Galangin alleviated myocardial ischemia-reperfusion injury by enhancing autophagic flux and inhibiting inflammation

USP5 attenuates NLRP3 inflammasome activation by promoting autophagic degradation of NLRP3

(2021) Baoshan Cai et al.   Autophagy

Galangin attenuates diabetic cardiomyopathy through modulating oxidative stress, inflammation and apoptosis in rats

(2021) Mohammad H. Abukhalil et al.   BIOMEDICINE & PHARMACOTHERAPY

GSDMD-Mediated Cardiomyocyte Pyroptosis Promotes Myocardial I/R Injury

(2021) Huairui Shi et al.   CIRCULATION RESEARCH

Platelet‐Like Fusogenic Liposome‐Mediated Targeting Delivery of miR‐21 Improves Myocardial Remodeling by Reprogramming Macrophages Post Myocardial Ischemia‐Reperfusion Injury

(2021) Haipeng Tan et al.   Advanced Science

The natural flavonoid galangin ameliorates dextran sulphate sodium–induced ulcerative colitis in mice: Effect on Toll‐like receptor 4, inflammation and oxidative stress

(2020) Samar H. Gerges et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Galangin Protects against Symptoms of Dextran Sodium Sulfate-Induced Acute Colitis by Activating Autophagy and Modulating the Gut Microbiota

(2020) Hongzhuan Xuan et al.   Nutrients

Downregulation of LAPTM4B Contributes to the Impairment of the Autophagic Flux via Unopposed Activation of mTORC1 Signaling During Myocardial Ischemia/Reperfusion Injury

(2020) Shanshan Gu et al.   CIRCULATION RESEARCH

Galangin Improved Non-Alcoholic Fatty Liver Disease in Mice by Promoting Autophagy

(2020) Xinxu Zhang et al.   Drug Design Development and Therapy

Galangin attenuated cerebral ischemia-reperfusion injury by inhibition of ferroptosis through activating the SLC7A11/GPX4 axis in gerbils

(2020) Xue Guan et al.   LIFE SCIENCES

Galangin Attenuates Isoproterenol-Induced Inflammation and Fibrosis in the Cardiac Tissue of Albino Wistar Rats

(2020) Radhiga Thangaiyan et al.   Frontiers in Pharmacology

Galangin ameliorates cardiac remodeling via the MEK1/2-ERK1/2 and PI3K-AKT pathways

(2019) Hui-Bo Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The macrophage-specific V-ATPase subunit ATP6V0D2 restricts inflammasome activation and bacterial infection by facilitating autophagosome-lysosome fusion

(2019) Yu Xia et al.   Autophagy

The Role of Autophagy in the Heart

(2018) Sebastiano Sciarretta et al.   Annual Review of Physiology

Mammalian target of rapamycin inhibition attenuates myocardial ischaemia-reperfusion injury in hypertrophic heart

(2018) Lei-Lei Ma et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Galangin ameliorates cisplatin-induced nephrotoxicity by attenuating oxidative stress, inflammation and cell death in mice through inhibition of ERK and NF-kappaB signaling

(2017) Yu-Ching Huang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Mff‐Dependent Mitochondrial Fission Contributes to the Pathogenesis of Cardiac Microvasculature Ischemia/Reperfusion Injury via Induction of mROS‐Mediated Cardiolipin Oxidation and HK2/VDAC1 Disassociation‐Involved mPTP Opening

(2017) Hao Zhou et al.   Journal of the American Heart Association

A Simplified, Langendorff-Free Method for Concomitant Isolation of Viable Cardiac Myocytes and Nonmyocytes From the Adult Mouse HeartNovelty and Significance

(2016) Matthew Ackers-Johnson et al.   CIRCULATION RESEARCH

Impaired macrophage autophagy increases the immune response in obese mice by promoting proinflammatory macrophage polarization

(2015) Kun Liu et al.   Autophagy

The role of the autophagy in myocardial ischemia/reperfusion injury

(2015) Sai Ma et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cardiac Oxidative Stress and Inflammatory Cytokines Response after Myocardial Infarction

(2015) Margherita Neri et al.   Current Vascular Pharmacology

Evolving Therapies for Myocardial Ischemia/Reperfusion Injury

(2015) Borja Ibáñez et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Activation of the PI3K-Akt-mTOR signaling pathway promotes necrotic cell death via suppression of autophagy

(2014) You-Tong Wu et al.   Autophagy

Autophagy and human diseases

(2013) Peidu Jiang et al.   CELL RESEARCH

Galangin, a flavonol derived from Rhizoma Alpiniae Officinarum, inhibits acetylcholinesterase activity in vitro

(2010) Ava J.Y. Guo et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Beneficial Effects of Mammalian Target of Rapamycin Inhibition on Left Ventricular Remodeling After Myocardial Infarction

(2009) Sebastian J. Buss et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY