Pathophysiology and Clinical Meaning of Ventilation-Perfusion Mismatch in the Acute Respiratory Distress Syndrome

Inhaled Nitric Oxide Improved Refractory Hypoxemia Through Attenuation of Intra-Pulmonary Shunt

(2022) Yuxian Wang et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Effects of Prone Position on Lung Recruitment and Ventilation-Perfusion Matching in Patients With COVID-19 Acute Respiratory Distress Syndrome

(2022) Tommaso Fossali et al.   CRITICAL CARE MEDICINE

Inhaled CO2 vs. Hypercapnia Obtained by Low Tidal Volume or Instrumental Dead Space in Unilateral Pulmonary Artery Ligation: Any Difference for Lung Protection?

(2022) Elena Spinelli et al.   Frontiers in Medicine

Redistribution of Perfusion by Prone Positioning Improves Shunt in a Patient with Unilateral Lung Injury

(2022) Douglas Slobod et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Increased respiratory dead space could associate with coagulation activation and poor outcomes in COVID-19 ARDS

(2022) Jerónimo Graf et al.   JOURNAL OF CRITICAL CARE

Prone Positioning Decreases Inhomogeneity and Improves Dorsal Compliance in Invasively Ventilated Spontaneously Breathing COVID-19 Patients—A Study Using Electrical Impedance Tomography

(2022) Charalampos Pierrakos et al.   Diagnostics

Using nutrient-rich solutions and adding multiple cytoprotective agents as new strategies to develop lung preservation solutions

(2021) Lei Jing et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Addition of 5% CO2 to Inspiratory Gas Prevents Lung Injury in an Experimental Model of Pulmonary Artery Ligation

(2021) Ines Marongiu et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Potential for Lung Recruitment and Ventilation-Perfusion Mismatch in Patients With the Acute Respiratory Distress Syndrome From Coronavirus Disease 2019

(2020) Tommaso Mauri et al.   CRITICAL CARE MEDICINE

Pulmonary Angiopathy in Severe COVID-19: Physiologic, Imaging and Hematologic Observations

(2020) Brijesh V Patel et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

END-TIDAL-TO-ARTERIAL PCO2 RATIO AS SIGNIFIER FOR PHYSIOLOGIC DEAD-SPACE RATIO AND OXYGENATION DYSFUNCTION IN ACUTE RESPIRATORY DISTRESS SYNDROME

(2020) Richard H Kallet et al.   Respiratory Care

Effect of PEEP and Proning on Ventilation and Perfusion in COVID-19 ARDS

(2020) François Perier et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Validity of Empirical Estimates of the Ratio of Dead Space to Tidal Volume in ARDS

(2020) Jose Dianti et al.   Respiratory Care

Inhibition of overexpressed Kv3.4 augments HPV in endotoxemic mice

(2020) Maurizio Turzo et al.   BMC Pulmonary Medicine

Regional Lung Perfusion Analysis in Experimental ARDS by Electrical Impedance and Computed Tomography

(2020) Michael Kircher et al.   IEEE TRANSACTIONS ON MEDICAL IMAGING

Dead space ventilation promotes alveolar hypocapnia reducing surfactant secretion by altering mitochondrial function

(2019) Martina Kiefmann et al.   THORAX

Effect of Titrating Positive End-Expiratory Pressure (PEEP) With an Esophageal Pressure–Guided Strategy vs an Empirical High PEEP-Fio2 Strategy on Death and Days Free From Mechanical Ventilation Among Patients With Acute Respiratory Distress Syndrome

(2019) Jeremy R. Beitler et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Short-term Physiologic Consequences of Regional Pulmonary Vascular Occlusion in Pigs

(2019) Thomas Langer et al.   ANESTHESIOLOGY

Measurement of relative lung perfusion with electrical impedance and positron emission tomography: an experimental comparative study in pigs

(2019) T. Bluth et al.   BRITISH JOURNAL OF ANAESTHESIA

Estimated dead space fraction and the ventilatory ratio are associated with mortality in early ARDS

(2019) Luis Morales-Quinteros et al.   Annals of Intensive Care

Potential for noninvasive assessment of lung inhomogeneity using highly precise, highly time-resolved measurements of gas exchange

