Article
Multidisciplinary Sciences
Xiangyong Kong, Jun Yin, Hongwu Chen, Jiawei Wu, Xiaofan Yu, Ningtian Zhou, Likun Ma
Summary: This study analyzed the risk factors, management, and in-hospital outcomes of intermediate-risk NSTE-ACS patients in different time windows for revascularization. The results showed that the incidence of in-hospital major adverse cardiovascular events (MACEs) was lower in patients who underwent revascularization within 48 hours.
SCIENTIFIC REPORTS
(2022)
Article
Cardiac & Cardiovascular Systems
Konstantinos C. Koskinas, Baris Gencer, David Nanchen, Mattia Branca, David Carballo, Roland Klingenberg, Manuel R. Blum, Sebastian Carballo, Olivier Muller, Christian M. Matter, Thomas F. Luscher, Nicolas Rodondi, Dik Heg, Matthias Wilhelm, Lorenz Raber, Francois Mach, Stephan Windecker
Summary: This study analyzed a cohort of acute coronary syndrome patients in Switzerland and found that based on the 2019 ESC/EAS guidelines, half of the patients were potentially eligible for PCSK9i treatment, compared to a three-fold lower eligibility rate based on the 2018 ACC/AHA guidelines.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Sripal Bangalore, Eric R. Bates, Theresa M. Beckie, James M. Bischoff, John A. Bittl, Mauricio G. Cohen, J. Michael DiMaio, Creighton W. Don, Stephen E. Fremes, Mario F. Gaudino, Zachary D. Goldberger, Michael C. Grant, Jang B. Jaswal, Paul A. Kurlansky, Roxana Mehran, Thomas S. Metkus, Lorraine C. Nnacheta, Sunil V. Rao, Frank W. Sellke, Garima Sharma, Celina M. Yong, Brittany A. Zwischenberger, Patrick T. O'Gara, Joshua A. Beckman, Glenn N. Levine, Sana M. Al-Khatib, Anastasia L. Armbruster, Kim K. Birtcher, Joaquin E. Cigarroa, Lisa de las Fuentes, Anita Deswal, Dave L. Dixon, Lee A. Fleisher, Federico Gentile, Zachary D. Goldberger, Bulent Gorenek, Norrisa Haynes, Adrian F. Hernandez, Mark A. Hlatky, Jose A. Joglar, W. Schuyler Jones, Joseph E. Marine, Daniel B. Mark, Debabrata Mukherjee, Latha P. Palaniappan, Mariann R. Piano, Tanveer Rab, Erica S. Spatz, Jacqueline E. Tamis-Holland, Duminda N. Wijeysundera, Y. Joseph Woo
Summary: This article introduces the importance and application of coronary artery revascularization guidelines, which provide a patient-centric approach for treating patients with significant coronary artery disease. The guidelines are supported by relevant literature.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Harmony R. Reynolds, C. Noel Bairey Merz, Colin Berry, Rohit Samuel, Jacqueline Saw, Nathaniel R. Smilowitz, Ana Carolina do A. H. de Souza, Robert Sykes, Viviany R. Taqueti, Janet Wei
Summary: Ischemic heart disease is the leading cause of mortality in women and requires gender-specific risk stratification for prevention, diagnosis, and treatment. Recent research has improved understanding of cardiovascular disease in women, including mechanisms of ischemia with no obstructive coronary arteries and myocardial infarction with no obstructive coronary arteries. Despite progress, sex differences in ischemic heart disease outcomes persist.
CIRCULATION RESEARCH
(2022)
Article
Cell Biology
Shanshan Liu, Shujing Wu, Jingya Niu, Ruizhi Zheng, Lizhan Bie, Zhuojun Xin, Shuangyuan Wang, Hong Lin, Zhiyun Zhao, Mian Li, Tiange Wang, Min Xu, Jieli Lu, Yuhong Chen, Yiping Xu, Yufang Bi, Weiqing Wang, Guang Ning, Yu Xu
Summary: The study found that individuals with stage 1 hypertension defined by the 2017 ACC/AHA guideline had a 1.48-fold increased risk of developing arterial stiffness compared to those with normal blood pressure. This association was more evident in adults aged 40-59 years. A systolic BP of 130 to 139 mmHg was significantly associated with arterial stiffness.
Article
Medicine, General & Internal
Tobias F. S. Pustjens, Marijke J. C. Timmermans, Saman Rasoul, Arnoud W. J. van't Hof
Summary: The study found that NSTE-ACS patients with MVD undergoing MV-PCI and CO-PCI had similar mortality rates at long-term follow-up, but the MV-PCI group showed improved event-free survival in terms of fewer coronary reinterventions.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Jose R. Medina-Inojosa, Virend K. Somers, Mariana Garcia, Randal J. Thomas, Thomas Allison, Rajeev Chaudry, Christina M. Wood-Wentz, Kent R. Bailey, Sharon L. Mulvagh, Francisco Lopez-Jimenez
Summary: This study tested the performance of PCE in predicting ASCVD risk in a community setting and found that values outside PCE ranges and statin medication initiation did not affect its predictive capabilities.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Fadia Mayyas, Khalid Ibrahim
Summary: Coronary artery disease (CAD) is a common, life-threatening condition associated with atherosclerosis. This study investigated how galectin-3, an inflammatory factor, is related to CAD and its severity. The findings suggest that elevated levels of galectin-3 in the blood are associated with a higher risk of CAD and the need for revascularization procedures. Galectin-3 could be a potential biomarker for assessing CAD risk and guiding treatment decisions.
