Fyn-phosphorylated PIKE-A binds and inhibits AMPK signaling, blocking its tumor suppressive activity

Fyn Regulates Adipogenesis by Promoting PIKE-A/STAT5a Interaction

(2013) Margaret Chui Ling Tse et al.   MOLECULAR AND CELLULAR BIOLOGY

AMPK  Modulation in Cancer Progression: Multilayer Integrative Analysis of the Whole Transcriptome in Asian Gastric Cancer

(2012) Y. H. Kim et al.   CANCER RESEARCH

Disrupting the PIKE-A/Akt interaction inhibits glioblastoma cell survival, migration, invasion and colony formation

(2012) Q Qi et al.   ONCOGENE

The association of phosphoinositide 3-kinase enhancer A with hepatic insulin receptor enhances its kinase activity

(2011) Chi Bun Chan et al.   EMBO REPORTS

Up-regulation of AMP-activated Protein Kinase in Cancer Cell Lines Is Mediated through c-Src Activation

(2011) Sarit Mizrachy-Schwartz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The tumor suppressor kinase LKB1: lessons from mouse models

(2011) S. Ollila et al.   Journal of Molecular Cell Biology

Fyn-Dependent Regulation of Energy Expenditure and Body Weight Is Mediated by Tyrosine Phosphorylation of LKB1

(2010) Eijiro Yamada et al.   Cell Metabolism

Deficiency of Phosphoinositide 3-Kinase Enhancer Protects Mice From Diet-Induced Obesity and Insulin Resistance

(2010) C. B. Chan et al.   DIABETES

AMPK as a metabolic tumor suppressor: control of metabolism and cell growth

(2010) Zhijun Luo et al.   Future Oncology

Automated Network Analysis Identifies Core Pathways in Glioblastoma

(2010) Ethan Cerami et al.   PLoS One

AMPK-dependent hormonal regulation of whole-body energy metabolism

(2009) N. L. Dzamko et al.   Acta Physiologica

Development of protein kinase activators: AMPK as a target in metabolic disorders and cancer

(2009) S. Fogarty et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

GGAP2/PIKE-A Directly Activates Both the Akt and Nuclear Factor- B Pathways and Promotes Prostate Cancer Progression

(2009) Y. Cai et al.   CANCER RESEARCH

LKB1 and AMPK Family Signaling: The Intimate Link Between Cell Polarity and Energy Metabolism

(2009) Marnix Jansen et al.   PHYSIOLOGICAL REVIEWS

An E2F1-Dependent Gene Expression Program that Determines the Balance between Proliferation and Cell Death

(2008) Timothy C. Hallstrom et al.   CANCER CELL

Downregulation of AMP-activated protein kinase by Cidea-mediated ubiquitination and degradation in brown adipose tissue

(2008) Jingzong Qi et al.   EMBO JOURNAL

Netrin-1 mediates neuronal survival through PIKE-L interaction with the dependence receptor UNC5B

(2008) Xiaoling Tang et al.   NATURE CELL BIOLOGY