Article
Plant Sciences
Isaac Ahanamungu Makelele, Kris Verheyen, Pascal Boeckx, Landry Cizungu Ntaboba, Basile Mujinya Bazirake, Corneille Ewango, Marijn Bauters
Summary: Human disturbance is increasingly impacting tropical forest dynamics, but forests have the capacity to recover species diversity and functional diversity relatively quickly through secondary succession. However, above-ground carbon stocks only partially recover after 60 years, with a slow recovery of large trees dominating carbon stocks in old-growth forests.
JOURNAL OF VEGETATION SCIENCE
(2021)
Article
Neurosciences
Lisanne J. Van't Sant, Joshua J. White, Jan H. J. Hoeijmakers, Wilbert P. Vermeij, Dick Jaarsma
Summary: The use of EU labelling in mouse models of nervous system disorders enables visualization of transcriptional changes in different cell types, with potential introduction of non-physiological properties in labelled RNAs. Additionally, EU incorporation in highly transcriptionally-active neurons shows neurotoxic effects, suggesting implications for studying transcriptional alterations in disease models.
ACTA NEUROPATHOLOGICA COMMUNICATIONS
(2021)
Article
Biotechnology & Applied Microbiology
Reham M. Balahmar, Venkataraman Deepak, Shiva Sivasubramaniam
Summary: Cell cycle-specific cancer chemotherapy is hindered by the presence of cancer stem cells (CSC) that have the ability to self-renew. In this study, we investigated the potential of choriocarcinoma cell lines to produce spheroids and the effect of doxorubicin treatment on their invasion ability. Our findings suggest an increase in stem-cell marker expression in doxorubicin-treated spheroids and reduced invasion potential compared to non-treated spheroids.
Article
Biochemistry & Molecular Biology
Shivam Kalhan, Li Peng Evelyn Chen, Marta Garrido, Robert Hester
Summary: Reduced inhibitory control and hypersensitivity to reward are key deficits in drug dependents. This study investigates the neural processes underlying control over reward in people with a tobacco use disorder (pTUD). The findings suggest that pTUD engages different neural processes and strategies to successfully inhibit a prepotent response compared to non-smokers. Increasing preparatory control in pTUD may be a possible treatment target to enhance inhibitory control over reward.
Article
Genetics & Heredity
Anna Malekkou, Athina Theodosiou, Angelos Alexandrou, Ioannis Papaevripidou, Carolina Sismani, Edwin H. Jacobs, George J. G. Ruijter, Violetta Anastasiadou, Sofia Ourani, Emilia Athanasiou, Anthi Drousiotou, Olga Grafakou, Petros P. Petrou
Summary: Pompe disease is a rare metabolic myopathy caused by genetic variants affecting the activity of the enzyme GAA. It leads to the accumulation of undegraded glycogen in lysosomes and primarily affects muscle tissues. The severity of the disease depends on the level of residual enzymatic activity.
MOLECULAR GENETICS AND METABOLISM REPORTS
(2023)
Article
Energy & Fuels
Robert Underwood, Moonyong Kim, Storm Drury, Yuchao Zhang, Li Wang, Catherine Chan, Brett Hallam
Summary: The global cumulative PV installed capacity has exceeded 1 TW, but more PV is needed to achieve complete decarbonization. To sustainably mitigate climate change, all factors, including reducing the demand for abundant materials, must be considered.
Article
Thermodynamics
Zhiyue Han, Rongcai Zi, Yue Yu, Zhiming Du, Ling Liu, Li Deng
Summary: In this study, a liquid-phase input end is added to the cup burner to test the fire-extinguishing effect of C6F12O on lithium-ion battery syngas. The minimum extinguishing concentration (MEC) of C6F12O is determined, and the physical and chemical effects of C6F12O on lithium-ion battery syngas fire are quantified using the perfect stirred reactor (PSR) model. The results indicate that the fire-extinguishing effect of C6F12O on lithium-ion battery fire is mainly due to its physical cooling effect.
