The Molecular Signature of Human Testicular Peritubular Cells Revealed by Single-Cell Analysis

Single-cell analysis of human testis aging and correlation with elevated body mass index

(2022) Xichen Nie et al.   DEVELOPMENTAL CELL

Behavior and Functional Roles of CD34+ Mesenchymal Cells in Mammalian Testes

(2022) Shin-ichi Abe   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Single-cell analysis of the developing human testis reveals somatic niche cell specification and fetal germline stem cell establishment

(2021) Jingtao Guo et al.   Cell Stem Cell

ATP activation of peritubular cells drives testicular sperm transport

(2021) David Fleck et al.   eLife

The origin and mechanisms of smooth muscle cell development in vertebrates

(2021) Michael Donadon et al.   DEVELOPMENT

Differentiation of seminiferous tubule-associated stem cells into leydig cell and myoid cell lineages

(2021) Xingxing Zhao et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Testicular adenosine acts as a pro-inflammatory molecule: role of testicular peritubular cells

(2021) Annika Missel et al.   MOLECULAR HUMAN REPRODUCTION

Stem Leydig cells: Current research and future prospects of regenerative medicine of male reproductive health

(2021) Xiaoheng Li et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Advances in stem cell research for the treatment of primary hypogonadism

(2021) Lu Li et al.   Nature Reviews Urology

TCF21+ mesenchymal cells contribute to testis somatic cell development, homeostasis, and regeneration in mice

(2021) Yu-chi Shen et al.   Nature Communications

All trans retinoic acid alleviates coronary stenosis by regulating smooth muscle cell function in a mouse model of Kawasaki disease

(2021) Eisuke Suganuma et al.   Scientific Reports

Regulation of Gdnf expression by retinoic acid in Sertoli cells

(2020) Rossana Saracino et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Leydig‐like cells derived from reprogrammed human foreskin fibroblasts by CRISPR/dCas9 increase the level of serum testosterone in castrated male rats

(2020) Hua Huang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The Glucocorticoid Receptor NR3C1 in Testicular Peritubular Cells is Developmentally Regulated and Linked to the Smooth Muscle-Like Cellular Phenotype

(2020) Harald Welter et al.   Journal of Clinical Medicine

The myofibroblast at a glance

(2020) Pardis Pakshir et al.   JOURNAL OF CELL SCIENCE

Generalizing RNA velocity to transient cell states through dynamical modeling

(2020) Volker Bergen et al.   NATURE BIOTECHNOLOGY

A comparative analysis of human adult testicular cells expressing stem Leydig cell markers in the interstitium, vasculature, and peritubular layer

(2020) Jitske Eliveld et al.   Andrology

Endosialin defines human stem Leydig cells with regenerative potential

(2020) Kai Xia et al.   HUMAN REPRODUCTION

Age-related changes in human Leydig cell status

(2020) Valentina Mularoni et al.   HUMAN REPRODUCTION

Proteomic Insights into Senescence of Testicular Peritubular Cells from a Nonhuman Primate Model

(2020) Jan B. Stöckl et al.   Cells

The Neonatal and Adult Human Testis Defined at the Single-Cell Level

(2019) Abhishek Sohni et al.   Cell Reports

Efficient integration of heterogeneous single-cell transcriptomes using Scanorama

(2019) Brian Hie et al.   NATURE BIOTECHNOLOGY

Scrublet: Computational Identification of Cell Doublets in Single-Cell Transcriptomic Data

(2019) Samuel L. Wolock et al.   Cell Systems

Smooth Muscle Cell Phenotypic Diversity

(2019) Mingjun Liu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The roles and mechanisms of Leydig cells and myoid cells in regulating spermatogenesis

(2019) Rui Zhou et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Investigation of activin A in inflammatory responses of the testis and its role in the development of testicular fibrosis

