MALT1 is not alone after all: identification of novel paracaspases

Functional Characterization of Zebrafish (Danio rerio) Bcl10

(2015) Pellegrino Mazzone et al.   PLoS One

Inflammatory T Cell Responses Rely on Amino Acid Transporter ASCT2 Facilitation of Glutamine Uptake and mTORC1 Kinase Activation

(2014) Mako Nakaya et al.   IMMUNITY

Pharmacological inhibition of MALT1 protease activity protects mice in a mouse model of multiple sclerosis

(2014) Conor Mc Guire et al.   Journal of Neuroinflammation

Cleavage of roquin and regnase-1 by the paracaspase MALT1 releases their cooperatively repressed targets to promote TH17 differentiation

(2014) Katharina M Jeltsch et al.   NATURE IMMUNOLOGY

MALT1 Auto-Proteolysis Is Essential for NF-κB-Dependent Gene Transcription in Activated Lymphocytes

(2014) Mathijs Baens et al.   PLoS One

Emergence of the A20/ABIN-mediated inhibition of NF- B signaling via modifying the ubiquitinated proteins in a basal chordate

(2014) S. Yuan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

T Cell Receptor Signals to NF- B Are Transmitted by a Cytosolic p62-Bcl10-Malt1-IKK Signalosome

(2014) S. Paul et al.   Science Signaling

T Cell Receptor-Dependent Activation of mTOR Signaling in T Cells Is Mediated by Carma1 and MALT1, But Not Bcl10

(2014) K. S. Hamilton et al.   Science Signaling

Malt1-Induced Cleavage of Regnase-1 in CD4+ Helper T Cells Regulates Immune Activation

(2013) Takuya Uehata et al.   CELL

A homozygous mucosa-associated lymphoid tissue 1 (MALT1) mutation in a family with combined immunodeficiency

(2013) Haifa H. Jabara et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

A functional connection of Dictyostelium paracaspase with the contractile vacuole and a possible partner of the vacuolar proton ATPase

(2013) Entsar Saheb et al.   JOURNAL OF BIOSCIENCES

The Three CARMA Sisters: So Different, So Similar: A Portrait of the Three CARMA Proteins and Their Involvement in Human Disorders

(2013) Ivan Scudiero et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Structural Architecture of the CARMA1/Bcl10/MALT1 Signalosome: Nucleation-Induced Filamentous Assembly

(2013) Qi Qiao et al.   MOLECULAR CELL

The protease activity of the paracaspase MALT1 is controlled by monoubiquitination

(2013) Christiane Pelzer et al.   NATURE IMMUNOLOGY

Lamprey immunity is far from primitive

(2013) J. P. Rast et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New types of metacaspases in phytoplankton reveal diverse origins of cell death proteases

(2013) C J Choi et al.   Cell Death & Disease

Mechanism and specificity of the human paracaspase MALT1

(2012) Janna Hachmann et al.   BIOCHEMICAL JOURNAL

A New “Brew” of MALT1 Inhibitors

(2012) Ryan M. Young et al.   CANCER CELL

Crystal Structure of the Yeast Metacaspase Yca1

(2012) Ada Hang-Heng Wong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Two-Step Activation Mechanism of MALT1 Paracaspase

(2012) Jens Staal et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural Determinants of MALT1 Protease Activity

(2012) Christian Wiesmann et al.   JOURNAL OF MOLECULAR BIOLOGY

Prokaryotic Caspase Homologs: Phylogenetic Patterns and Functional Characteristics Reveal Considerable Diversity

(2012) Johannes Asplund-Samuelsson et al.   PLoS One

Crystal structure of a Trypanosoma brucei metacaspase

(2012) K. McLuskey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metacaspases

(2011) L Tsiatsiani et al.   CELL DEATH AND DIFFERENTIATION

T-cell receptor-induced JNK activation requires proteolytic inactivation of CYLD by MALT1

(2011) Jens Staal et al.   EMBO JOURNAL

Oligomeric Structure of the MALT1 Tandem Ig-Like Domains

(2011) Liyan Qiu et al.   PLoS One

Malt1-dependent RelB cleavage promotes canonical NF- B activation in lymphocytes and lymphoma cell lines

(2011) S. Hailfinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Crystal structure of the mucosa-associated lymphoid tissue lymphoma translocation 1 (MALT1) paracaspase region

(2011) J. W. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide comparative analysis of metacaspases in unicellular and filamentous cyanobacteria

(2010) Qiao Jiang et al.   BMC GENOMICS

Regulation of NF-κB signaling by caspases and MALT1 paracaspase

(2010) Jens Staal et al.   CELL RESEARCH

Inhibition of MALT1 protease activity is selectively toxic for activated B cell–like diffuse large B cell lymphoma cells

(2009) Uta Ferch et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Essential role of MALT1 protease activity in activated B cell-like diffuse large B-cell lymphoma

(2009) S. Hailfinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple Protein Domains Mediate Interaction between Bcl10 and MALT1

(2008) Felicia D. Langel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

T cell antigen receptor stimulation induces MALT1 paracaspase–mediated cleavage of the NF-κB inhibitor A20

(2008) Beatrice Coornaert et al.   NATURE IMMUNOLOGY

The proteolytic activity of the paracaspase MALT1 is key in T cell activation

(2008) Fabien Rebeaud et al.   NATURE IMMUNOLOGY