Hypericum Perforatum Hydroalcoholic Extract Mitigates Motor Dysfunction and is Neuroprotective in Intrastriatal 6-Hydroxydopamine Rat Model of Parkinson’s Disease

Screening for impact of popular herbs improving mental abilities on the transcriptional level of brain transporters

(2014) Przemyslaw M. Mrozikiewicz et al.   ACTA PHARMACEUTICA

St. John’s Wort Promotes Adipocyte Differentiation and Modulates NF-κB Activation in 3T3-L1 Cells

(2014) Tomoko Hatano et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Differential effects of intrastriatal 6-hydroxydopamine on cell number and morphology in midbrain dopaminergic subregions of the rat

(2014) Michelle Healy-Stoffel et al.   BRAIN RESEARCH

Hypericum perforatum Modulates Apoptosis and Calcium Mobilization Through Voltage-Gated and TRPM2 Calcium Channels in Neutrophil of Patients with Behcet’s Disease

(2014) Mustafa Nazıroğlu et al.   JOURNAL OF MEMBRANE BIOLOGY

The neuroprotective potential of sinapic acid in the 6-hydroxydopamine-induced hemi-parkinsonian rat

(2014) Kobra Zare et al.   METABOLIC BRAIN DISEASE

Carnosine Exerts Neuroprotective Effect Against 6-Hydroxydopamine Toxicity in Hemiparkinsonian Rat

(2014) Siamak Afshin-Majd et al.   MOLECULAR NEUROBIOLOGY

Modulation of oxidative stress and Ca2+ mobilization through TRPM2 channels in rat dorsal root ganglion neuron by Hypericum perforatum

(2014) M. Nazıroğlu et al.   NEUROSCIENCE

Spinal Cord Stimulation Exerts Neuroprotective Effects against Experimental Parkinson’s Disease

(2014) Aiko Shinko et al.   PLoS One

Experimental study Effect of Hypericum perforatum on intraperitoneal adhesion formation in rats

(2013) Deniz Hızlı et al.   Archives of Medical Science

Neuroprotective Properties of Standardized Extracts of Hypericum perforatum on Rotenone Model of Parkinson’s Disease

(2013) M.A. del Rio et al.   CNS & Neurological Disorders-Drug Targets

Reduced Alzheimer’s Disease Pathology by St. John’s Wort Treatment is Independent of Hyperforin and Facilitated by ABCC1 and Microglia Activation in Mice

(2013) Jacqueline Hofrichter et al.   Current Alzheimer Research

Neuroinflammation and oxidative stress: Co-conspirators in the pathology of Parkinson’s disease

(2013) Juliet M. Taylor et al.   NEUROCHEMISTRY INTERNATIONAL

Neuroprotective effect of sulforaphane in 6-hydroxydopamine-lesioned mouse model of Parkinson's disease

(2013) Fabiana Morroni et al.   NEUROTOXICOLOGY

Isoliquiritigenin Isolated from LicoriceGlycyrrhiza uralensisPrevents 6-Hydroxydopamine-Induced Apoptosis in Dopaminergic Neurons

(2012) Cheol Kyu HWANG et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

SNP-Mediated Neuroprotection under Glucose Deprivation Is Enhanced by Hypericum perforatum

(2012) Maria Munoz et al.   CNS & Neurological Disorders-Drug Targets

Hyperoside protects primary rat cortical neurons from neurotoxicity induced by amyloid β-protein via the PI3K/Akt/Bad/BclXL-regulated mitochondrial apoptotic pathway

(2011) Ke-Wu Zeng et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Effect of St. John's Wort (Hypericum perforatum) treatment on restraint stress-induced behavioral and biochemical alteration in mice

(2010) Anil Kumar et al.   BMC Complementary and Alternative Medicine

Oral pelargonidin exerts dose-dependent neuroprotection in 6-hydroxydopamine rat model of hemi-parkinsonism

(2010) Mehrdad Roghani et al.   BRAIN RESEARCH BULLETIN

St. Johns Wort Components and the Brain: Uptake, Concentrations Reached and the Mechanisms Underlying Pharmacological Effects

(2010) Silvio Caccia et al.   CURRENT DRUG METABOLISM

Time-course of nigrostriatal neurodegeneration and neuroinflammation in the 6-hydroxydopamine-induced axonal and terminal lesion models of Parkinson's disease in the rat

(2010) S. Walsh et al.   NEUROSCIENCE

St. John’s Wort Constituents Modulate P-glycoprotein Transport Activity at the Blood-Brain Barrier

(2010) Melanie Ott et al.   PHARMACEUTICAL RESEARCH

St John’s Wort (Hypericum perforatum) in Major Depression

(2009) Richard C. Shelton   JOURNAL OF CLINICAL PSYCHIATRY

Quercetin, kaempferol and biapigenin fromhypericum perforatum are neuroprotective against excitotoxic insults

(2009) Bruno Silva et al.   NEUROTOXICITY RESEARCH

Targets for neuroprotection in Parkinson's disease

(2008) Talene A. Yacoubian et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Pseudohypericin is necessary for the light-activated inhibition of prostaglandin E2 pathways by a 4 component system mimicking an Hypericum perforatum fraction

(2008) Kimberly D.P. Hammer et al.   PHYTOCHEMISTRY