(2018) James E. Mountain et al.   JOURNAL OF APPLIED PHYSIOLOGY

Physiological Analysis and Clinical Performance of the Ventilatory Ratio in Acute Respiratory Distress Syndrome

(2018) Pratik Sinha et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Lung Injury Etiology and Other Factors Influencing the Relationship Between Dead-Space Fraction and Mortality in ARDS

(2017) Richard H Kallet et al.   Respiratory Care

IDH3 mediates apoptosis of alveolar epithelial cells type 2 due to mitochondrial Ca2+ uptake during hypocapnia

(2017) Martina Kiefmann et al.   Cell Death & Disease

Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries

(2016) Giacomo Bellani et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Estimating Dead-Space Fraction for Secondary Analyses of Acute Respiratory Distress Syndrome Clinical Trials

(2015) Jeremy R. Beitler et al.   CRITICAL CARE MEDICINE

Echocardiographic detection of transpulmonary bubble transit during acute respiratory distress syndrome

(2015) Florence Boissier et al.   Annals of Intensive Care

The Association Between Physiologic Dead-Space Fraction and Mortality in Subjects With ARDS Enrolled in a Prospective Multi-Center Clinical Trial

(2014) R. H. Kallet et al.   Respiratory Care

Acute Respiratory Distress Syndrome: The Prognostic Value of Ventilatory Ratio—A Simple Bedside Tool to Monitor Ventilatory Efficiency

(2013) Pratik Sinha et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Evaluation of the physiological properties of ventilatory ratio in a computational cardiopulmonary model and its clinical application in an acute respiratory distress syndrome population

(2013) P. Sinha et al.   BRITISH JOURNAL OF ANAESTHESIA

Ventilator-Induced Lung Injury

(2013) Arthur S. Slutsky et al.   NEW ENGLAND JOURNAL OF MEDICINE

Prone Positioning in Severe Acute Respiratory Distress Syndrome

(2013) Claude Guérin et al.   NEW ENGLAND JOURNAL OF MEDICINE

The ‘anatomic shunt test’ in clinical practice; contemporary description of test and in-service evaluation

(2013) Damien K Y Ming et al.   THORAX

Capnography reflects ventilation/perfusion distribution in a model of acute lung injury

(2011) G. TUSMAN et al.   ACTA ANAESTHESIOLOGICA SCANDINAVICA

Regional lung perfusion estimated by electrical impedance tomography in a piglet model of lung collapse

(2011) João Batista Borges et al.   JOURNAL OF APPLIED PHYSIOLOGY

Prevalence and prognosis of shunting across patent foramen ovale during acute respiratory distress syndrome*

(2010) Armand Mekontso Dessap et al.   CRITICAL CARE MEDICINE

Mitochondrial Ca2+ sequestration and precipitation revisited

(2010) Christos Chinopoulos et al.   FEBS Journal

Ventilatory ratio: a simple bedside measure of ventilation

(2009) P. Sinha et al.   BRITISH JOURNAL OF ANAESTHESIA

Regional CO2 tension quantitatively mediates homeostatic redistribution of ventilation following acute pulmonary thromboembolism in pigs

(2009) John Y. C. Tsang et al.   JOURNAL OF APPLIED PHYSIOLOGY

GREIT: a unified approach to 2D linear EIT reconstruction of lung images

(2009) Andy Adler et al.   PHYSIOLOGICAL MEASUREMENT

Model fitting of volumetric capnograms improves calculations of airway dead space and slope of phase III

(2009) Gerardo Tusman et al.   JOURNAL OF CLINICAL MONITORING AND COMPUTING

One-lung ventilation induces hyperperfusion and alveolar damage in the ventilated lung: an experimental study

(2008) A. Kozian et al.   BRITISH JOURNAL OF ANAESTHESIA

Positive End-Expiratory Pressure Setting in Adults With Acute Lung Injury and Acute Respiratory Distress Syndrome

(2008) Alain Mercat et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Ventilation Strategy Using Low Tidal Volumes, Recruitment Maneuvers, and High Positive End-Expiratory Pressure for Acute Lung Injury and Acute Respiratory Distress Syndrome

(2008) Maureen O. Meade et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION