Design, syntheses and biological evaluation of natural product aiphanol derivatives and analogues: Discovery of potent anticancer agents

Discovery of Anticancer Agents of Diverse Natural Origin

(2022) Leslie N. Aldrich et al.   JOURNAL OF NATURAL PRODUCTS

Aiphanol, a multi-targeting stilbenolignan, potently suppresses mouse lymphangiogenesis and lymphatic metastasis

(2022) Shan-mei Chen et al.   ACTA PHARMACOLOGICA SINICA

Properties of FDA-approved small molecule protein kinase inhibitors: a 2021 update

(2021) Robert Roskoski   PHARMACOLOGICAL RESEARCH

Molecular Targeting of Epidermal Growth Factor Receptor (EGFR) and Vascular Endothelial Growth Factor Receptor (VEGFR)

(2021) Nichole E. M. Kaufman et al.   MOLECULES

Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019

(2020) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

The modification of natural products for medical use

(2017) Zongru Guo   Acta Pharmaceutica Sinica B

Gram Scale Syntheses of (−)-Incarvillateine and Its Analogs. Discovery of Potent Analgesics for Neuropathic Pain

(2016) Bin Huang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cyclooxygenase-2 blockade can improve efficacy of VEGF-targeting drugs

(2015) Isabel Ben-Batalla et al.   Oncotarget

Simultaneous Inhibition of EGFR/VEGFR and Cyclooxygenase-2 Targets Stemness-Related Pathways in Colorectal Cancer Cells

(2015) Araceli Valverde et al.   PLoS One

Combining sorafenib with celecoxib synergistically inhibits tumor growth of non-small cell lung cancer cells in vitro and in vivo

(2014) HONG ZHANG et al.   ONCOLOGY REPORTS

COX-2 Inhibition Potentiates Antiangiogenic Cancer Therapy and Prevents Metastasis in Preclinical Models

(2014) L. Xu et al.   Science Translational Medicine

Cox-2 inhibition enhances the activity of sunitinib in human renal cell carcinoma xenografts

(2013) X Wang et al.   BRITISH JOURNAL OF CANCER

Chemical Constituents from the Rhizomes of Smilax glabra and Their Antimicrobial Activity

(2013) Shuo Xu et al.   MOLECULES

Novel Combination of Sorafenib and Celecoxib Provides Synergistic Anti-Proliferative and Pro-Apoptotic Effects in Human Liver Cancer Cells

(2013) Melchiorre Cervello et al.   PLoS One

New C-23 modified of silybin and 2,3-dehydrosilybin: Synthesis and preliminary evaluation of antioxidant properties

(2011) Armando Zarrelli et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The role of bevacizumab in colorectal cancer: understanding its benefits and limitations

(2011) Karen Mulder et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Mitochondrial apoptosis contributes to the anti-cancer effect of Smilax glabra Roxb.

(2011) Yujing Gao et al.   TOXICOLOGY LETTERS

Chemoenzymatic preparative separation of silybins A and B

(2009) Vladimír Křen et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC