summary: This study developed a liposomal oxygen-releasing scaffold to address the inadequate oxygen supply in tissue engineering. The results showed that this method can improve cell viability under hypoxic conditions, providing a simple and effective solution for cellular oxygenation.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Review
Chemistry, Multidisciplinary
Lei Nie, Yanfang Sun, Oseweuba Valentine Okoro, Yaling Deng, Guohua Jiang, Amin Shavandi
Summary: Bioinks are used in 3D scaffold fabrication for regenerative medicine, allowing controlled introduction and localization of macromolecules, bioactives, and cells. Crosslinkers, such as click chemistry technology, are employed to prepare bioinks, but some strategies may compromise cytocompatibility. This study explores the potential of click chemistry in bioprinting techniques, identifies major bioinks, and discusses existing challenges and future trends. This review provides an important resource for bioengineers in selecting the preferred click chemistry for specific bioink functionalities.
MATERIALS HORIZONS
(2023)
Article
Engineering, Chemical
Xu Yang, Jieshi Xiao, Jian Huang, Kaixiang Peng
Summary: This study introduces an online convolutional adversarial autoencoder (AAE) model to learn representative industrial process information. By extracting features that reflect diverse information and follow a Gaussian distribution, the model improves the accuracy of fault detection and removes redundant information through a feature selection strategy.
JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS
(2024)
Article
Engineering, Chemical
Shao-Yang Wu, Meng-Tsun Lai, Chung-Hui Hsu, Kevin C. W. Wu, Yesong Gu
Summary: This study investigated the effectiveness of using Fe-based MOF or MIL-100(Fe) in conjunction with a PEDOT-modified Pt electrode for detecting the synthetic azo dye tartrazine. By modifying the electrode with two different methods, favorable lower reductive potentials, competitive sensitivities, and good repeatability and stability were achieved in all MIL-100(Fe)/PEDOT/Pt electrodes.
JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS
(2024)
