Repression of somatic cell fate in the germline

SOX17 Is a Critical Specifier of Human Primordial Germ Cell Fate

(2015) Naoko Irie et al.   CELL

Quantitative Dynamics of Chromatin Remodeling during Germ Cell Specification from Mouse Embryonic Stem Cells

(2015) Kazuki Kurimoto et al.   Cell Stem Cell

Transgenerational Epigenetic Inheritance: Myths and Mechanisms

(2014) Edith Heard et al.   CELL

Chromatin and Transcription Transitions of Mammalian Adult Germline Stem Cells and Spermatogenesis

(2014) Saher Sue Hammoud et al.   Cell Stem Cell

Germ-Granule Components Prevent Somatic Development in the C. elegans Germline

(2014) Dustin L. Updike et al.   CURRENT BIOLOGY

Poised chromatin in the mammalian germ line

(2014) B. J. Lesch et al.   DEVELOPMENT

The majority of early primordial germ cells acquire pluripotency by AKT activation

(2014) Y. Matsui et al.   DEVELOPMENT

Distinct chromatin organization in the germ line founder cell of theCaenorhabditis elegansembryo

(2014) Lenka Vágnerová et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

The TRIM-NHL Protein LIN-41 and the OMA RNA-Binding Proteins Antagonistically Control the Prophase-to-Metaphase Transition and Growth of Caenorhabditis elegans Oocytes

(2014) Caroline A. Spike et al.   GENETICS

Translational control in germline stem cell development

(2014) Maija Slaidina et al.   JOURNAL OF CELL BIOLOGY

Primoridal germ cell specification: a context-dependent cellular differentiation event

(2014) U. Gunesdogan et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

A Non-Cell Autonomous Role of E(z) to Prevent Germ Cells from Turning on a Somatic Cell Marker

(2014) S. H. Eun et al.   SCIENCE

H3K27me and PRC2 transmit a memory of repression across generations and during development

(2014) L. J. Gaydos et al.   SCIENCE

Sall4 Is Essential for Mouse Primordial Germ Cell Specification by Suppressing Somatic Cell Program Genes

(2014) Yasuka L. Yamaguchi et al.   STEM CELLS

Regulation of the X Chromosomes in Caenorhabditis elegans

(2014) S. Strome et al.   Cold Spring Harbor Perspectives in Biology

The SET-2/SET1 Histone H3K4 Methyltransferase Maintains Pluripotency in the Caenorhabditis elegans Germline

(2014) Valérie J. Robert et al.   Cell Reports

The TRIM-NHL Protein LIN-41 Controls the Onset of Developmental Plasticity in Caenorhabditis elegans

(2014) Cristina Tocchini et al.   PLoS Genetics

DAZL Limits Pluripotency, Differentiation, and Apoptosis in Developing Primordial Germ Cells

(2014) Hsu-Hsin Chen et al.   Stem Cell Reports

LET-418/Mi2 and SPR-5/LSD1 Cooperatively Prevent Somatic Reprogramming of C. elegans Germline Stem Cells

(2014) Stéphanie Käser-Pébernard et al.   Stem Cell Reports

Dynamics of 5-methylcytosine and 5-hydroxymethylcytosine during germ cell reprogramming

(2013) Shinpei Yamaguchi et al.   CELL RESEARCH

Phosphorylation of RNA polymerase II is independent of P-TEFb in the C. elegans germline

(2013) E. A. Bowman et al.   DEVELOPMENT

In Vivo Epigenomic Profiling of Germ Cells Reveals Germ Cell Molecular Signatures

(2013) Jia-Hui Ng et al.   DEVELOPMENTAL CELL

Prdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylation

(2013) Nils Grabole et al.   EMBO REPORTS

Induction of mouse germ-cell fate by transcription factors in vitro

(2013) Fumio Nakaki et al.   NATURE

Derivation of novel human ground state naive pluripotent stem cells

(2013) Ohad Gafni et al.   NATURE

A tripartite transcription factor network regulates primordial germ cell specification in mice