JOURNAL OF THERMAL ANALYSIS AND CALORIMETRY
(2023)
Article
Engineering, Environmental
Zhiyang Liao, Jinrong Lu, Kunting Xie, Yi Wang, Yong Yuan
Summary: Machine learning models were developed to predict the values of three photochemical reactive intermediates (PPRIs) apparent quantum yields (phi) based on dissolved organic matter (DOM) spectral parameters, experimental conditions, and calculation parameters. The CatBoost model showed the best predictive performance, outperforming traditional linear regression models. The significance of wavelength range and spectral parameters on phi PPRIs predictions was revealed, indicating that DOM with lower molecular weight, lower aromatic content, and a more autochthonous portion possessed higher phi PPRIs.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Clinical Neurology
Zheng Wang, Xinli Hu, Peng Cui, Xu Liu, Weiguo Zhu, Chao Kong, Wei Wang, Shibao Lu
Summary: The purpose of this study was to investigate the PI- and age-related cervical alignment changes of Chinese healthy population. The results showed that there was no obvious difference observed between PI and cervical sagittal parameters, except for caudal arch. However, C2-7, cranial arch, caudal arch, T1S, and C2-7 SVA increased remarkably with age. Based on the classification in the study, high or low PI apparently did not correlate with the occurrence of cervical degenerative disease.
EUROPEAN SPINE JOURNAL
(2023)
Article
Biochemistry & Molecular Biology
Yuting Zhuang, Tingting Li, Xiaoxi Hu, Yilin Xie, Xinyu Pei, Chaoqun Wang, Yuyang Li, Junwu Liu, Zhongrui Tian, Xiaowen Zhang, Lili Peng, Bo Meng, Hao Wu, Wei Yuan, Zhenwei Pan, Yanjie Lu
Summary: The long noncoding RNA (lncRNA) MetBil plays a significant role in cardiac fibrosis by interacting with METTL3 and regulating the expression of methylated fibrosis-associated genes. Overexpression of MetBil enhances collagen deposition, cardiac fibroblast proliferation, and activation, while silencing MetBil has the opposite effects. This study provides a new potential target for interventions in fibrosis-related cardiac diseases.
Article
Energy & Fuels
Hui Luo, Shilin Zhao, Anjun Ma, Kang Sun, Yanqun Zhu, Zhiqiang Sun
Summary: This study investigated the effects of flue gas components (O2, CO2, SO2, and NO) on the Hg-0 removal of mechanochemical S2Cl2-modified BC (S2Cl2-MC). It was found that O2 and CO2 promoted the escape of Hg2+ but inhibited the adsorption of Hg-0, while SO2 and NO had a certain promoting effect on the removal of Hg-0.
Article
Genetics & Heredity
Zhiqiang Xia, Lixia Xie, Dongyuan Li, Xinyi Hong, Chenhu Qin
Summary: The three members of TRPML subfamily, TRPML1, TRPML2, and TRPML3, are highly expressed in the lung tissue, as well as spleen and kidney tissues of mice. TRPML1 and TRPML3 showed decreased expression in response to LPS stimulation, while TRPML2 showed increased expression. This suggests that TRPML1 and TRPML3 play important roles in immune and inflammatory regulation.
Article
Polymer Science
Haiyan Mao, Qun Zhang, Ling Lin, Xuemei He, Lili Wang
Summary: A self-healable and recyclable zwitterionic polyurethane (ZPU) was developed by introducing ionic bonds between ammonium groups and sulfonic acid moieties. ZPU exhibits excellent thermal stability, mechanical properties, as well as self-healing and recyclable capabilities. These features make ZPU a promising material for protective coatings, stretchable substrates, and strain sensors.
Review
Environmental Sciences
Aijie Yu, Hongling Shi, Yifan Wang, Jin Yang, Chunchun Gao, Yang Lu
Summary: In recent decades, climate change has caused significant impacts on human life, such as global warming, glacier melting, extreme weather, and rising sea levels. Remote sensing technology has played a crucial role in studying and monitoring glaciers. This study analyzed 4817 literature works related to glacier mass balance based on remote sensing technology from 1990 to 2021, revealing the major countries, research institutions, hotspots, and frontiers in this field. The research findings provide valuable insights for future studies and highlight the importance of improving data quality and merging multiple methods for precise and long-term monitoring of glacier mass changes.
