4.3 Review

The changing face of cardiogenic shock: definitions, epidemiology, and severity assessment

Journal

CURRENT OPINION IN CRITICAL CARE
Volume 29, Issue 4, Pages 363-370

Publisher

LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/MCC.0000000000001065

Keywords

assessment; cardiogenic shock; classification; epidemiology; severity

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This review discusses recent advances in the definitions, epidemiology, and severity assessment of cardiogenic shock. More granular assessment of shock severity has the potential to improve outcomes by allowing research to differentiate patient groups with different responses to therapies.
Purpose of reviewCardiogenic shock (CS) has been recognized for >50 years, most commonly in the setting of myocardial infarction. This review covers recent advances in the definitions, epidemiology and severity assessment of cardiogenic shock.Recent findingsIn this review, the authors discuss the evolving definitions of cardiogenic shock, detailing the early approaches as well as more contemporary ideas. The epidemiology of CS is reviewed and then granular detail on the assessment of shock severity is provided including the role of lactate measurement and invasive hemodynamic assessment. The development of the Society for Cardiac Angiography and Intervention (SCAI) consensus statement on Classification of Cardiogenic Shock is reviewed by the principal authors. The revised SCAI Shock document is reviewed as well and the future directions for assessment of shock along with clinical applications are reviewed.Cardiogenic shock mortality has not changed in a significant way in many years. Recent advances such as more granular assessment of shock severity have the potential to improve outcomes by allowing research to separate the patient groups which may respond differently to various therapies.

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