(2013) Erna Magnúsdóttir et al.   NATURE CELL BIOLOGY

Molecular determinants of nucleosome retention at CpG-rich sequences in mouse spermatozoa

(2013) Serap Erkek et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Visualization of multivalent histone modification in a single cell reveals highly concerted epigenetic changes on differentiation of embryonic stem cells

(2013) Naoko Hattori et al.   NUCLEIC ACIDS RESEARCH

A set of genes critical to development is epigenetically poised in mouse germ cells from fetal stages through completion of meiosis

(2013) B. J. Lesch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bivalent Chromatin Marks Developmental Regulatory Genes in the Mouse Embryonic Germline In Vivo

(2013) Michael Sachs et al.   Cell Reports

Xenopus Nanos1 is required to prevent endoderm gene expression and apoptosis in primordial germ cells

(2012) F. Lai et al.   DEVELOPMENT

Germ cell pluripotency, premature differentiation and susceptibility to testicular teratomas in mice

(2012) J. D. Heaney et al.   DEVELOPMENT

Cell-type-specific nuclei purification from whole animals for genome-wide expression and chromatin profiling

(2012) F. A. Steiner et al.   GENOME RESEARCH

Global profiling of DNA methylation erasure in mouse primordial germ cells

(2012) S. Guibert et al.   GENOME RESEARCH

A nuclear Argonaute promotes multigenerational epigenetic inheritance and germline immortality

(2012) Bethany A. Buckley et al.   NATURE

Amplification of siRNA in Caenorhabditis elegans generates a transgenerational sequence-targeted histone H3 lysine 9 methylation footprint

(2012) Sam Guoping Gu et al.   NATURE GENETICS

Genetics of germ cell development

(2012) Bluma J. Lesch et al.   NATURE REVIEWS GENETICS

Implication of DNA Demethylation and Bivalent Histone Modification for Selective Gene Regulation in Mouse Primordial Germ Cells

(2012) Kentaro Mochizuki et al.   PLoS One

Cyclin K goes with Cdk12 and Cdk13

(2012) Jiri Kohoutek et al.   Cell Division

Removal of Polycomb Repressive Complex 2 Makes C. elegans Germ Cells Susceptible to Direct Conversion into Specific Somatic Cell Types

(2012) Tulsi Patel et al.   Cell Reports

Antagonism between MES-4 and Polycomb Repressive Complex 2 Promotes Appropriate Gene Expression in C. elegans Germ Cells

(2012) Laura J. Gaydos et al.   Cell Reports

Maintaining Sufficient Nanos Is a Critical Function for Polar Granule Component in the Specification of Primordial Germ Cells

(2012) Girish Deshpande et al.   G3-Genes Genomes Genetics

Reconstitution of the Mouse Germ Cell Specification Pathway in Culture by Pluripotent Stem Cells

(2011) Katsuhiko Hayashi et al.   CELL

The stem cell niche: lessons from the Drosophila testis

(2011) M. de Cuevas et al.   DEVELOPMENT

Licensing of gametogenesis, dependent on RNA binding protein DAZL, as a gateway to sexual differentiation of fetal germ cells

(2011) M. E. Gill et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Caenorhabditis elegans chromatin-associated proteins SET-2 and ASH-2 are differentially required for histone H3 Lys 4 methylation in embryos and adult germ cells

(2011) Y. Xiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA Granules in Germ Cells

(2011) E. Voronina et al.   Cold Spring Harbor Perspectives in Biology

A Pre-mRNA–Associating Factor Links Endogenous siRNAs to Chromatin Regulation

(2011) Kirk B. Burkhart et al.   PLoS Genetics

Regulation of male germ cell cycle arrest and differentiation by DND1 is modulated by genetic background

(2010) M. S. Cook et al.   DEVELOPMENT

Male fetal germ cell differentiation involves complex repression of the regulatory network controlling pluripotency

(2010) Patrick S. Western et al.   FASEB JOURNAL

A spatial and temporal map of C. elegans gene expression

(2010) W. C. Spencer et al.   GENOME RESEARCH

P Granule Assembly and Function in Caenorhabditis elegans Germ Cells

(2010) D. Updike et al.   JOURNAL OF ANDROLOGY

A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity

(2010) Na-Yu Chia et al.   NATURE

Sequence-specific regulator Prdm14 safeguards mouse ESCs from entering extraembryonic endoderm fates

(2010) Ziyang Ma et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Repressive and active histone methylation mark distinct promoters in human and mouse spermatozoa

(2010) Urszula Brykczynska et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cytoplasmic Partitioning of P Granule Components Is Not Required to Specify the Germline in C. elegans

(2010) C. M. Gallo et al.   SCIENCE

Direct Conversion of C. elegans Germ Cells into Specific Neuron Types

(2010) B. Tursun et al.   SCIENCE

Trans-generational epigenetic regulation of C. elegans primordial germ cells

(2010) Hirofumi Furuhashi et al.   Epigenetics & Chromatin

Critical Function of AP-2gamma/TCFAP2C in Mouse Embryonic Germ Cell Maintenance1

(2009) Susanne Weber et al.   BIOLOGY OF REPRODUCTION

A Signaling Principle for the Specification of the Germ Cell Lineage in Mice

(2009) Yasuhide Ohinata et al.   CELL

A C. elegans LSD1 Demethylase Contributes to Germline Immortality by Reprogramming Epigenetic Memory

(2009) David J. Katz et al.   CELL

Chromatin Signatures in Multipotent Human Hematopoietic Stem Cells Indicate the Fate of Bivalent Genes during Differentiation

(2009) Kairong Cui et al.   Cell Stem Cell

The nuclear envelope—a scaffold for silencing?

(2009) Benjamin D Towbin et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Caudal-like PAL-1 directly activates the bodywall muscle module regulator hlh-1 in C. elegans to initiate the embryonic muscle gene regulatory network

(2009) H. Lei et al.   DEVELOPMENT

Conditional knockdown of Nanog induces apoptotic cell death in mouse migrating primordial germ cells

(2009) S. Yamaguchi et al.   DEVELOPMENT

Translational Repression of Cyclin E Prevents Precocious Mitosis and Embryonic Gene Activation during C. elegans Meiosis

(2009) Bjoern Biedermann et al.   DEVELOPMENTAL CELL

Elite and stochastic models for induced pluripotent stem cell generation

(2009) Shinya Yamanaka   NATURE

Direct cell reprogramming is a stochastic process amenable to acceleration

(2009) Jacob Hanna et al.   NATURE

Global Transcriptional Repression in C. elegans Germline Precursors by Regulated Sequestration of TAF-4

(2008) Tugba Guven-Ozkan et al.   CELL

AKT signaling promotes derivation of embryonic germ cells from primordial germ cells

(2008) T. Kimura et al.   DEVELOPMENT

Complex genome-wide transcription dynamics orchestrated by Blimp1 for the specification of the germ cell lineage in mice

(2008) K. Kurimoto et al.   GENES & DEVELOPMENT

Genetic Analysis of the Caenorhabditis elegans GLH Family of P-Granule Proteins

(2008) C. Spike et al.   GENETICS

Inhibition of Transcription by the Caenorhabditis elegans Germline Protein PIE-1: Genetic Evidence for Distinct Mechanisms Targeting Initiation and Elongation

(2008) Dolan Ghosh et al.   GENETICS

Drosophila Pgc protein inhibits P-TEFb recruitment to chromatin in primordial germ cells

(2008) Kazuko Hanyu-Nakamura et al.   NATURE

Chromatin dynamics during epigenetic reprogramming in the mouse germ line

(2008) Petra Hajkova et al.   NATURE

Critical function of Prdm14 for the establishment of the germ cell lineage in mice

(2008) Masashi Yamaji et al.   NATURE GENETICS