Article
Psychology, Multidisciplinary
John H. Wearden
Summary: Marc Richelle made significant contributions to the study of temporal regulation of behavior in animals, with a focus on the effects of drugs on timing performance in different species. His research, particularly in collaboration with Helga Lejeune, provided valuable insights into timing competence and performance across species.
PSYCHOLOGICA BELGICA
(2021)
Article
Engineering, Biomedical
Martha G. Garcia-Garcia, Cesar Marquez-Chin, Milos R. Popovic
Summary: The study found that volitional modulation of single cortical neurons holds great potential for brain-machine interfaces, especially in acquiring novel skills. Thresholded activity tasks performed better than windowed activity tasks, showing more efficient utilization of cortical circuit adaptability.
JOURNAL OF NEURAL ENGINEERING
(2021)
Article
Anesthesiology
Frauke Nees, Beate Ditzen, Herta Flor
Summary: The study found that the processing of pain in patients with chronic pain is influenced by spouse responses, with the impact being related to whether the spouse is solicitous or nonsolicitous. When a spouse provides care and reinforcement for the pain behaviors and expressions of the patient, the processing of pain in the frontal region of the brain is significantly enhanced.
Article
Multidisciplinary Sciences
Haiyan Sun, Zhilin Li, Zhentong Qiu, Yu Shen, Qingchen Guo, Su-Wan Hu, Hai-Lei Ding, Shuming An, Jun-Li Cao
Summary: This study identifies a dual-functional neuronal ensemble in the nucleus accumbens (NAc) that regulates chronic pain and sleep. These neurons show increased activity during nociceptive stimulation or wakefulness. Activating this ensemble aggravates pain-like responses and reduces NREM sleep, while inhibiting it has the opposite effects. The results suggest a common NAc ensemble encoding chronic pain and controlling sleep through its divergent downstream circuit targets.
NATURE COMMUNICATIONS
(2023)
Article
Behavioral Sciences
Michael J. Spoelma, Robert A. Boakes
Summary: The metabolic effects of sugary drinks have been extensively studied, while less attention has been paid to their effects on psychological processes. Studies have shown that high-sugar diets can impair spatial learning and memory in rats. However, evidence supporting claims of weakened inhibitory control under high-sugar diets is limited. The present study aimed to assess the impact of high-sugar diets on response inhibition in rats, but results were inconclusive in three experiments.
Article
Clinical Neurology
Mohammad Ali Salehinejad, Anita Azarkolah, Elham Ghanavati, Michael A. Nitsche
Summary: The COVID-19 pandemic has brought extraordinary and unpredictable changes to our lifestyle, negatively affecting core aspects of wellbeing including behavior, emotion, cognition, and social interactions. Sleep difficulties and circadian misalignment are common consequences of the pandemic, requiring interventions for different populations.
Article
Psychiatry
Ciqing Bao, Yali Wang, Tao Le, Ling Xu, Weina Tang, Wanyun Zou, Yin Bao, Dongwu Xu, Ke Zhao
Summary: This study aims to explore the relationship between sleep quality and cognitive inhibition in pregnant women with depressive symptoms. Pregnant women with depressive symptoms showed worse sleep quality and cognitive inhibition compared to those without depressive symptoms. The speed of cognitive inhibition plays a mediating role in the relationship between sleep quality and prenatal depressive symptoms.
Article
Clinical Neurology
Vera Yeo, Natalie L. Phillips, Stefan Bogdanov, Naomi Brookes, Adrienne Epps, Arthur Teng, Sharon L. Naismith, Suncica Lah
Summary: The primary aim of the study was to investigate whether sleep disturbances persist in children in the chronic stage of recovery from moderate to severe traumatic brain injury (TBI), and the findings suggest that greater sleep disturbances are associated with worse functional outcomes. Further research and development of treatments are crucial in improving outcomes for children with TBI.
Article
Neurosciences
Danielle Toccalino, Catherine Wiseman-Hakes, Dora M. Zalai
Summary: The Sleep and Concussion Questionnaire (SCQ) shows convergent validity with objective sleep parameters and existing self-report measures in patients after mild traumatic brain injury (TBI).
