Controlling Epileptiform Activity with Organic Electronic Ion Pumps

Retinal Prosthetics, Optogenetics, and Chemical Photoswitches

(2014) Robert Marc et al.   ACS Chemical Neuroscience

On the nature of seizure dynamics

(2014) Viktor K. Jirsa et al.   BRAIN

Gene therapy in epilepsy—is it time for clinical trials?

(2014) Dimitri M. Kullmann et al.   Nature Reviews Neurology

New avenues for anti-epileptic drug discovery and development

(2013) Wolfgang Löscher et al.   NATURE REVIEWS DRUG DISCOVERY

A Gαs DREADD Mouse for Selective Modulation of cAMP Production in Striatopallidal Neurons

(2013) Martilias S Farrell et al.   NEUROPSYCHOPHARMACOLOGY

On-demand optogenetic control of spontaneous seizures in temporal lobe epilepsy

(2013) Esther Krook-Magnuson et al.   Nature Communications

In vivo recordings of brain activity using organic transistors

(2013) Dion Khodagholy et al.   Nature Communications

Fast targeted gene transfection and optogenetic modification of single neurons using femtosecond laser irradiation

(2013) Maciej Antkowiak et al.   Scientific Reports

Closed-loop optogenetic control of thalamus as a tool for interrupting seizures after cortical injury

(2012) Jeanne T Paz et al.   NATURE NEUROSCIENCE

Optogenetic investigation of neural circuits underlying brain disease in animal models

(2012) Kay M. Tye et al.   NATURE REVIEWS NEUROSCIENCE

Highly Conformable Conducting Polymer Electrodes for In Vivo Recordings

(2011) Dion Khodagholy et al.   ADVANCED MATERIALS

Grateful DREADDs: Engineered Receptors Reveal How Neural Circuits Regulate Behavior

(2011) Susan M Ferguson et al.   NEUROPSYCHOPHARMACOLOGY

Drug-Resistant Epilepsy

(2011) Patrick Kwan et al.   NEW ENGLAND JOURNAL OF MEDICINE

In search of models of pharmacoresistant epilepsy

(2010) Abdul Wahab et al.   EPILEPSIA

Optogenetics

(2010) Karl Deisseroth   NATURE METHODS

Directed molecular evolution of DREADDs: a generic approach to creating next-generation RASSLs

(2010) Shuyun Dong et al.   Nature Protocols

Translating Electronic Currents to Precise Acetylcholine–Induced Neuronal Signaling Using an Organic Electrophoretic Delivery Device

(2009) Klas Tybrandt et al.   ADVANCED MATERIALS

Organic electronics for precise delivery of neurotransmitters to modulate mammalian sensory function

(2009) Daniel T. Simon et al.   NATURE MATERIALS

Key factors in the discovery and development of new antiepileptic drugs

(2009) Meir Bialer et al.   NATURE REVIEWS DRUG DISCOVERY

Neuronal and non-neuronal GABA transporters as targets for antiepileptic drugs

(2009) Karsten K. Madsen et al.   PHARMACOLOGY & THERAPEUTICS

Standard antiepileptic drugs fail to block epileptiform activity in rat organotypic hippocampal slice cultures

(2008) K Albus et al.   BRITISH JOURNAL OF PHARMACOLOGY