AMERICAN JOURNAL OF CARDIOLOGY
(2023)
Review
Cardiac & Cardiovascular Systems
Denise Cristiana Faro, Claudio Laudani, Federica Giuseppa Agnello, Nicola Ammirabile, Simone Finocchiaro, Marco Legnazzi, Maria Sara Mauro, Placido Maria Mazzone, Giovanni Occhipinti, Carla Rochira, Lorenzo Scalia, Marco Spagnolo, Antonio Greco, Davide Capodanno
Summary: Multivessel disease (MVD) is common in patients with acute coronary syndromes (ACS) and is associated with poor outcomes and high mortality rates. Complete revascularization is beneficial for hemodynamically stable ACS patients with MVD, but there are still uncertainties regarding optimal timing and guidance strategies.
JACC-CARDIOVASCULAR INTERVENTIONS
(2023)
Article
Multidisciplinary Sciences
Carlos Daniel Rodriguez-Ariza, Alfredo Cabrera-Villamizar, Astrid Lorena Rodriguez-Pulido, Santiago Callegari, Natalia Alejandra Ossa Rodriguez, Monica Pinilla-Roncancio, Sergio Mauricio Moreno Lopez, Carlos Andres Sanchez-Vallejo
Summary: This study aimed to evaluate the discrimination and calibration of the ACC/AHA ASCVD risk score in predicting the 10-year risk of cardiovascular events in a Colombian population. The results showed that the ACC/AHA ASCVD score had good calibration and discrimination capacity in predicting the 10-year risk of cardiovascular events in a primary prevention cohort in a Colombian hospital.
SCIENTIFIC REPORTS
(2023)
Review
Cell Biology
Bradley Tucker, Kaivan Vaidya, Blake J. Cochran, Sanjay Patel
Summary: Periprocedural myocardial injury and myocardial infarction are common complications of percutaneous coronary intervention, associated with increased short- and long-term mortality. Inflammation levels before, during, and after the procedure are linked to higher rates of myonecrosis and future cardiovascular events. In addition to inflammation from underlying coronary disease, PCI itself triggers an acute inflammatory response.
Article
Cardiac & Cardiovascular Systems
Monica Verdoia, Filippo Viglione, Annalisa Boggio, Daniele Stefani, Nicolo Panarotto, Aurelio Malabaila, Roberta Rolla, Pier Luigi Solda, Alessandro Stecco, Alessandro Carriero, Giuseppe De Luca
Summary: This study aimed to assess the impact of vitamin D on cholesterol levels among patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention (pPCI). The results showed that lower levels of vitamin D were independently associated with a more atherogenic lipid profile.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2022)
Article
Medicine, General & Internal
Oreste Lanza, Nicola Cosentino, Claudia Lucci, Marta Resta, Mara Rubino, Valentina Milazzo, Monica De Metrio, Filippo Trombara, Jeness Campodonico, Jose Pablo Werba, Alice Bonomi, Giancarlo Marenzi
Summary: Prior statin therapy is associated with a better in-hospital clinical outcome in patients with STEMI undergoing primary PCI.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Multidisciplinary Sciences
Jangho Park, Sangwoo Park, Yong-Giun Kim, Soe Hee Ann, Hyun Woo Park, Jon Suh, Jae-Hyung Roh, Young-Rak Cho, Seungbong Han, Gyung-Min Park
Summary: An analysis of National Health Insurance data in Korea showed that pre-existing depression does not have a significant impact on mortality in patients with established coronary artery disease undergoing PCI. However, younger patients with angina and depression may have a higher risk of all-cause mortality.
SCIENTIFIC REPORTS
(2021)
Article
Medicine, General & Internal
Ada del Mar Carmona-Segovia, Maria Victoria Doncel-Abad, Victor M. Becerra-Munoz, Jorge Rodriguez-Capitan, Fernando Sabatel-Perez, Maria Flores-Lopez, Maria Jose Sanchez-Quintero, Dina Medina-Vera, Ana Isabel Molina-Ramos, Rajaa El Bekay, Jose Miguel Morales-Asencio, Maria Angullo-Gomez, Luis Garcia-Rodriguez, Lucia Palma-Marti, Francisco Javier Pavon-Moron, Manuel F. Jimenez-Navarro
Summary: This study aims to evaluate changes of clinical and biochemical parameters in older patients with multivessel coronary artery disease (MVCAD) undergoing revascularisation and to establish a prognostic stratification model for complete revascularization (CR) and incomplete revascularization (ICR).