Article
Oncology
Kelcie D. Willis, Scott G. Ravyts, Autumn Lanoye, Ashlee R. Loughan
Summary: This quality improvement project revealed a high prevalence of sleep disturbance among primary brain tumor (PBT) patients, particularly in those with higher grade tumors, significant sleep disturbance, minority racial/ethnic status, and those not already taking sleep medications. Patients showed similar interest in pharmacological and behavioral treatment.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Multidisciplinary Sciences
Tahereh Tekieh, P. A. Robinson, Svetlana Postnova
Summary: This study presents a new model that incorporates higher void volume and clearance in sleep, multiple waste compounds, and clearance obstruction by waste. The model successfully reproduces normal sleep-wake cycles, sleep deprivation effects, and performance decreases under chronic sleep restriction. The results indicate a central role for waste products with lifetimes similar to tau protein and predict tau accumulation consistent with the development of Alzheimer's disease.
SCIENTIFIC REPORTS
(2022)
Article
Behavioral Sciences
Natasha L. Hogan, Emily J. Jaehne, Sharon Bak, Elvan Djouma, Maarten van den Buuse
Summary: Impulsivity may be a potential predictor of addiction risk, while the BDNFVal66Met polymorphism may sex-specifically alter aspects of impulsive behavior and addiction propensity.
BEHAVIOURAL BRAIN RESEARCH
(2021)
Review
Clinical Neurology
Xinyi Zheng, Zheng Zhu, Juan Chen, Jiaying He, Yuhang Zhu, Lei Zhang, Fan Qu
Summary: This systematic review and meta-analysis found that cognitive behavioural therapy for insomnia (CBT-I) significantly improved sleep quality, insomnia severity, anxiety, and depression in pregnant women. The findings provide evidence for the validity of CBT-I in treating insomnia or sleep disturbances during pregnancy.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Clinical Neurology
Melanie K. Fleming, Tom Smejka, Ellie Macey, Ramon Luengo-Fernandez, Alasdair L. Henry, Barbara Robinson, Simon D. Kyle, Colin A. Espie, Heidi Johansen-Berg
Summary: This study aimed to assess the efficacy of digital cognitive behavioural therapy for insomnia to improve sleep after stroke. A parallel group randomised controlled trial was conducted remotely, and the results showed significant improvements in sleep condition for the digital cognitive behavioural therapy group compared to the control group. Cost-effectiveness analysis also found that digital cognitive behavioural therapy dominates over control. Overall, digital cognitive behavioural therapy effectively improves sleep after stroke.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Clinical Neurology
Matteo Pesoli, Rosaria Rucco, Marianna Liparoti, Anna Lardone, Giulia D'Aurizio, Roberta Minino, Emahnuel Troisi Lopez, Antonella Paccone, Carmine Granata, Giuseppe Curcio, Giuseppe Sorrentino, Laura Mandolesi, Pierpaolo Sorrentino
Summary: Sleep deprivation has a significant impact on brain connectivity and cognitive functioning, particularly affecting attentional abilities. Research findings demonstrate that 24 hours of sleep deprivation leads to major rearrangements in the brain's functional network.
NEUROLOGICAL SCIENCES
(2022)
Article
Neurosciences
Frank Raven, Youri G. Bolsius, Lara van Renssen, Elroy L. Meijer, Eddy A. van der Zee, Peter Meerlo, Robbert Havekes
Summary: Protein synthesis is crucial for long-term memory formation and consolidation, with protein synthesis inhibition selectively impairing context-fear memory consolidation at certain time points. The temporal dynamics of protein synthesis-dependent memory consolidation appear to be similar for daytime and nighttime learning.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2021)
Article
Biochemistry & Molecular Biology
Sjoerd J. van Hasselt, Maria Rusche, Alexei L. Vyssotski, Simon Verhulst, Niels C. Rattenborg, Peter Meerlo
Article
Clinical Neurology
Sjoerd J. van Hasselt, Gert-Jan Mekenkamp, Jan Komdeur, Giancarlo Allocca, Alexei L. Vyssotski, Theunis Piersma, Niels C. Rattenborg, Peter Meerlo
Summary: The study found that barnacle geese's sleep is influenced by seasonal factors, with differences in sleep patterns between winter and summer. The geese also showed different responses to sleep deprivation in the two seasons, indicating that sleep homeostasis has a certain degree of flexibility.
Review
Pharmacology & Pharmacy
Youri G. Bolsius, Matias D. Zurbriggen, Jae Kyoung Kim, Martien J. Kas, Peter Meerlo, Sara J. Aton, Robbert Havekes
Summary: Circadian clock genes serve as the molecular basis for animals' internal timekeeping, integrating temporal information into various physiological processes. In addition to their canonical cellular timekeeping functions, clock proteins interact with proteins involved in processes unrelated to timekeeping. Recent data suggests that clock genes outside the SCN play a role in fundamental brain processes and may function independently of their circadian timekeeping function under certain circumstances.
BIOCHEMICAL PHARMACOLOGY
(2021)
Article
Environmental Sciences
Sjoerd J. van Hasselt, Roelof A. Hut, Giancarlo Allocca, Alexei L. Vyssotski, Theunis Piersma, Niels C. Rattenborg, Peter Meerlo
Summary: Cloud cover can amplify the immediate effects of artificial light at night on wildlife, particularly affecting sleep during new moon nights.
ENVIRONMENTAL POLLUTION
(2021)
Article
Clinical Neurology
Youri G. Bolsius, Peter Meerlo, Martien J. Kas, Ted Abel, Robbert Havekes
Summary: Sleep deprivation can reduce the density of different types of dendritic spines in the hippocampus, with specific effects on certain branches. Specifically, sleep deprivation results in a decrease in the number of mushroom and branched spines on branch 5, while there are no significant changes on branches 1 and 2.
JOURNAL OF SLEEP RESEARCH
(2022)
Editorial Material
Neurosciences
Judith R. Homberg, Roger A. H. Adan, Natalia Alenina, Antonis Asiminas, Michael Bader, Tom Beckers, Denovan P. Begg, Arjan Blokland, Marilise E. Burger, Gertjan van Dijk, Ulrich L. M. Eisel, Ype Elgersma, Bernhard Englitz, Antonio Fernandez-Ruiz, Carlos P. Fitzsimons, Anne-Marie van Dam, Peter Gass, Joanes Grandjean, Robbert Havekes, Marloes J. A. G. Henckens, Christiane Herden, Roelof A. Hut, Wendy Jarrett, Kate Jeffrey, Daniela Jezova, Andries Kalsbeek, Maarten Kamermans, Martien J. Kas, Nael Nadif Kasri, Amanda J. Kiliaan, Sharon M. Kolk, Aniko Korosi, S. Mechiel Korte, Tamas Kozicz, Steven A. Kushner, Kirk Leech, Klaus-Peter Leech, Heidi Lesscher, Paul J. Lucassen, Anita Luthi, Liya Ma, Anne S. Mallien, Peter Meerlo, Jorge F. Mejias, Frank J. Meye, Anna S. Mitchell, Joram D. Mul, Umberto Olcese, Azahara Oliva Gonzalez, Jocelien D. A. Oliver, Massimo Pasqualetti, CyrielM. A. Pennartz, Piotr Popik, Jos Prickaerts, Liset M. de la Prida, Sidarta Ribeiro, Benn Roozendaal, Janine I. Rossato, Ali-Akbar Salari, Regien G. Schoemaker, August B. Smit, Tomonori Takeuchi, Rixt van der Veen, Marten P. Smidt, Vladyslav V. Vyazovskiy, Maximilian Wiesmann, Corette J. Wierenga, Bella Williams, Ingo Willuhn, Markus Woehr, Monique Wolvekamp, Eddy A. van der Zee, Lisa Genzel, Louk J. M. J. Vanderschuren
Summary: Policymakers are working towards promoting animal-free alternatives in scientific research and have implemented strict regulations for animal research. However, in the field of neuroscience research, it is argued that the use of animals should not be compromised until viable and translational alternatives are available and proven to be valuable.
