Article
Pharmacology & Pharmacy
Thomas Jensen, Kevin Kris Warnakula Olesen, Raffaele De Caterina, Morten Wurtz, Steen Dalby Kristensen, Michael Maeng
Summary: In patients with atrial fibrillation, diabetes mellitus increases the risk of ischemic stroke regardless of treatment. Both insulin-treated and noninsulin-treated diabetes patients have higher risks of ischemic stroke compared to non-diabetes patients. There is no significant difference in risk between insulin-treated and noninsulin-treated diabetes patients.
VASCULAR PHARMACOLOGY
(2021)
Editorial Material
Medicine, General & Internal
[Anonymous]
Summary: This interactive feature discusses screening for atrial fibrillation in asymptomatic older adults through a case vignette and two essays that present arguments for and against screening.
NEW ENGLAND JOURNAL OF MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Andreas S. Papazoglou, Anastasios Kartas, Athanasios Samaras, Ioannis Vouloagkas, Eleni Vrana, Dimitrios V. Moysidis, Evangelos Akrivos, Georgios Kotzampasis, Amalia Baroutidou, Anastasios Papanastasiou, Evangelos Liampas, Michail Botis, Efstratios Karagiannidis, Nikolaos Stalikas, Haralambos Karvounis, Apostolos Tzikas, George Giannakoulas
Summary: The presence of diabetes mellitus on top of atrial fibrillation was associated with increased risk of all-cause mortality and cardiovascular mortality. Lower HbA1c levels were independently related to better survival rates in patients with atrial fibrillation and diabetes mellitus.
CARDIOVASCULAR DIABETOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Louise Kezerle, Meytal Avgil Tsadok, Amichay Akriv, Adi Berliner Senderey, Asaf Bachrach, Maya Leventer-Roberts, Moti Haim
Summary: Pre-diabetes is associated with an increased risk of stroke in patients with nonvalvular atrial fibrillation (NVAF), even after adjustment for other risk factors. Diabetes confers an even higher risk of stroke compared to normoglycemic individuals. Mortality risk is higher in individuals with diabetes but not in those with pre-diabetes.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Medicine, General & Internal
Albert Youngwoo Jang, Jeongduk Seo, Yae Min Park, Yong Hoon Shin, Joonpyo Lee, Pyung Chun Oh, Woong Chol Kang, Wook-Jin Chung, Jeonggeun Moon
Summary: This study found that blood type of atrial fibrillation patients is associated with the occurrence of major adverse cerebrovascular events. AB blood type is associated with higher MACE rates compared to non-AB blood types.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Mu Chen, Jian Sun, Qun-Shan Wang, Peng-Pai Zhang, Wei Li, Rui Zhang, Bin-Feng Mo, Yi-Chi Yu, Xingxing Cai, Mei Yang, Xiao-Ming Lian, Yan Zhao, Changqi Gong, Yi Yu, Bo Liu, Xiangfei Feng, Qiufen Lu, Yi-Gang Li
Summary: This study evaluated the procedural safety and long-term outcome of the combined procedure of catheter ablation and left atrial appendage closure in patients with atrial fibrillation. The results showed that the combined procedure was safe and effective in controlling heart rhythm and reducing the risk of strokes.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2022)
Article
Medicine, General & Internal
Jacopo Francesco Imberti, Davide Antonio Mei, Marco Vitolo, Niccolo Bonini, Marco Proietti, Tatjana Potpara, Gregory Y. H. Lip, Giuseppe Boriani
Summary: Clinical practice in atrial fibrillation patient management is constantly evolving. Various new guidelines have been published in the past few years, and they differ in key elements such as thromboembolic risk assessment, oral anticoagulants prescription, bleeding risk evaluation, and integrated patient management. The importance of an integrated and multidisciplinary approach to patient care is emerging.
EUROPEAN JOURNAL OF INTERNAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Hifza Buhari, Jiming Fang, Lu Han, Peter C. Austin, Paul Dorian, Cynthia A. Jackevicius, Amy Y. X. Yu, Moira K. Kapral, Sheldon M. Singh, Karen Tu, Dennis T. Ko, Clare L. Atzema, Emelia J. Benjamin, Douglas S. Lee, Husam Abdel-Qadir
Summary: This study aimed to examine the relationship between sex differences in age and cardiovascular care and stroke in atrial fibrillation (AF). The results showed that females had higher rates of stroke in AF even after adjusting for other factors. Older age and inequities in cardiovascular care partially explained the higher stroke rates in females with AF.
