Butein Inhibits Cell Growth by Blocking the IL-6/IL-6Rα Interaction in Human Ovarian Cancer and by Regulation of the IL-6/STAT3/FoxO3a Pathway

Prognostic immunologic signatures in epithelial ovarian cancer

(2022) Nicole E. James et al.   ONCOGENE

XPO1 inhibition synergizes with PARP1 inhibition in small cell lung cancer by targeting nuclear transport of FOXO3a

(2021) Jingya Wang et al.   CANCER LETTERS

Insights into Intra-Tumoral Heterogeneity: Transcriptional Profiling of Chemoresistant MPM Cell Subpopulations Reveals Involvement of NFkB and DNA Repair Pathways and Contributes a Prognostic Signature

(2021) Mario Cioce et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Chemical Constituents of Psychotria hainanensis

(2020) Jian Cao et al.   CHEMISTRY OF NATURAL COMPOUNDS

Synthesis and evaluation of butein derivatives for in vitro and in vivo inflammatory response suppression in lymphedema

(2020) Kangsan Roh et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Targeting the IL-6/JAK/STAT3 signalling axis in cancer

(2018) Daniel E. Johnson et al.   Nature Reviews Clinical Oncology

Butein Activates Autophagy Through AMPK/TSC2/ULK1/mTOR Pathway to Inhibit IL-6 Expression in IL-1β Stimulated Human Chondrocytes

(2018) Mohammad Y. Ansari et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Critical role of FOXO3a in carcinogenesis

(2018) Ying Liu et al.   Molecular Cancer

The role of the interleukin (IL)-6/IL-6 receptor axis in cancer

(2018) Mustafa Yassin Taher et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

IL-6 and ovarian cancer: inflammatory cytokines in promotion of metastasis

(2018) Landon Browning et al.   Cancer Management and Research

Butein in health and disease: A comprehensive review

(2017) Ganesan Padmavathi et al.   PHYTOMEDICINE

Rhus verniciflua Stokes (RVS) and butein induce apoptosis of paclitaxel-resistant SKOV-3/PAX ovarian cancer cells through inhibition of AKT phosphorylation

(2016) Hyeong Sim Choi et al.   BMC Complementary and Alternative Medicine

Butein inhibits cell proliferation and induces cell cycle arrest in acute lymphoblastic leukemia via FOXO3a/p27kip1 pathway

(2016) Yan-Lai Tang et al.   Oncotarget

Potential therapeutic implications of IL-6/IL-6R/gp130-targeting agents in breast cancer

(2016) Tae-Hwe Heo et al.   Oncotarget

Butein Shows Cytotoxic Effects and Induces Apoptosis in Human Ovarian Cancer Cells

(2015) Pei-Yu Yang et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Butein, a tetrahydroxychalcone, suppresses pro-inflammatory responses in HaCaT keratinocytes

(2015) Won Yong Seo et al.   BMB Reports

Butein sensitizes HeLa cells to cisplatin through the AKT and ERK/p38 MAPK pathways by targeting FoxO3a

(2015) LIRUI ZHANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Evaluation of leishmanicidal and trypanocidal activities of phenolic compounds fromCalea unifloraLess.

(2015) Tamires C. Lima et al.   NATURAL PRODUCT RESEARCH

Butein suppresses cervical cancer growth through the PI3K/AKT/mTOR pathway

(2015) XUE BAI et al.   ONCOLOGY REPORTS

Potential of butein, a tetrahydroxychalcone to obliterate cancer

(2015) Ganesan Padmavathi et al.   PHYTOMEDICINE

Butein effects in colitis and interleukin-6/signal transducer and activator of transcription 3 expression

(2015) Sehe Dong Lee   WORLD JOURNAL OF GASTROENTEROLOGY

Cisplatin Induces Overactivation of the Dormant Primordial Follicle through PTEN/AKT/FOXO3a Pathway which Leads to Loss of Ovarian Reserve in Mice

(2015) Eun Mi Chang et al.   PLoS One

STAT3 Protein Promotes T-cell Survival and Inhibits Interleukin-2 Production through Up-regulation of Class O Forkhead Transcription Factors

(2011) Hyun-Mee Oh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of neuraminidase activity by polyphenol compounds isolated from the roots of Glycyrrhiza uralensis

(2010) Young Bae Ryu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Bioactive Flavonoids of the Flowers of Butea monosperma

(2009) Ratchanaporn Chokchaisiri et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Phenolic Derivatives from Fruits ofDipteryx lacuniferaDucke and Evaluation of Their Antiradical Activities

(2008) Gerardo Magela V. Júnior et al.   HELVETICA CHIMICA ACTA

Doxorubicin activates FOXO3a to induce the expression of multidrug resistance gene ABCB1 (MDR1) in K562 leukemic cells

(2008) R. C-Y. Hui et al.   MOLECULAR CANCER THERAPEUTICS

Antimicrobial and Antioxidative Activities of Bioactive Constituents from Hydnophytum formicarum Jack.

(2008) Supaluk Prachayasittikul et al.   MOLECULES