Article
Cardiac & Cardiovascular Systems
Jarl Emanuel Strange, Daniel Molager Christensen, Caroline Sindet-Pedersen, Morten Schou, Alexander Christian Falkentoft, Lauge Ostergaard, Jawad Haider Butt, Peter Laursen Graversen, Lars Kober, Gunnar Gislason, Jonas Bjerring Olesen, Emil Loldrup Fosbol
Summary: Frailty is strongly associated with time in hospital and mortality among patients undergoing transcatheter aortic valve replacement. Higher frailty levels are linked to longer hospital stays and increased risk of death within one year. Strategies aimed at preventing hospitalization among frail patients could be beneficial in reducing the burden of care.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2023)
Article
Cardiac & Cardiovascular Systems
Flavien Vincent, Julien Ternacle, Tom Denimal, Mylene Shen, Bjorn Redfors, Cedric Delhaye, Matheus Simonato, Nicolas Debry, Basile Verdier, Bahira Shahim, Thibault Pamart, Hugues Spillemaeker, Guillaume Schurtz, Francois Pontana, Vinod H. Thourani, Philippe Pibarot, Eric Van Belle
Summary: TAVR is rapidly expanding its indications, but faces technical challenges and knowledge gaps when dealing with patients with bicuspid aortic valve (BAV). Physicians need to understand the BAV anatomy and TAVR procedure planning comprehensively to guide treatment decisions.
Article
Radiology, Nuclear Medicine & Medical Imaging
Rydhwana Hossain, Lydia Chelala, Ghassan Sleilaty, Sagar Amin, Jenanan Vairavamurthy, Rong Chen, Anuj Gupta, Jean Jeudy, Charles White
Summary: This study retrospectively evaluated imaging features of right heart failure on pre-TAVR CT for 505 patients and found that characteristics such as pericardial effusion size and main pulmonary artery size were associated with increased mortality within 1 year after the procedure. Multivariate logistic regression analysis showed that these features were independent predictors of death, even after adjusting for the Society of Thoracic Surgeons score.
AMERICAN JOURNAL OF ROENTGENOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Shinichi Fukuhara, Chan Tran N. Nguyen, Karen M. Kim, Bo Yang, Gorav Ailawadi, Himanshu J. Patel, G. Michael Deeb
Summary: Despite the rapid adoption of transcatheter aortic valve replacement (TAVR), there are limited data on aortic valve reintervention after initial TAVR. A retrospective study reviewed 1487 patients who underwent TAVR and found that 24 (1.6%) required aortic valve reintervention. Most patients were deemed unsuitable for repeat TAVR due to concurrent cardiac procedures, unfavorable anatomy, or endocarditis. Therefore, careful assessment of TAVR repeatability should be considered in the initial TAVR evaluation, especially for younger patients who may require aortic valve reintervention.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2023)
Review
Medicine, General & Internal
Pierfranco Terrosu, Alessandro Boccanelli, Giuseppe Sabino, Paolo Alboni, Samuele Baldasseroni, Mario Bo, Giovambattista Desideri, Niccolo Marchionni, Giuseppe Palazzo, Renzo Rozzini, Andrea Ungar, Francesco Vetta, Giovanni Zito
Summary: Transcatheter aortic valve replacement (TAVR) has become the standard treatment for symptomatic severe aortic stenosis. Frailty and medical comorbidities in the elderly population are significant predictors of outcomes after TAVR.
Review
Medicine, General & Internal
Lorenzo Braghieri, Simrat Kaur, Christopher K. Black, Paul C. Cremer, Shinya Unai, Samir R. Kapadia, Amgad Mentias
Summary: Transcatheter aortic valve replacement (TAVR) is increasingly used as the main treatment for aortic stenosis compared to surgical aortic valve replacement (SAVR). However, TAVR-related infective endocarditis (TAVR-IE) is expected to be more common in younger patients. Therefore, it is important for clinicians to be familiar with common presentations, major risk factors, diagnostic pitfalls, therapeutic approaches, and prevention of TAVR-IE.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Keti Vitanova, Syed Zaid, Gilbert H. L. Tang, Tsuyoshi Kaneko, Vinayak N. Bapat, Thomas Modine, EXPLANT TAVR Investigators
Summary: In this study, the outcomes of AVR and root replacement after TAVR explantation were compared. The results showed no differences in short-term mortality and morbidities between the two groups, although they had different clinical characteristics.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Soojung Park, Yongwon Cho, Yu-Whan Oh, Minseok Ko, Do-Sun Lim, Cheol Woong Yu, Seong-Mi Park, Mi-Na Kim, Sung Ho Hwang
Summary: The objective of this study was to explore the relationship between spectral computed tomography (CT) measured iodine concentration and strength of aortic valvular calcification (AVC) in patients with aortic valve stenosis (AVS). The study found that iodine concentration was independently associated with the reduction percentage of AVC. Additionally, when an optimal iodine concentration cutoff point was set at 4 mg/mL, it could accurately assess fragile AVC with a reduction percentage greater than 18.5%.
