The biogenesis, biological functions and modification of Circular RNAs

ADARs act as potent regulators of circular transcriptome in cancer

(2022) Haoqing Shen et al.   Nature Communications

Reduction of A-to-I RNA editing in the failing human heart regulates formation of circular RNAs

(2022) Karoline E. Kokot et al.   BASIC RESEARCH IN CARDIOLOGY

Circular RNA and Diabetes: Epigenetic Regulator with Diagnostic role.

(2020) Kazem Abbaszadeh-Goudarzi et al.   CURRENT MOLECULAR MEDICINE

Molecular Mechanisms Driving mRNA Degradation by m6A Modification

(2020) Yujin Lee et al.   TRENDS IN GENETICS

IL-13 secreted by ILC2s promotes the self-renewal of intestinal stem cells through circular RNA circPan3

(2019) Pingping Zhu et al.   NATURE IMMUNOLOGY

Endoribonucleolytic Cleavage of m6A-Containing RNAs by RNase P/MRP Complex

(2019) Ok Hyun Park et al.   MOLECULAR CELL

FNDC3B circular RNA promotes the migration and invasion of gastric cancer cells via the regulation of E‐cadherin and CD44 expression

(2019) Yuling Hong et al.   JOURNAL OF CELLULAR PHYSIOLOGY

CircACC1 Regulates Assembly and Activation of AMPK Complex under Metabolic Stress

(2019) Qidong Li et al.   Cell Metabolism

The RNA-binding protein RBM3 promotes cell proliferation in hepatocellular carcinoma by regulating circular RNA SCD-circRNA 2 production

(2019) Wei Dong et al.   EBioMedicine

CircMYBL2, a circRNA from MYBL2, Regulates FLT3 Translation by Recruiting PTBP1 to Promote FLT3-ITD AML Progression

(2019) Yu-Meng Sun et al.   BLOOD

Circular RNA circFNDC3B protects renal carcinoma by miR‐99a downregulation

(2019) Tao Chen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Sam68 binds Alu-rich introns in SMN and promotes pre-mRNA circularization

(2019) Vittoria Pagliarini et al.   NUCLEIC ACIDS RESEARCH

N6-methyladenosine modification of circNSUN2 facilitates cytoplasmic export and stabilizes HMGA2 to promote colorectal liver metastasis

(2019) Ri-Xin Chen et al.   Nature Communications

The RNA-Binding Protein RBM3 Promotes Neural Stem Cell (NSC) Proliferation Under Hypoxia

(2019) Jingyi Yan et al.   Frontiers in Cell and Developmental Biology

Biosynthetic CircRNA_001160 induced by PTBP1 regulates the permeability of BTB via the CircRNA_001160/miR-195-5p/ETV1 axis

(2019) Hua Li et al.   Cell Death & Disease

Analysis of human ES cell differentiation establishes that the dominant isoforms of the lncRNAs RMST and FIRRE are circular

(2018) Osagie G. Izuogu et al.   BMC GENOMICS

Twist1 regulates Vimentin through Cul2 circular RNA to promote EMT in hepatocellular carcinoma

(2018) Jing Meng et al.   CANCER RESEARCH

A Network of Noncoding Regulatory RNAs Acts in the Mammalian Brain

(2018) Benjamin Kleaveland et al.   CELL

Circular RNA Atp9b, a competing endogenous RNA, regulates the progression of osteoarthritis by targeting miR-138-5p

(2018) Zhi-bin Zhou et al.   GENE

A Circular RNA Protects Dormant Hematopoietic Stem Cells from DNA Sensor cGAS-Mediated Exhaustion

(2018) Pengyan Xia et al.   IMMUNITY

Circular RNA cSMARCA5 inhibits growth and metastasis in hepatocellular carcinoma

(2018) Jian Yu et al.   JOURNAL OF HEPATOLOGY

A novel protein encoded by the circular form of the SHPRH gene suppresses glioma tumorigenesis

(2018) Maolei Zhang et al.   ONCOGENE

CircRNA microarray profiling identifies a novel circulating biomarker for detection of gastric cancer

(2018) Weiwei Tang et al.   Molecular Cancer

Circular RNA in cardiovascular disease

(2018) M-Ashraf Altesha et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Invasion-related circular RNA circFNDC3B inhibits bladder cancer progression through the miR-1178-3p/G3BP2/SRC/FAK axis

(2018) Hongwei Liu et al.   Molecular Cancer

Circular RNA circNOL10 Inhibits Lung Cancer Development by Promoting SCLM1-Mediated Transcriptional Regulation of the Humanin Polypeptide Family

(2018) Aruo Nan et al.   Advanced Science

Translation of CircRNAs

(2017) Nagarjuna Reddy Pamudurti et al.   MOLECULAR CELL

Circ-ZNF609 Is a Circular RNA that Can Be Translated and Functions in Myogenesis

(2017) Ivano Legnini et al.   MOLECULAR CELL

Coordinated circRNA Biogenesis and Function with NF90/NF110 in Viral Infection

(2017) Xiang Li et al.   MOLECULAR CELL

The Circular RNA Interacts with STAT3, Increasing Its Nuclear Translocation and Wound Repair by Modulating Dnmt3a and miR-17 Function

(2017) Zhen-Guo Yang et al.   MOLECULAR THERAPY

DHX9 suppresses RNA processing defects originating from the Alu invasion of the human genome