Review
Endocrinology & Metabolism
Simone Marie Ota, Xiangpan Kong, Roelof Hut, Deborah Suchecki, Peter Meerlo
Summary: In mammals, the circadian pacemaker in the suprachiasmatic nucleus (SCN) controls daily rhythms in physiology and behavior but stress and stress hormones can shift peripheral oscillators at certain times, potentially leading to temporary adaptations or imbalances with severe consequences for health and well-being.
FRONTIERS IN NEUROENDOCRINOLOGY
(2021)
Article
Biology
Xiangpan Kong, Simone M. Ota, Deborah Suchecki, Andy Lan, Anouk I. Peereboom, Roelof A. Hut, Peter Meerlo
Summary: Uncontrollable stress can disrupt daily rhythms in physiology and behavior, affecting peripheral clocks in a time and tissue specific manner.
JOURNAL OF BIOLOGICAL RHYTHMS
(2022)
Article
Clinical Neurology
Sjoerd J. van Hasselt, Simon Verhulst, Theunis Piersma, Niels C. Rattenborg, Peter Meerlo
Summary: Intermittent sleep recording can alleviate the memory and battery capacity limitations while providing accurate sleep estimates. Correlation strength for wake and NREM sleep was higher in winter compared to summer, while correlations for REM sleep were unaffected by season. In general, increasing sample size while maintaining precision can increase statistical power.
JOURNAL OF SLEEP RESEARCH
(2022)
Article
Biology
Sjoerd J. van Hasselt, Theunis Piersma, Peter Meerlo
Summary: Sleep is a mysterious phenomenon in the animal kingdom, and its function remains a mystery. This study analyzed the correlation between accelerometry-based activity data and EEG-based sleep-wake patterns in barnacle geese. The results showed that activity scores can be used to estimate wakefulness and non-rapid eye movement sleep, but not rapid eye movement sleep and sleep architecture.
JOURNAL OF EXPERIMENTAL BIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Youri G. Bolsius, Pim R. A. Heckman, Camilla Paraciani, Sophia Wilhelm, Frank Raven, Elroy L. Meijer, Martien J. H. Kas, Steve Ramirez, Peter Meerlo, Robbert Havekes
Summary: Sleep deprivation impairs hippocampal memory processes and can cause amnesia, but it does not necessarily lead to memory loss. Instead, it results in suboptimal storage of information that cannot be retrieved without drug treatment or optogenetic stimulation.
Article
Behavioral Sciences
Xiangpan Kong, Michelle Luxwolda, Roelof A. Hut, Peter Meerlo
Summary: Stress can shift peripheral tissue clocks, such as lung and kidney, but not the central pacemaker in the suprachiasmatic nucleus. Glucocorticoids released during stress might play a crucial role in these effects. The study shows that repeated social defeat stress can shift PER2 rhythms in some tissues (lung, kidney) and not others (liver), and the mechanism of these effects varies in different tissues.
HORMONES AND BEHAVIOR
(2023)
Article
Biology
Sjoerd J. van Hasselt, Luisa Epifani, Danique Zantinge, Kornelija Vitkute, Martien J. H. Kas, Giancarlo Allocca, Peter Meerlo
Summary: In this study, the effects of low temperature on REM sleep in tree shrews were investigated. It was found that exposure to low temperature significantly suppressed REM sleep, but the loss of REM sleep was not recovered during the subsequent day and night. These findings support the high sensitivity of REM sleep to environmental temperature but do not support the homeostatic regulation of REM sleep in this species.
Article
Physiology
Sjoerd J. Van Hasselt, Massimiliano Coscia, Giancarlo Allocca, Alexei L. Vyssotski, Peter Meerlo
Summary: Sleep is an important state that is present in animals, including birds, and varies between seasons. This study found that the sleep time in birds is mainly influenced by the available dark time rather than an endogenous annual clock.
JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMS AND ENVIRONMENTAL PHYSIOLOGY
(2023)