EUROPEAN RADIOLOGY
(2023)
Editorial Material
Cardiac & Cardiovascular Systems
Alessandra Francica, Mikhail Dodonov, Filippo Tonelli, Gaetano Paolino, Gabriele Pesarini, Flavio Ribichini, Giuseppe Faggian, Francesco Onorati
Summary: This report describes a rare case of early postoperative fatal ViV-TAVR thrombosis despite adequate anticoagulation in addition to dual antiplatelet therapy.
ANNALS OF THORACIC SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Alberto Alperi, Josep Rodes-Cabau, Matheus Simonato, Didier Tchetche, Gaetan Charbonnier, Henrique B. Ribeiro, Azeem Latib, Matteo Montorfano, Marco Barbanti, Sabine Bleiziffer, Bjorn Redfors, Mohamed Abdel-Wahab, Abdelhakim Allali, Giuseppe Bruschi, Massimo Napodano, Marco Agrifoglio, Anna Sonia Petronio, Cristina Giannini, Albert Chan, Ran Kornowski, Nili Schamroth Pravda, Matti Adam, Alessandro Iadanza, Stephane Noble, Andrew Chatfield, Magdalena Erlebach, Joerg Kempfert, Timm Ubben, Harindra Wijeysundera, Moritz Seiffert, Thomas Pilgrim, Won-Keun Kim, Luca Testa, David Hildick-Smith, Roberto Nerla, Claudia Fiorina, Christina Brinkmann, Lars Conzelmann, Didier Champagnac, Francesco Saia, Henrik Nissen, Hafid Amrane, Brian Whisenant, Jasmin Shamekhi, Lars Sondergaard, John G. Webb, Danny Dvir
Summary: In a large series of ViV-TAVR procedures, the incidence of periprocedural PPI was relatively low and decreased with the use of new-generation THV systems. Older age, larger THV size, and previous right bundle branch block were associated with an increased risk of PPI. Although there were no significant differences in 30-day mortality between the PPI and no-PPI groups, PPI patients exhibited a trend toward higher mortality risk at follow-up.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Review
Pharmacology & Pharmacy
Harish Sharma, Shazia Afzal, Juergen Leick, Nikos Werner, Sagar N. Doshi, M. Adnan Nadir
Summary: This review aims to provide clinicians with guidance on the optimal antithrombotic strategy post-TAVR, taking into consideration different patient populations and the limitations of existing guidelines.
PHARMACOLOGY & THERAPEUTICS
(2023)
Article
Cardiac & Cardiovascular Systems
Marina Urena, Alec Vahanian, Eric Brochet, Gregory Ducrocq, Bernard Iung, Dominique Himbert
Summary: The clinical use of TMVR using transcatheter aortic valves is limited to patients with failing bioprostheses or rings, and mitral valve disease associated with severe mitral annulus calcification. While valve-in-valve TMVR seems to be a reasonable alternative to surgery for high-risk patients, there is less evidence supporting valve-in-ring and valve-in-mitral annulus calcification interventions.
Article
Geriatrics & Gerontology
Anne Sophie Bobet, Celine Brouessard, Thierry Le Tourneau, Thibaut Manigold, Laure de Decker, Anne-Sophie Boureau
Summary: The study found that screening for major neurocognitive disorders before TAVR surgery helps reduce hospital stay. The implementation of individualized-care plans proposed after geriatric assessment was poor, indicating a need for improvement in compliance.
Article
Cardiac & Cardiovascular Systems
Keita Koseki, Sung-Han Yoon, Danon Kaewkes, Ofir Koren, Vivek Patel, Isic Kim, Rohan Sharma, Navjot Sekhon, Tarun Chakravarty, Mamoo Nakamura, Wen Cheng, Issei Komuro, Raj Makkar
Summary: The Geriatric Nutritional Risk Index (GNRI) is an important surrogate marker for predicting prognosis and mortality in patients undergoing transcatheter aortic valve implantation (TAVI). Subgroup analyses showed that GNRI retained its predictive value stratified by age and Society of Thoracic Surgeons (STS) score.
AMERICAN JOURNAL OF CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Amgad Mentias, Marwan Saad, Milind Y. Desai, Amar Krishnaswamy, Venu Menon, Phillip A. Horwitz, Samir Kapadia, Mary Vaughan Sarrazin
Summary: The study compared outcomes of transcatheter aortic valve replacement (TAVR) and surgical aortic valve replacement (SAVR) in patients with rheumatic aortic stenosis (AS), as well as TAVR in nonrheumatic AS. The results showed similar mortality rates between TAVR and SAVR for rheumatic AS patients, suggesting that TAVR could be a viable alternative to traditional surgery in this patient population.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