(2017) Tuğçe Aktaş et al.   NATURE

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing

(2017) Teng Fei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circular RNAs are abundantly expressed and upregulated during human epidermal stem cell differentiation

(2017) Lasse Sommer Kristensen et al.   RNA Biology

Identification of HuR target circular RNAs uncovers suppression of PABPN1 translation by CircPABPN1

(2017) Kotb Abdelmohsen et al.   RNA Biology

The circular RNA circBIRC6 participates in the molecular circuitry controlling human pluripotency

(2017) Chun-Ying Yu et al.   Nature Communications

FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons

(2017) Lorenzo Errichelli et al.   Nature Communications

Induction of tumor apoptosis through a circular RNA enhancing Foxo3 activity

(2016) William W Du et al.   CELL DEATH AND DIFFERENTIATION

Diverse alternative back-splicing and alternative splicing landscape of circular RNAs

(2016) Xiao-Ou Zhang et al.   GENOME RESEARCH

The biogenesis and emerging roles of circular RNAs

(2016) Ling-Ling Chen   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Foxo3 circular RNA retards cell cycle progression via forming ternary complexes with p21 and CDK2

(2016) William W. Du et al.   NUCLEIC ACIDS RESEARCH

Increased complexity of circRNA expression during species evolution

(2016) Rui Dong et al.   RNA Biology

Full-length sequence assembly reveals circular RNAs with diverse non-GT/AG splicing signals in rice

(2016) Chu-Yu Ye et al.   RNA Biology

The Biogenesis of Nascent Circular RNAs

(2016) Yang Zhang et al.   Cell Reports

5′ UTR m6A Promotes Cap-Independent Translation

(2015) Kate D. Meyer et al.   CELL

The RNA Binding Protein Quaking Regulates Formation of circRNAs

(2015) Simon J. Conn et al.   CELL

Combinatorial control ofDrosophilacircular RNA expression by intronic repeats, hnRNPs, and SR proteins

(2015) Marianne C. Kramer et al.   GENES & DEVELOPMENT

Exon Skipping Is Correlated with Exon Circularization

(2015) Steven Kelly et al.   JOURNAL OF MOLECULAR BIOLOGY

Circular RNAs in the Mammalian Brain Are Highly Abundant, Conserved, and Dynamically Expressed

(2015) Agnieszka Rybak-Wolf et al.   MOLECULAR CELL

Dynamic m6A mRNA methylation directs translational control of heat shock response

(2015) Jun Zhou et al.   NATURE

Neural circular RNAs are derived from synaptic genes and regulated by development and plasticity

(2015) Xintian You et al.   NATURE NEUROSCIENCE

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The emerging landscape of circular RNA ciRS-7 in cancer (Review)

(2015) LI PENG et al.   ONCOLOGY REPORTS

Exon-intron circular RNAs regulate transcription in the nucleus

(2015) Zhaoyong Li et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Circular RNA ITCH has inhibitory effect on ESCC by suppressing the Wnt/β-catenin pathway

(2015) Fang Li et al.   Oncotarget

Rolling Circle Translation of Circular RNA in Living Human Cells

(2015) Naoko Abe et al.   Scientific Reports

Analysis of Intron Sequences Reveals Hallmarks of Circular RNA Biogenesis in Animals

(2015) Andranik Ivanov et al.   Cell Reports

Complementary Sequence-Mediated Exon Circularization

(2014) Xiao-Ou Zhang et al.   CELL

Short intronic repeat sequences facilitate circular RNA production

(2014) Dongming Liang et al.   GENES & DEVELOPMENT

circRNA Biogenesis Competes with Pre-mRNA Splicing

(2014) Reut Ashwal-Fluss et al.   MOLECULAR CELL

Coupling mRNA processing with transcription in time and space

(2014) David L. Bentley   NATURE REVIEWS GENETICS

Genome-wide Analysis of Drosophila Circular RNAs Reveals Their Structural and Sequence Properties and Age-Dependent Neural Accumulation

(2014) Jakub O. Westholm et al.   Cell Reports

Rolling Circle Amplification in a Prokaryotic Translation System Using Small Circular RNA

(2013) Naoko Abe et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Circular Intronic Long Noncoding RNAs

(2013) Yang Zhang et al.   MOLECULAR CELL

Natural RNA circles function as efficient microRNA sponges

(2013) Thomas B. Hansen et al.   NATURE

Circular RNAs are a large class of animal RNAs with regulatory potency

(2013) Sebastian Memczak et al.   NATURE

Quaking and PTB control overlapping splicing regulatory networks during muscle cell differentiation

(2013) M. P. Hall et al.   RNA

Cell-Type Specific Features of Circular RNA Expression

(2013) Julia Salzman et al.   PLoS Genetics

Circular RNA (circRNA) in Alzheimer's disease (AD)

(2013) Walter J. Lukiw   Frontiers in Genetics

Circular RNAs are abundant, conserved, and associated with ALU repeats

(2012) W. R. Jeck et al.   RNA

Human RNA Polymerase II-Association Factor 1 (hPaf1/PD2) Regulates Histone Methylation and Chromatin Remodeling in Pancreatic Cancer

(2011) Parama Dey et al.   PLoS One

The Human RNA Polymerase II-Associated Factor 1 (hPaf1): A New Regulator of Cell-Cycle Progression

(2009) Nicolas Moniaux et al.   PLoS One