Short-term outcomes after simultaneous gastrectomy plus cholecystectomy in gastric cancer: A pooling up analysis

The purpose of this study was to evaluate the short-term outcomes after simultaneous gastrectomy plus cholecystectomy in gastric cancer patients. PUBMED, EMBASE, and the Cochrane Library were searched from inception to Apr 15, 2021. Short-term surgical outcomes were compared between the simultaneous gastrectomy plus cholecystectomy group and the gastrectomy only group. Five retrospective studies with 3,315 patients and 1 randomized controlled trial with 130 patients were included. There was no significant difference in age, sex, surgical methods, or reconstruction. In terms of short-term outcomes, no significance was found in postoperative complications (odds ratio, OR = 1.08, I (2) = 24%, 95% CI = 0.78-1.50, P = 0.65), postoperative biliary complications (OR = 0.98, I (2) = 0%, 95% CI = 0.43-2.25, P = 0.96), mortality (OR = 1.28, I (2) = 0%, 95% CI = 0.49-3.37, P = 0.61), and postoperative hospital stay (MD = -0.10, I (2) = 0%, 95% CI = -0.73-0.54, P = 0.77) between the two groups. Simultaneous gastrectomy plus cholecystectomy in gastric cancer patients is safe and does not increase the short-term outcomes.

Automated summary

The purpose of this study was to evaluate the short-term outcomes of simultaneous gastrectomy plus cholecystectomy in gastric cancer patients. The study included 5 retrospective studies and 1 randomized controlled trial, with a total of 3,315 patients. The results showed that there were no significant differences in short-term outcomes between the simultaneous gastrectomy plus cholecystectomy group and the gastrectomy only group in terms of postoperative complications, biliary complications, mortality, and postoperative hospital stay. Therefore, simultaneous gastrectomy plus cholecystectomy is safe and does not increase short-term outcomes in gastric cancer patients.