Japanese Society of Medical Oncology/Japan Society of Clinical Oncology/Japanese Society of Pediatric Hematology/Oncology-led clinical recommendations on the diagnosis and use of tropomyosin receptor kinase inhibitors in adult and pediatric patients with neurotrophic receptor tyrosine kinase fusion-positive advanced solid tumors

NTRK fusions and Trk proteins: what are they and how to test for them

(2021) Lawrence M. Weiss et al.   HUMAN PATHOLOGY

Larotrectinib in patients with TRK fusion-positive solid tumours: a pooled analysis of three phase 1/2 clinical trials

(2020) David S Hong et al.   LANCET ONCOLOGY

JSCO—ESMO—ASCO—JSMO—TOS: international expert consensus recommendations for tumour-agnostic treatments in patients with solid tumours with microsatellite instability or NTRK fusions

(2020) T. Yoshino et al.   ANNALS OF ONCOLOGY

Antitumor Activity of Larotrectinib in Esophageal Carcinoma with NTRK Gene Amplification

(2020) Dirk Hempel et al.   ONCOLOGIST

Mesenchymal tumors of the gastrointestinal tract with NTRK rearrangements: a clinicopathological, immunophenotypic, and molecular study of eight cases, emphasizing their distinction from gastrointestinal stromal tumor (GIST)

(2020) Mazen A. Atiq et al.   MODERN PATHOLOGY

Spotlight on the treatment of infantile fibrosarcoma in the era of neurotrophic tropomyosin receptor kinase inhibitors: International consensus and remaining controversies

(2020) Daniel Orbach et al.   EUROPEAN JOURNAL OF CANCER

Feasibility and utility of a panel testing for 114 cancer-associated genes in a clinical setting: A hospital-based study

(2019) Kuniko Sunami et al.   CANCER SCIENCE

Testing algorithm for identification of patients with TRK fusion cancer

(2019) Frédérique Penault-Llorca et al.   JOURNAL OF CLINICAL PATHOLOGY

Detection of Tumor NTRK Gene Fusions to Identify Patients Who May Benefit from TRK Inhibitor Therapy

(2019) Susan J. Hsiao et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Detection of NTRK Fusions: Merits and Limitations of Current Diagnostic Platforms

(2019) James P. Solomon et al.   CANCER RESEARCH

NTRK fusion detection across multiple assays and 33,997 cases: diagnostic implications and pitfalls

(2019) James P. Solomon et al.   MODERN PATHOLOGY

Identifying patients with NTRK fusion cancer

(2019) J P Solomon et al.   ANNALS OF ONCOLOGY

PPM11 TUMOUR-SPECIFIC RANDOMIZED CONTROLLED TRIALS IN RARE ONCOGENE-DRIVEN CANCERS: ASKING FOR THE IMPOSSIBLE?

(2019) G. Lozano-Ortega et al.   VALUE IN HEALTH

Alterations in ALK/ROS1/NTRK/MET drive a group of infantile hemispheric gliomas

(2019) Ana S. Guerreiro Stucklin et al.   Nature Communications

Entrectinib in patients with advanced or metastatic NTRK fusion-positive solid tumours: integrated analysis of three phase 1–2 trials

(2019) Robert C Doebele et al.   LANCET ONCOLOGY

Pan-Trk Immunohistochemistry Identifies NTRK Rearrangements in Pediatric Mesenchymal Tumors

(2018) Erin R. Rudzinski et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Evaluation of pan-TRK immunohistochemistry in infantile fibrosarcoma, lipofibromatosis-like neural tumour and histological mimics

(2018) Yin P Hung et al.   HISTOPATHOLOGY

Comparison of molecular testing modalities for detection of ROS1 rearrangements in a cohort of positive patient samples

(2018) Kurtis D. Davies et al.   Journal of Thoracic Oncology

Efficacy of Larotrectinib in TRK Fusion–Positive Cancers in Adults and Children

(2018) Alexander Drilon et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Use of Neoadjuvant Larotrectinib in the Management of Children With Locally Advanced TRK Fusion Sarcomas

(2018) Steven G. DuBois et al.   CANCER

Molecular characterization of cancers with NTRK gene fusions

(2018) Zoran Gatalica et al.   MODERN PATHOLOGY

Repotrectinib (TPX-0005) Is a Next-Generation ROS1/TRK/ALK Inhibitor That Potently Inhibits ROS1/TRK/ALK Solvent- Front Mutations

(2018) Alexander Drilon et al.   Cancer Discovery

TRK Fusion Cancers in Children: A Clinical Review and Recommendations for Screening

(2018) Catherine M. Albert et al.   JOURNAL OF CLINICAL ONCOLOGY

NTRK fusion-positive cancers and TRK inhibitor therapy

(2018) Emiliano Cocco et al.   Nature Reviews Clinical Oncology

ETV6 -NTRK3 in congenital mesoblastic nephroma: A report of the SIOP/GPOH nephroblastoma study

(2017) Christian Vokuhl et al.   PEDIATRIC BLOOD & CANCER

A Next-Generation TRK Kinase Inhibitor Overcomes Acquired Resistance to Prior TRK Kinase Inhibition in Patients with TRK Fusion–Positive Solid Tumors

(2017) Alexander Drilon et al.   Cancer Discovery

Detecting Gene Rearrangements in Patient Populations Through a 2-Step Diagnostic Test Comprised of Rapid IHC Enrichment Followed by Sensitive Next-Generation Sequencing

(2017) Danielle A. Murphy et al.   APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY

Mammary Analogue Secretory Carcinoma of Salivary Glands

(2016) Alena Skálová et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Conservative strategy in infantile fibrosarcoma is possible: The European paediatric Soft tissue sarcoma Study Group experience

(2016) Daniel Orbach et al.   EUROPEAN JOURNAL OF CANCER

Transcriptome sequencing identifiesETV6-NTRK3as a gene fusion involved in GIST

(2016) Monica Brenca et al.   JOURNAL OF PATHOLOGY

Secretory Breast Carcinoma

(2015) Marie Del Castillo et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY

Acquired Resistance to the TRK Inhibitor Entrectinib in Colorectal Cancer

(2015) M. Russo et al.   Cancer Discovery

The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma

(2014) Gang Wu et al.   NATURE GENETICS

TRKing Down an Old Oncogene in a New Era of Targeted Therapy

(2014) Aria Vaishnavi et al.   Cancer Discovery

Utility of mammaglobin immunohistochemistry as a proxy marker for the ETV6-NTRK3 translocation in the diagnosis of salivary mammary analogue secretory carcinoma

(2013) Justin A. Bishop et al.   HUMAN PATHOLOGY

Mammary analogue secretory carcinoma: Update on a new diagnosis of salivary gland malignancy

(2013) Roshan Sethi et al.   LARYNGOSCOPE

Mammary Analogue Secretory Carcinoma of Salivary Glands, Containing the ETV6-NTRK3 Fusion Gene: A Hitherto Undescribed Salivary Gland Tumor Entity

(2010) Alena Skálová et al.   AMERICAN JOURNAL OF SURGICAL PATHOLOGY