Are Charge-State Distributions a Reliable Tool Describing Molecular Ensembles of Intrinsically Disordered Proteins by Native MS?

Opposite Structural Effects of Epigallocatechin-3-gallate and Dopamine Binding to α-Synuclein

(2016) Albert Konijnenberg et al.   ANALYTICAL CHEMISTRY

Unfolding and Folding of the Three-Helix Bundle Protein KIX in the Absence of Solvent

(2016) Moritz Schennach et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Dynamic structural flexibility of α-synuclein

(2016) Danielle E. Mor et al.   NEUROBIOLOGY OF DISEASE

Conformational dynamics of α-synuclein: insights from mass spectrometry

(2015) Ashley S. Phillips et al.   ANALYST

Small-angle neutron scattering reveals the assembly of alpha-synuclein in lipid membranes

(2015) Divina Anunciado et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Remote His50 Acts as a Coordination Switch in the High-Affinity N-Terminal Centered Copper(II) Site of α-Synuclein

(2015) Riccardo De Ricco et al.   INORGANIC CHEMISTRY

Ensemble Methods Enable a New Definition for the Solution to Gas-Phase Transfer of Intrinsically Disordered Proteins

(2015) Antoni J. Borysik et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

How Closely Related Are Conformations of Protein Ions Sampled by IM-MS to Native Solution Structures?

(2015) Shu-Hua Chen et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Conformational effects in protein electrospray-ionization mass spectrometry

(2015) Jinyu Li et al.   MASS SPECTROMETRY REVIEWS

Alpha-synuclein oligomers and fibrils originate in two distinct conformer pools: a small angle X-ray scattering and ensemble optimisation modelling study

(2015) Cyril C. Curtain et al.   Molecular BioSystems

Relating gas phase to solution conformations: Lessons from disordered proteins

(2015) Rebecca Beveridge et al.   PROTEOMICS

Structure of full-length p53 tumor suppressor probed by chemical cross-linking and mass spectrometry

(2015) Christian Arlt et al.   PROTEOMICS

Introducing Protein Intrinsic Disorder

(2014) Johnny Habchi et al.   CHEMICAL REVIEWS

The conformational response to Zn(II) and Ni(II) binding of Sporosarcina pasteurii UreG, an intrinsically disordered GTPase

(2014) Annalisa D’Urzo et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Metal-Induced Conformational Changes of Human Metallothionein-2A: A Combined Theoretical and Experimental Study of Metal-Free and Partially Metalated Intermediates

(2014) Shu-Hua Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Insights into the Mechanism of Protein Electrospray Ionization From Salt Adduction Measurements

(2014) Xuanfeng Yue et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

What Protein Charging (and Supercharging) Reveal about the Mechanism of Electrospray Ionization

(2014) Rachel R. Ogorzalek Loo et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Molecular Basis for Structural Heterogeneity of an Intrinsically Disordered Protein Bound to a Partner by Combined ESI-IM-MS and Modeling

(2014) Annalisa D’Urzo et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Cooperative Unfolding of Compact Conformations of the Intrinsically Disordered Protein Osteopontin

(2013) Dennis Kurzbach et al.   BIOCHEMISTRY

Under-folded proteins: Conformational ensembles and their roles in protein folding, function, and pathogenesis

(2013) Vladimir N. Uversky   BIOPOLYMERS

Role of Prion Disease-Linked Mutations in the Intrinsically Disordered N-Terminal Domain of the Prion Protein

(2013) Xiaojing Cong et al.   Journal of Chemical Theory and Computation

Mass spectrometry-based methods to study protein architecture and dynamics

(2013) Igor A. Kaltashov et al.   PROTEIN SCIENCE

Twenty Years of Gas Phase Structural Biology

(2013) Julien Marcoux et al.   STRUCTURE

Mass spectrometry methods for intrinsically disordered proteins

(2012) Rebecca Beveridge et al.   ANALYST

Intrinsically Disordered p53 and Its Complexes Populate Compact Conformations in the Gas Phase

(2012) Kevin Pagel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Intrinsic disorder in proteins: a challenge for (un)structural biology met by ion mobility–mass spectrometry

(2012) Ewa Jurneczko et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Native ion mobility-mass spectrometry and related methods in structural biology

(2012) A. Konijnenberg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

A Computational Model for Protein Ionization by Electrospray Based on Gas-Phase Basicity

(2012) Roberto Marchese et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Do Charge State Signatures Guarantee Protein Conformations?

