Effects of 12weeks of combined training without caloric restriction on inflammatory markers in overweight girls

The objective of the present study was to investigate the effects of combined training without caloric restriction on inflammatory markers in overweight girls. Thirty-three girls (13-17years) were assigned into overweight training (n=17) or overweight control (n=16) groups. Additionally, a normal-weight group (n=15) was used as control for the baseline values. The combined training programme consisted of six resistance exercises (three sets of 6-10 repetitions at 60-70% 1 RM) followed by 30min of aerobic exercise (walking/running) at 50-80% VO2peak, performed in the same 60min session, 3days/weeks, for 12weeks. Body composition, dietary intake, aerobic fitness (VO2peak), muscular strength (1 RM), glycaemia, insulinemia, lipid profile and inflammatory markers (C-reactive protein, interleukin-6, tumour necrosis factor-alpha, interleukin-10, leptin, resistin and adiponectin) were measured before and after intervention. There was a significant decrease in body fat (P<0.01) and increase in fat-free mass (P<0.01), VO2peak (P<0.01), 1 RM for leg press (P<0.01) and bench press (P<0.01) in the overweight training group. Concomitantly, this group presented significant decreases in serum concentrations of C-reactive protein (P<0.05) and leptin (P<0.05), as well as in insulin resistance (P<0.05) after the experimental period. In conclusion, 12weeks of combined training without caloric restriction reduced inflammatory markers associated with obesity in overweight girls.