Engineering probiotic-derived outer membrane vesicles as functional vaccine carriers to enhance immunity against SARS-CoV-2

Microbial cell surface engineering for high-level synthesis of bio-products

(2022) Xia Wu et al.   BIOTECHNOLOGY ADVANCES

Recombinant SARS-CoV-2 RBD with a built in T helper epitope induces strong neutralization antibody response

(2021) Qiu-dong Su et al.   VACCINE

Bacterial outer membrane vesicles and host cell death signaling

(2021) Subhash Dhital et al.   TRENDS IN MICROBIOLOGY

Bacterial Outer Membrane Vesicles: From Discovery to Applications

(2021) Mariana G. Sartorio et al.   Annual Review of Microbiology

RBD-Modified Bacterial Vesicles Elicited Potential Protective Immunity against SARS-CoV-2

(2021) Zhongqian Yang et al.   NANO LETTERS

Bacterial Outer Membrane Vesicles as a Versatile Tool in Vaccine Research and the Fight against Antimicrobial Resistance

(2021) Zhuang Zhu et al.   mBio

Recombinant Antigens Based on Non-Glycosylated Regions from RBD SARS-CoV-2 as Potential Vaccine Candidates against COVID-19

(2021) Leandro Núñez-Muñoz et al.   Vaccines

Neisseria meningitidis Factor H Binding Protein Surface Exposure on Salmonella Typhimurium GMMA Is Critical to Induce an Effective Immune Response against Both Diseases

(2021) Francesca Necchi et al.   Pathogens

Bacterial Lipoprotein Posttranslational Modifications. New Insights and Opportunities for Antibiotic and Vaccine Development

(2021) Luke Smithers et al.   Frontiers in Microbiology

Efficient markerless integration of genes in the chromosome of probiotic E. coli Nissle 1917 by bacterial conjugation

(2021) Elena M. Seco et al.   Microbial Biotechnology

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody

(2020) Dora Pinto et al.   NATURE

Site-specific glycan analysis of the SARS-CoV-2 spike

(2020) Yasunori Watanabe et al.   SCIENCE

Glycine significantly enhances bacterial membrane vesicle production: a powerful approach for isolation of LPS‐reduced membrane vesicles of probiotic Escherichia coli

(2020) Satoru Hirayama et al.   Microbial Biotechnology

Probiotic Escherichia coli Nissle 1917-derived outer membrane vesicles enhance immunomodulation and antimicrobial activity in RAW264.7 macrophages

(2020) Rujiu Hu et al.   BMC MICROBIOLOGY

Immunization with the receptor-binding domain of SARS-CoV-2 elicits antibodies cross-neutralizing SARS-CoV-2 and SARS-CoV without antibody-dependent enhancement

(2020) Jinkai Zang et al.   Cell Discovery

Post-translational targeting of a recombinant protein promotes its efficient secretion into the E. coli periplasm

(2019) A. Jimmy Ytterberg et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Bacterial outer membrane vesicles engineered with lipidated antigens as a platform for Staphylococcus aureus vaccine

(2019) Carmela Irene et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Types and origins of bacterial membrane vesicles

(2018) Masanori Toyofuku et al.   NATURE REVIEWS MICROBIOLOGY

Safe Recombinant Outer Membrane Vesicles that Display M2e Elicit Heterologous Influenza Protection

(2017) Hannah C. Watkins et al.   MOLECULAR THERAPY

Outer-membrane vesicles from Gram-negative bacteria: biogenesis and functions

(2015) Carmen Schwechheimer et al.   NATURE REVIEWS MICROBIOLOGY

Through the wall: extracellular vesicles in Gram-positive bacteria, mycobacteria and fungi

(2015) Lisa Brown et al.   NATURE REVIEWS MICROBIOLOGY

Decoration of Outer Membrane Vesicles with Multiple Antigens by Using an Autotransporter Approach

(2014) Maria H. Daleke-Schermerhorn et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Biological Functions and Biogenesis of Secreted Bacterial Outer Membrane Vesicles

(2010) Adam Kulp et al.   Annual Review of Microbiology

Lipoprotein Sorting in Bacteria

(2010) Suguru Okuda et al.   Annual Review of Microbiology

Delivery of foreign antigens by engineered outer membrane vesicle vaccines

(2010) D. J. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Recombineering: a homologous recombination-based method of genetic engineering

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