Journal
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
Volume 138, Issue 13, Pages 4314-4317Publisher
AMER CHEMICAL SOC
DOI: 10.1021/jacs.6b00976
Keywords
-
Categories
Funding
- Chinese Academy of Sciences
- National Natural Science Foundation of China [21222203, 21133011]
Ask authors/readers for more resources
A novel highly enantioselective amino-methylamination of conjugated dienes with aminals catalyzed by a chiral palladium complex ligated with BINOL-derived chiral diphosphinite has been successfully developed. This reaction proceeds via a Pd-catalyzed cascade C-N bond activation, aminomethylation, and asymmetric allylic amination reaction under mild reaction conditions, providing a unique and efficient strategy for the synthesis of enantiomerically pure allylic 1,3-diamines.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available