Involvement of tumor suppressors PTEN and p53 in the formation of multiple subtypes of liposarcoma

Real-time polymerase chain reaction analysis of MDM2 and CDK4expression using total RNA from core-needle biopsies is useful for diagnosing adipocytic tumors

(2014) Taro Sasaki et al.   BMC CANCER

Id1-Induced IGF-II and Its Autocrine/Endocrine Promotion of Esophageal Cancer Progression and Chemoresistance--Implications for IGF-II and IGF-IR-Targeted Therapy

(2014) B. Li et al.   CLINICAL CANCER RESEARCH

The evolution of thymic lymphomas in p53 knockout mice

(2014) Crissy Dudgeon et al.   GENES & DEVELOPMENT

Novel Dedifferentiated Liposarcoma Xenograft Models Reveal PTEN Down-Regulation as a Malignant Signature and Response to PI3K Pathway Inhibition

(2013) Kathleen B. Smith et al.   AMERICAN JOURNAL OF PATHOLOGY

Decrease of apoptosis markers during adipogenic differentiation of mesenchymal stem cells from human adipose tissue

(2013) Debora Lo Furno et al.   APOPTOSIS

p53 deficiency enhances mitotic arrest and slippage induced by pharmacological inhibition of Aurora kinases

(2013) M Marxer et al.   ONCOGENE

Mdm2 controls CREB-dependent transactivation and initiation of adipocyte differentiation

(2012) P Hallenborg et al.   CELL DEATH AND DIFFERENTIATION

Regulation of Embryonic and Induced Pluripotency by Aurora Kinase-p53 Signaling

(2012) Dung-Fang Lee et al.   Cell Stem Cell

MDM2 Overexpression Deregulates the Transcriptional Control of RB/E2F Leading to DNA Methyltransferase 3A Overexpression in Lung Cancer

(2012) Y.-A. Tang et al.   CLINICAL CANCER RESEARCH

Effect of the MDM2 antagonist RG7112 on the P53 pathway in patients with MDM2-amplified, well-differentiated or dedifferentiated liposarcoma: an exploratory proof-of-mechanism study

(2012) Isabelle Ray-Coquard et al.   LANCET ONCOLOGY

Chromatin-modifying enzymes as modulators of reprogramming

(2012) Tamer T. Onder et al.   NATURE

p53-mediated heterochromatin reorganization regulates its cell fate decisions

(2012) Sathish Kumar Mungamuri et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The CDKN2A/CDKN2B/CDK4/CCND1 pathway is pivotal in well-differentiated and dedifferentiated liposarcoma oncogenesis. An analysis of 104 tumors

(2011) Caroline Louis-Brennetot et al.   GENES CHROMOSOMES & CANCER

Forming functional fat: a growing understanding of adipocyte differentiation

(2011) Ana G. Cristancho et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Aberrant AKT activation drives well-differentiated liposarcoma

(2011) A. Gutierrez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MDM2 recruitment of lysine methyltransferases regulates p53 transcriptional output

(2010) Lihong Chen et al.   EMBO JOURNAL

The Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor

(2010) J. J. Manfredi   GENES & DEVELOPMENT

FUS-CHOP Fusion Protein Expression Coupled to p53 Deficiency Induces Liposarcoma in Mouse but Not in Human Adipose-Derived Mesenchymal Stem/Stromal Cells

(2010) Rene Rodriguez et al.   STEM CELLS

Genomic profiling reveals subsets of dedifferentiated liposarcoma to follow separate molecular pathways

(2009) Ralf J. Rieker et al.   VIRCHOWS ARCHIV

A Developmental Model of Sarcomagenesis Defines a Differentiation-Based Classification for Liposarcomas

(2008) Igor Matushansky et al.   AMERICAN JOURNAL OF PATHOLOGY