(2012) Zoe Hall et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Structural Disorder in Eukaryotes

(2012) Rita Pancsa et al.   PLoS One

Intrinsically disordered proteins: a 10-year recap

(2012) Peter Tompa   TRENDS IN BIOCHEMICAL SCIENCES

Intramolecular interactions stabilizing compact conformations of the intrinsically disordered kinase-inhibitor domain of Sic1: a molecular dynamics investigation

(2012) Matteo Lambrughi et al.   Frontiers in Physiology

Charge-Surface Correlation in Electrospray Ionization of Folded and Unfolded Proteins

(2011) Lorenzo Testa et al.   ANALYTICAL CHEMISTRY

The Metastasis-Associated Extracellular Matrix Protein Osteopontin Forms Transient Structure in Ligand Interaction Sites

(2011) Gerald Platzer et al.   BIOCHEMISTRY

Compaction Properties of an Intrinsically Disordered Protein: Sic1 and Its Kinase-Inhibitor Domain

(2011) Stefania Brocca et al.   BIOPHYSICAL JOURNAL

Explaining the Structural Plasticity of α-Synuclein

(2011) Orly Ullman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Insights in the (un)structural organization of Bacillus pasteurii UreG, an intrinsically disordered GTPase enzyme

(2011) Barbara Zambelli et al.   Molecular BioSystems

The N0-binding region of the vesicular stomatitis virus phosphoprotein is globally disordered but contains transient α-helices

(2011) Cédric Leyrat et al.   PROTEIN SCIENCE

Estimating the affinity of protein–ligand complex from changes to the charge-state distribution of a protein in electrospray ionization mass spectrometry

(2010) Elizabeth A. Blackburn et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Conformational Analysis of the Partially Disordered Measles Virus NTAIL-XD Complex by SDSL EPR Spectroscopy

(2010) Aleh Kavalenka et al.   BIOPHYSICAL JOURNAL

Electrospray ionization-mass spectrometry conformational analysis of isolated domains of an intrinsically disordered protein

(2010) Lorenzo Testa et al.   Biotechnology Journal

Intein-mediated Cyclization of Bacterial Acyl Carrier Protein Stabilizes Its Folded Conformation but Does Not Abolish Function

(2010) Gerrit Volkmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Solution structure of the C-terminal X domain of the measles virus phosphoprotein and interaction with the intrinsically disordered C-terminal domain of the nucleoprotein

(2010) Stéphane Gely et al.   JOURNAL OF MOLECULAR RECOGNITION

Proteins, Lipids, and Water in the Gas Phase

(2010) David van der Spoel et al.   MACROMOLECULAR BIOSCIENCE

Defining Structural Domains of an Intrinsically Disordered Protein: Sic1, the Cyclin-Dependent Kinase Inhibitor of Saccharomyces cerevisiae

(2010) Stefania Brocca et al.   MOLECULAR BIOTECHNOLOGY

Compact conformations of α-synuclein induced by alcohols and copper

(2010) Antonino Natalello et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

On the Zwitterionic Nature of Gas-Phase Peptides and Protein Ions

(2010) Roberto Marchese et al.   PLoS Computational Biology

19F NMR Studies of α-Synuclein Conformation and Fibrillation

(2009) Conggang Li et al.   BIOCHEMISTRY

Unfoldomics of human diseases: linking protein intrinsic disorder with diseases

(2009) Vladimir N Uversky et al.   BMC GENOMICS

Predicting intrinsic disorder in proteins: an overview

(2009) Bo He et al.   CELL RESEARCH

Linking folding and binding

(2009) Peter E Wright et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Electrospray: From ions in solution to ions in the gas phase, what we know now

(2009) Paul Kebarle et al.   MASS SPECTROMETRY REVIEWS

Charge neutralization and collapse of the C-terminal tail of alpha-synuclein at low pH

(2009) Sebastian McClendon et al.   PROTEIN SCIENCE

Order propensity of an intrinsically disordered protein, the cyclin-dependent-kinase inhibitor Sic1

(2009) Stefania Brocca et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Structural insights on physiological functions and pathological effects of α-synuclein

(2008) Marco Bisaglia et al.   FASEB JOURNAL

Optical Reporters for the Conformation of  -Synuclein Reveal a Specific Interaction with Mitochondria

(2008) K. Nakamura et al.   JOURNAL OF NEUROSCIENCE

Insights into virus capsid assembly from non-covalent mass spectrometry

(2008) Victoria L. Morton et al.   MASS SPECTROMETRY REVIEWS

Fuzzy complexes: polymorphism and structural disorder in protein–protein interactions

(2007) Peter Tompa et al.   TRENDS IN BIOCHEMICAL SCIENCES