Pharmacological targeting of guanosine monophosphate synthase suppresses melanoma cell invasion and tumorigenicity

Pathways and therapeutic targets in melanoma

(2015) Emma Shtivelman et al.   Oncotarget

Cancer treatment and survivorship statistics, 2014

(2014) Carol E. DeSantis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Cancer statistics, 2014

(2014) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Direct role of nucleotide metabolism in C-MYC-dependent proliferation of melanoma cells

(2014) Sudha Mannava et al.   CELL CYCLE

Nucleotide Biosynthetic Enzyme GMP Synthase Is a TRIM21-Controlled Relay of p53 Stabilization

(2014) B. Ashok Reddy et al.   MOLECULAR CELL

FAK competes for Src to promote migration against invasion in melanoma cells

(2014) K Kolli-Bouhafs et al.   Cell Death & Disease

Treating advanced melanoma: current insights and opportunities

(2014) Michael Tronnier et al.   Cancer Management and Research

Expression of kinA and kinB of Bacillus subtilis, Necessary for Sporulation Initiation, Is under Positive Stringent Transcription Control

(2013) S. Tojo et al.   JOURNAL OF BACTERIOLOGY

A novel role for the anti-senescence factor TBX2 in DNA repair and cisplatin resistance

(2013) S Wansleben et al.   Cell Death & Disease

The role of thioredoxin 1 in the mycophenolic acid-induced apoptosis of insulin-producing cells

(2013) K H Huh et al.   Cell Death & Disease

FK506 binding protein 51 positively regulates melanoma stemness and metastatic potential

(2013) S Romano et al.   Cell Death & Disease

AEBP1 upregulation confers acquired resistance to BRAF (V600E) inhibition in melanoma

(2013) W Hu et al.   Cell Death & Disease

Development of a human three-dimensional organotypic skin-melanoma spheroid model for in vitro drug testing

(2013) H Vörsmann et al.   Cell Death & Disease

Contribution of serine, folate and glycine metabolism to the ATP, NADPH and purine requirements of cancer cells

(2013) P M Tedeschi et al.   Cell Death & Disease

A Purine Nucleotide Biosynthesis Enzyme Guanosine Monophosphate Reductase Is a Suppressor of Melanoma Invasion

(2013) Joseph A. Wawrzyniak et al.   Cell Reports

Depletion of Deoxyribonucleotide Pools Is an Endogenous Source of DNA Damage in Cells Undergoing Oncogene-Induced Senescence

(2012) Sudha Mannava et al.   AMERICAN JOURNAL OF PATHOLOGY

Links between metabolism and cancer

(2012) C. V. Dang   GENES & DEVELOPMENT

A preclinical and clinical study of mycophenolate mofetil in pancreatic cancer

(2012) J. Rodríguez-Pascual et al.   INVESTIGATIONAL NEW DRUGS

Mechanism of USP7/HAUSP Activation by Its C-Terminal Ubiquitin-like Domain and Allosteric Regulation by GMP-Synthetase

(2011) Alex C. Faesen et al.   MOLECULAR CELL

PP2A-B56α controls oncogene-induced senescence in normal and tumor human melanocytic cells

(2011) S Mannava et al.   ONCOGENE

Proton pump inhibition induces autophagy as a survival mechanism following oxidative stress in human melanoma cells

(2010) M L Marino et al.   Cell Death & Disease

The molecular determinants of de novo nucleotide biosynthesis in cancer cells

(2009) Xuemei Tong et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Biosynthetic Enzyme GMP Synthetase Cooperates with Ubiquitin-Specific Protease 7 in Transcriptional Regulation of Ecdysteroid Target Genes

(2009) J. A. van der Knaap et al.   MOLECULAR AND CELLULAR BIOLOGY

Molecular mechanisms of the antiangiogenic and antitumor effects of mycophenolic acid

(2008) Sophie Domhan et al.   MOLECULAR CANCER THERAPEUTICS

Global Regulation of Nucleotide Biosynthetic Genes by c-Myc

(2008) Yen-Chun Liu et al.   PLoS One