Long-term sevoflurane exposure resulted in temporary rather than lasting cognitive impairment in Drosophila

Maternal anesthesia with sevoflurane during the mid-gestation induces social interaction deficits in offspring C57BL/6 mice

(2021) Qingcai Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A new mechanism of POCD caused by sevoflurane in mice: cognitive impairment induced by cross-dysfunction of iron and glucose metabolism

(2021) Xing Ge et al.   Aging-US

Cyclophilin D Contributes to Anesthesia Neurotoxicity in the Developing Brain

(2020) Yiying Zhang et al.   Frontiers in Cell and Developmental Biology

Neonatal Exposure to Anesthesia Leads to Cognitive Deficits in Old Age: Prevention with Intranasal Administration of Insulin in Mice

(2020) Chun-Ling Dai et al.   NEUROTOXICITY RESEARCH

Mitochondrial Complex I Mutations Predispose Drosophila to Isoflurane Neurotoxicity

(2020) Zachariah P. G. Olufs et al.   ANESTHESIOLOGY

Neonatal sevoflurane exposure induces impulsive behavioral deficit through disrupting excitatory neurons in the medial prefrontal cortex in mice

(2020) Linghua Xie et al.   Translational Psychiatry

Early Childhood General Anesthesia and Neurodevelopmental Outcomes in the Avon Longitudinal Study of Parents and Children Birth Cohort

(2020) Graham J. Walkden et al.   ANESTHESIOLOGY

Early childhood general anesthesia exposure associated with later developmental delay: A national population-based cohort study

(2020) Yu-Pin Feng et al.   PLoS One

Sevoflurane increases intracellular calcium to induce mitochondrial injury and neuroapoptosis

(2020) Xiaoqiu Zhu et al.   TOXICOLOGY LETTERS

Sevoflurane exposure has minimal effect on cognitive function and does not alter microglial activation in adult monkeys

(2019) Jennifer L. Walters et al.   NEUROTOXICOLOGY

Neurodevelopmental outcome at 5 years of age after general anaesthesia or awake-regional anaesthesia in infancy (GAS): an international, multicentre, randomised, controlled equivalence trial

(2019) Mary Ellen McCann et al.   LANCET

Cistanches alleviates sevoflurane‐induced cognitive dysfunction by regulating PPAR‐γ‐dependent antioxidant and anti‐inflammatory in rats

(2019) Sheng Peng et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Hemin treatment protects neonatal rats from sevoflurane-induced neurotoxicity via the phosphoinositide 3-kinase/Akt pathway

(2019) Fan Yang et al.   LIFE SCIENCES

Neuropsychological and Behavioral Outcomes after Exposure of Young Children to Procedures Requiring General Anesthesia

(2018) David O. Warner et al.   ANESTHESIOLOGY

Persistent alteration in behavioural reactivity to a mild social stressor in rhesus monkeys repeatedly exposed to sevoflurane in infancy

(2018) J. Raper et al.   BRITISH JOURNAL OF ANAESTHESIA

Genetic variability affects absolute and relative potencies and kinetics of the anesthetics isoflurane and sevoflurane in Drosophila melanogaster

(2018) Zachariah P. G. Olufs et al.   Scientific Reports

Minocycline attenuates sevoflurane-induced cell injury via activation of Nrf2

(2017) Yue Tian et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

An inhibitory mono-ubiquitylation of the Drosophila initiator caspase Dronc functions in both apoptotic and non-apoptotic pathways

(2017) Hatem Elif Kamber Kaya et al.   PLoS Genetics

In Vivo Monitoring of Sevoflurane-induced Adverse Effects in Neonatal Nonhuman Primates Using Small-animal Positron Emission Tomography

(2016) Xuan Zhang et al.   ANESTHESIOLOGY

A Population-based Study Evaluating the Association between Surgery in Early Life and Child Development at Primary School Entry

(2016) James D. O’Leary et al.   ANESTHESIOLOGY

Association Between a Single General Anesthesia Exposure Before Age 36 Months and Neurocognitive Outcomes in Later Childhood

(2016) Lena S. Sun et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Multiple Anesthetic Exposure in Infant Monkeys Alters Emotional Reactivity to an Acute Stressor

(2015) Jessica Raper et al.   ANESTHESIOLOGY

Effect of the inhaled anesthetics isoflurane, sevoflurane and desflurane on the neuropathogenesis of Alzheimer’s disease (Review)

(2015) JUE JIANG et al.   Molecular Medicine Reports

Sevoflurane inhibits the antioxidant capacity of erythrocytes

(2015) BO YE et al.   Experimental and Therapeutic Medicine

Long-term dietary exposure to low concentration of dichloroacetic acid promoted longevity and attenuated cellular and functional declines in aged Drosophila melanogaster

(2014) Ashutosh Pandey et al.   AGE

Sevoflurane causes neuronal apoptosis and adaptability changes of neonatal rats

(2013) S. Q. ZHENG et al.   ACTA ANAESTHESIOLOGICA SCANDINAVICA

Developmentally programmed cell death in Drosophila

(2013) Donna Denton et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Risk of dementia after anaesthesia and surgery

(2013) Pin-Liang Chen et al.   BRITISH JOURNAL OF PSYCHIATRY

Comparison of the Neuroapoptotic Properties of Equipotent Anesthetic Concentrations of Desflurane, Isoflurane, or Sevoflurane in Neonatal Mice

(2011) George K. Istaphanous et al.   ANESTHESIOLOGY

Genotoxic damage induced by isopropanol in germinal and somatic cells of Drosophila melanogaster

(2011) Ana María Palermo et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Structure of the Drosophila Apoptosome at 6.9 Å Resolution

(2011) Shujun Yuan et al.   STRUCTURE

Genetic control of programmed cell death (apoptosis) in Drosophila

(2010) Dongbin Xu et al.   FLY

Antimicrobial Peptides Increase Tolerance to Oxidant Stress inDrosophila melanogaster

(2010) Huiwen W. Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Unfolded Protein Response Protects from Tau Neurotoxicity In Vivo

(2010) Carin A. Loewen et al.   PLoS One

Inhibition of p75 Neurotrophin Receptor Attenuates Isoflurane-mediated Neuronal Apoptosis in the Neonatal Central Nervous System

(2009) Brian P. Head et al.   ANESTHESIOLOGY

The Common Inhalational Anesthetic Sevoflurane Induces Apoptosis and Increases β-Amyloid Protein Levels

(2009) Yuanlin Dong et al.   ARCHIVES OF NEUROLOGY

Parametric and genetic analysis ofDrosophilaappetitive long-term memory and sugar motivation

(2009) J. Colomb et al.   GENES BRAIN AND BEHAVIOR

Inhalational anesthesia vs total intravenous anesthesia (TIVA) for pediatric anesthesia

(2009) JERROLD LERMAN et al.   PEDIATRIC ANESTHESIA

The Bax/Bak ortholog in Drosophila, Debcl, exerts limited control over programmed cell death

(2008) K. A. Galindo et al.   DEVELOPMENT

Rapid Consolidation to a radish and Protein Synthesis-Dependent Long-Term Memory after Single-Session Appetitive Olfactory Conditioning in Drosophila

(2008) M. J. Krashes et al.   JOURNAL OF NEUROSCIENCE