Journal
FRONTIERS IN NUTRITION
Volume 9, Issue -, Pages -Publisher
FRONTIERS MEDIA SA
DOI: 10.3389/fnut.2022.937237
Keywords
malnutrition; congestive heart failure; contrast-associated acute kidney injury; mortality; coronary angiography (CAG)
Categories
Funding
- National Key Research and Development Program of China
- Multi-center study on key techniques for prevention, diagnosis and treatment of high risk coronary artery disease
- [2016YFC1301202]
- [DFJH2020026]
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Malnutrition is an independent risk factor for contrast-associated acute kidney injury (CA-AKI) in congestive heart failure (CHF) patients following coronary angiography (CAG).
BackgroundPrevious studies have shown that malnutrition is very common in patients with congestive heart failure (CHF) and is closely related to the occurrence of acute kidney injury. However, the relationship between malnutrition and contrast-associated acute kidney injury (CA-AKI) is unclear. Method and resultsWe obtained data from 842 patients who were diagnosed with CHF following coronary angiography (CAG) or percutaneous coronary angiography (PCI) and had follow-up information from January 2013 to February 2016. The patients were divided into 3 groups according to the Controlling Nutritional Status Score before CAG or PCI procedure (Group 1: Normal; Group 2: Mild Malnutrition; Group 3: Moderate to Severe Malnutrition). The main endpoint was CA-AKI. Univariate and multivariable logistic regression analyses were performed. 556 (60.0%) patients suffered from malnutrition before CAG or PCI. During a median follow-up of 2.1 years, A total of 49 (5.82%) patients developed CA-AKI. Additionally, 5 (1.75%), 26 (6.27%) and 18 (12.77%) events were documented in patients with normal, mild and moderate or severe malnutrition, respectively (p < 0.01). In multivariable-adjusted models, patients with malnutrition showed a significantly higher incidence of CA-AKI than those in the normal group. ConclusionMalnutrition is an independent risk factor for CA-AKI in CHF patients following CAG.
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