(2019) A Christine Kauerhof et al.   HUMAN REPRODUCTION

Insights into replicative senescence of human testicular peritubular cells

(2019) Nina Schmid et al.   Scientific Reports

Retinoic Acid and Germ Cell Development in the Ovary and Testis

(2019) Tsutomu Endo et al.   Biomolecules

Prostaglandin E 2 (PGE 2 ) is a testicular peritubular cell-derived factor involved in human testicular homeostasis

(2018) Verónica Rey-Ares et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

ATP-mediated Events in Peritubular Cells Contribute to Sterile Testicular Inflammation

(2018) Lena Walenta et al.   Scientific Reports

Insights into the role of androgen receptor in human testicular peritubular cells

(2018) C. Mayer et al.   Andrology

Ca2+ Signaling and IL-8 Secretion in Human Testicular Peritubular Cells Involve the Cation Channel TRPV2

(2018) Katja Eubler et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

RNA velocity of single cells

(2018) Gioele La Manno et al.   NATURE

Reappraising the microscopic anatomy of human testis: identification of telocyte networks in the peritubular and intertubular stromal space

(2018) Mirca Marini et al.   Scientific Reports

The adult human testis transcriptional cell atlas

(2018) Jingtao Guo et al.   CELL RESEARCH

Disease-relevant transcriptional signatures identified in individual smooth muscle cells from healthy mouse vessels

(2018) Lina Dobnikar et al.   Nature Communications

Massively parallel digital transcriptional profiling of single cells

(2017) Grace X. Y. Zheng et al.   Nature Communications

Vascular Smooth Muscle Cells in Atherosclerosis

(2016) Martin R. Bennett et al.   CIRCULATION RESEARCH

Spermatogenesis: The Commitment to Meiosis

(2016) Michael D. Griswold   PHYSIOLOGICAL REVIEWS

Targeting theGdnfGene in peritubular myoid cells disrupts undifferentiated spermatogonial cell development

(2016) Liang-Yu Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq

(2016) I. Tirosh et al.   SCIENCE

Ablation of the androgen receptor from vascular smooth muscle cells demonstrates a role for testosterone in vascular calcification

(2016) Dongxing Zhu et al.   Scientific Reports

Sterile inflammation as a factor in human male infertility: Involvement of Toll like receptor 2, biglycan and peritubular cells

(2016) C. Mayer et al.   Scientific Reports

Peritubular Myoid Cells Participate in Male Mouse Spermatogonial Stem Cell Maintenance

(2014) Liang-Yu Chen et al.   ENDOCRINOLOGY

Human Testicular Peritubular Cells Host Putative Stem Leydig Cells With Steroidogenic Capacity

(2014) Luise Landreh et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Secretome Analysis of Testicular Peritubular Cells: A Window into the Human Testicular Microenvironment and the Spermatogonial Stem Cell Niche in Man

(2014) Florian Flenkenthaler et al.   JOURNAL OF PROTEOME RESEARCH

Human testicular peritubular cells: more than meets the eye

(2013) Artur Mayerhofer   REPRODUCTION

Partial loss of contractile marker proteins in human testicular peritubular cells in infertility patients

(2012) H. Welter et al.   Andrology

Mast cell tryptase stimulates production of decorin by human testicular peritubular cells: possible role of decorin in male infertility by interfering with growth factor signaling

(2011) M. Adam et al.   HUMAN REPRODUCTION

15-Deoxy-Δ12-14-Prostaglandin-J2 Induces Hypertrophy and Loss of Contractility in Human Testicular Peritubular Cells: Implications for Human Male Fertility

(2010) C. Schell et al.   ENDOCRINOLOGY

Glial cell line-derived neurotrophic factor is constitutively produced by human testicular peritubular cells and may contribute to the spermatogonial stem cell niche in man

(2010) K. Spinnler et al.   HUMAN REPRODUCTION

The myofibroblast: Paradigm for a mechanically active cell

(2009) Boris Hinz   JOURNAL OF BIOMECHANICS