Article
Chemistry, Multidisciplinary
Panpan Chen, Yan Peng, Lan Lin, Yaoyao Yuan, Jie Chen, Jinling Mo, Jiayi Miao, Hongliang He, Yang Jin, Liying Zhang, Shuhu Du
Summary: In this work, a three-in-one artificial enzyme with enhanced peroxidase-like activity and outstanding stability is constructed by restricting Au-loaded CeO2 nanorods inside Cu-based metal-organic frameworks. The artificial enzyme shows significantly improved catalytic decomposition of H2O2 and strong affinities to substrates, with lower Michaelis constants than horseradish peroxidase. It also exhibits desirable stabilities in pH, temperature, organic solvents, and long-term storage. A universal colorimetric/fluorometric dual-mode sensing platform is built based on the artificial enzyme for detection of biomarkers in biological fluids. This work opens up new possibilities for designing efficient and stable biomimetic catalysts.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Article
Chemistry, Organic
Jing Yu, Xiaoyu Yan, Feng Liu, Ying Zhou, Wenxin Man, Xiantao Ma
Summary: A mild Pd-catalyzed Tsuji-Trost reaction of allylic alcohols with an amine nucleophile in water media was developed, allowing for the green synthesis of valuable allylic amines. This new method eliminates the need for chemical activators and complex soluble ligands, and can be easily scaled up to gram scale, making it applicable for the synthesis of Naftifine, a best-selling antifungal drug, showcasing the practical significance of this method.
ASIAN JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Biology
Erliang Yuan, Huijuan Guo, Weiyao Chen, Bingru Du, Yingjie Mi, Zhaorui Qi, Yiyang Yuan, Keyan Zhu-Salzman, Feng Ge, Yucheng Sun
Summary: Wing dimorphism in insects is an evolutionarily adaptive trait, with wingless individuals undergoing wing degeneration via autophagy. The TOR signaling pathway suppresses autophagy of the wing disc by negatively regulating the expression of the gene REPTOR2. Knockdown of REPTOR2 reduces autophagy and increases the proportion of winged individuals, while suppression of TOR activates autophagy and decreases the proportion of winged individuals. REPTOR2 acts as a key regulator downstream of TOR in the signaling pathway.
Article
Microbiology
Xi Wang, Yifan Wu, Yanli Liu, Feihong Chen, Sijie Chen, Feiyu Zhang, Shujin Li, Chaowei Wang, Yi Gong, Ruitian Huang, Minhan Hu, Yujie Ning, Hongmou Zhao, Xiong Guo
Summary: In this study, the gut microbiota profile in patients with knee osteoarthritis (OA) was examined using 16S rDNA gene sequencing and metagenomic sequencing. The dominant bacteria in the OA group was identified as Proteobacteria and 81 genera showed significantly different abundance between the OA and control groups. The metagenomic sequencing revealed specific species, such as Bacteroides stercoris and Escherichia coli, that were significantly altered in abundance in the OA group. These findings suggest a potential role of the cartilage-gut-microbiome axis in the mechanisms and pathogenesis of OA.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Engineering, Electrical & Electronic
Yu Zhong, Francesco Zardi, Marco Salucci, Giacomo Oliveri, Andrea Massa
Summary: In this article, a novel inversion strategy is proposed to solve inverse scattering problems with inhomogeneous backgrounds. The strategy combines the multiscaling regularization scheme and the difference contraction integral equation formulation, which mitigates nonlinearity and ill-posedness to obtain reliable high-resolution reconstructions.
IEEE TRANSACTIONS ON MICROWAVE THEORY AND TECHNIQUES
(2023)
Article
Computer Science, Information Systems
Jinchao Liang, Zijing Feng, Riqing Chen, Xiaolong Liu
Summary: A novel scheme based on basin-hopping improvement (BHI) is proposed to generate adversarial examples with invisible watermarks, achieving a high success rate of 93.5%.
INFORMATION SCIENCES
(2023)