The clinical application of polygenic risk scores: A points to consider statement of the American College of Medical Genetics and Genomics (ACMG)

Laboratory perspectives in the development of polygenic risk scores for disease: A points to consider statement of the American College of Medical Genetics and Genomics (ACMG)

(2023) Honey V. Reddi et al.   GENETICS IN MEDICINE

Calculating Polygenic Risk Scores (PRS) in UK Biobank: A Practical Guide for Epidemiologists

(2022) Jennifer A. Collister et al.   Frontiers in Genetics

Including diverse and admixed populations in genetic epidemiology research

(2022) Amke Caliebe et al.   GENETIC EPIDEMIOLOGY

Addressing the routine failure to clinically identify monogenic cases of common disease

(2022) Michael F. Murray et al.   Genome Medicine

Race and Genetic Ancestry in Medicine — A Time for Reckoning with Racism

(2021) Luisa N. Borrell et al.   NEW ENGLAND JOURNAL OF MEDICINE

Improving reporting standards for polygenic scores in risk prediction studies

(2021) Hannah Wand et al.   NATURE

The Polygenic Score Catalog as an open database for reproducibility and systematic evaluation

(2021) Samuel A. Lambert et al.   NATURE GENETICS

Concordance of a High Polygenic Score Among Relatives

(2021) Nicholas J. Reid et al.   Circulation-Genomic and Precision Medicine

Direct-to-consumer prenatal testing for multigenic or polygenic disorders: a position statement of the American College of Medical Genetics and Genomics (ACMG)

(2021)   GENETICS IN MEDICINE

Problems with Using Polygenic Scores to Select Embryos

(2021) Patrick Turley et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genetic prediction of complex traits with polygenic scores: a statistical review

(2021) Ying Ma et al.   TRENDS IN GENETICS

Predictive Accuracy of a Polygenic Risk Score Compared With a Clinical Risk Score for Incident Coronary Heart Disease

(2020) Jonathan D. Mosley et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Molecular Genetic Risk for Psychosis Is Associated With Psychosis Risk Symptoms in a Population-Based UK Cohort: Findings From Generation Scotland

(2020) Anna R Docherty et al.   SCHIZOPHRENIA BULLETIN

Dimensionality reduction reveals fine-scale structure in the Japanese population with consequences for polygenic risk prediction

(2020) Saori Sakaue et al.   Nature Communications

Tutorial: a guide to performing polygenic risk score analyses

(2020) Shing Wan Choi et al.   Nature Protocols

Polygenic background modifies penetrance of monogenic variants for tier 1 genomic conditions

(2020) Akl C. Fahed et al.   Nature Communications

The illusion of polygenic disease risk prediction

(2019) Nicholas J. Wald et al.   GENETICS IN MEDICINE

Clinical use of current polygenic risk scores may exacerbate health disparities

(2019) Alicia R. Martin et al.   NATURE GENETICS

Towards clinical utility of polygenic risk scores

(2019) Samuel A Lambert et al.   HUMAN MOLECULAR GENETICS

Genome-wide Association Studies in Ancestrally Diverse Populations: Opportunities, Methods, Pitfalls, and Recommendations

(2019) Roseann E. Peterson et al.   CELL

The personal and clinical utility of polygenic risk scores

(2018) Ali Torkamani et al.   NATURE REVIEWS GENETICS

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

(2018) Nasim Mavaddat et al.   AMERICAN JOURNAL OF HUMAN GENETICS

The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019

(2018) Annalisa Buniello et al.   NUCLEIC ACIDS RESEARCH

Developing and evaluating polygenic risk prediction models for stratified disease prevention

(2016) Nilanjan Chatterjee et al.   NATURE REVIEWS GENETICS

Dissecting the genetics of complex traits using summary association statistics

(2016) Bogdan Pasaniuc et al.   NATURE REVIEWS GENETICS

Genetic Risk, Adherence to a Healthy Lifestyle, and Coronary Disease

(2016) Amit V. Khera et al.   NEW ENGLAND JOURNAL OF MEDICINE

Projecting the performance of risk prediction based on polygenic analyses of genome-wide association studies

(2013) Nilanjan Chatterjee et al.   NATURE GENETICS

Power and Predictive Accuracy of Polygenic Risk Scores

(2013) Frank Dudbridge   PLoS Genetics

Five Years of GWAS Discovery

(2012) Peter M. Visscher et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

(2009) Shaun M. Purcell et al.   NATURE