EUROPEAN HEART JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Yu-Sheng Lin, Hsin-Yu Tsai, Chia-Ying Lin, Victor Chien-Chia Wu, Tien-Hsing Chen, Teng-Yao Yang, Victor Aboyans, Mien-Cheng Chen
Summary: Patients with hyperthyroidism-related atrial fibrillation have a lower incidence of thromboembolic events compared to those without hyperthyroidism. This suggests that the presence of hyperthyroidism in atrial fibrillation patients may have a protective effect against thromboembolic events.
Article
Medicine, General & Internal
Pawel Wankowicz, Przemyslaw Nowacki, Monika Golab-Janowska
Summary: The study found that compared to patients without AF, patients with nonvalvular atrial fibrillation (NVAF) and ischemic stroke (IS) had a higher proportion of smokers, hypertension, history of previous stroke, dyslipidemia, coronary heart disease, more female patients, higher incidence of diabetes mellitus, and older patients. This suggests a need for thorough monitoring of post-ischemic stroke patients with other risk factors that could lead to AF development.
ARCHIVES OF MEDICAL SCIENCE
(2021)
Article
Medicine, General & Internal
Elin Danielsen Lunde, Albert Marni Joensen, Kirsten Fonager, Soren Lundbye-Christensen, Soren Paaske Johnsen, Mogens Lytken Larsen, Gregory YH Lip, Sam Riahi
Summary: This study found that in Denmark, patients with low income, low education, and living alone had a lower chance of being initiated with OAC therapy. The inequality in OAC initiation reduced around 2011 when more detailed clinical guidelines were implemented.
Review
Cardiac & Cardiovascular Systems
Adrian D. Elliott, Melissa E. Middeldorp, Isabelle C. Van Gelder, Christine M. Albert, Prashanthan Sanders
Summary: The global prevalence of atrial fibrillation (AF) has significantly increased over the past three decades to approximately 60 million cases. Various risk factors, including lifestyle choices, can modify the lifetime risk of AF. This review provides evidence on the epidemiology of AF, both non-modifiable and modifiable risk factors, and strategies for primary and secondary prevention. It also discusses potential interventions to reduce the frequency and severity of subsequent AF episodes and proposes strategies and global policy changes for the prevention and management of AF.
NATURE REVIEWS CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Sergio Raposeiras-Roubin, Emad Abu-Assi, Alvaro Marchan, Tamara Fernandez-Sanz, Cristina Barreiro-Pardal, Isabel Munoz Pousa, Pablo Dominguez Erquicia, Ana Ledo-Pineiro, Inmaculada Gonzalez-Bermudez, Maria Melendo Viu, Andres Iniguez-Romo
Summary: The study evaluated the predictive ability of CHA(2)DS(2)-VASc and HAS-BLED scores in patients with AF and cancer. It found that in patients with cancer not receiving anticoagulation therapy, the CHA(2)DS(2)-VASc score had poor predictive ability compared to those without cancer, while the HAS-BLED score performed similarly in patients with and without cancer.
AMERICAN JOURNAL OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
George R. Marzouka, Harold Rivner, Vijay Mehta, Juan Lopez, Igor Vaz, Fei Tang, Hemant Ishwaran, Jeffrey J. Goldberger
Summary: The study showed that the CHA(2)DS(2)-VASc score can effectively stratify the risk of stroke in HF patients and predict the occurrence of stroke in HF patients, regardless of whether they have AF. Patients with higher CHA(2)DS(2)-VASc scores, with or without AF, have increased risk of stroke, thromboembolism, and death.
AMERICAN JOURNAL OF CARDIOLOGY
(2021)
Article
Medicine, General & Internal
Jwan A. Naser, Sorin V. Pislaru, Marius N. Stan, Grace Lin
Summary: The study aims to describe the incidence, risk factors, and outcomes of atrial fibrillation (AF) in Graves disease (GD). The results showed that AF occurred in 139 out of 1371 GD patients, with 32 cases of late-onset AF. Risk factors for early AF were age, overt hyperthyroidism, and male sex, while risk factors for late AF were age, chronic obstructive pulmonary disease, and heart failure. GD-related AF was associated with higher mortality, acute coronary syndrome/stable angina events, and cardiac hospitalizations.
MAYO CLINIC PROCEEDINGS
(2023)