Pontin, a new mutant p53-binding protein, promotes gain-of-function of mutant p53

LIF promotes tumorigenesis and metastasis of breast cancer through the AKT-mTOR pathway

(2015) Xiaoyan Li et al.   Oncotarget

Glutaminase 2 negatively regulates the PI3K/AKT signaling and shows tumor suppression activity in human hepatocellular carcinoma

(2015) Juan Liu et al.   Oncotarget

ITPR1 Protects Renal Cancer Cells against Natural Killer Cells by Inducing Autophagy

(2014) Y. Messai et al.   CANCER RESEARCH

Tumour-suppressivemicroRNA-224inhibits cancer cell migration and invasion via targeting oncogenicTPD52in prostate cancer

(2014) Yusuke Goto et al.   FEBS LETTERS

LIF negatively regulates tumour-suppressor p53 through Stat3/ID1/MDM2 in colorectal cancers

(2014) Haiyang Yu et al.   Nature Communications

Mutant p53 Prolongs NF-κB Activation and Promotes Chronic Inflammation and Inflammation-Associated Colorectal Cancer

(2013) Tomer Cooks et al.   CANCER CELL

TNRC9 Downregulates BRCA1 Expression and Promotes Breast Cancer Aggressiveness

(2013) J. Shan et al.   CANCER RESEARCH

Gain-of-function mutant p53 downregulates miR-223 contributing to chemoresistance of cultured tumor cells

(2013) S Masciarelli et al.   ONCOGENE

RNAi-mediated stathmin suppression reduces lung metastasis in an orthotopic neuroblastoma mouse model

(2013) F L Byrne et al.   ONCOGENE

EGF receptor trafficking: consequences for signaling and cancer

(2013) Alejandra Tomas et al.   TRENDS IN CELL BIOLOGY

First identification of small-molecule inhibitors of Pontin by combining virtual screening and enzymatic assay

(2012) Judith Elkaim et al.   BIOCHEMICAL JOURNAL

Mutant p53 Disrupts Mammary Tissue Architecture via the Mevalonate Pathway

(2012) William A. Freed-Pastor et al.   CELL

Mutant p53: one name, many proteins

(2012) W. A. Freed-Pastor et al.   GENES & DEVELOPMENT

Identification and validation of new autoantibodies for the diagnosis of DCIS and node negative early-stage breast cancers

(2012) Jérôme Lacombe et al.   INTERNATIONAL JOURNAL OF CANCER

p53 mutations in cancer

(2012) Patricia A. J. Muller et al.   NATURE CELL BIOLOGY

A Pin1/Mutant p53 Axis Promotes Aggressiveness in Breast Cancer

(2011) Javier E. Girardini et al.   CANCER CELL

A member of the ETS family, EHF, and the ATPase RUVBL1 inhibit p53-mediated apoptosis

(2011) Kenzui Taniue et al.   EMBO REPORTS

Annexin-1 interacts with NEMO and RIP1 to constitutively activate IKK complex and NF-κB: implication in breast cancer metastasis

(2011) P Bist et al.   ONCOGENE

Modulation of the Vitamin D3 Response by Cancer-Associated Mutant p53

(2010) Perry Stambolsky et al.   CANCER CELL

Negative Regulation of Tumor Suppressor p53 by MicroRNA miR-504

(2010) Wenwei Hu et al.   MOLECULAR CELL

The regulation of energy metabolism and the IGF-1/mTOR pathways by the p53 protein

(2010) Zhaohui Feng et al.   TRENDS IN CELL BIOLOGY

Regulation of gap-junction protein connexin 43 by β-adrenergic receptor stimulation in rat cardiomyocytes

(2009) Yi Xia et al.   ACTA PHARMACOLOGICA SINICA

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

(2009) Balazs Györffy et al.   BREAST CANCER RESEARCH AND TREATMENT

Promyelocytic Leukemia Protein is Required for Gain of Function by Mutant p53

(2009) S. Haupt et al.   CANCER RESEARCH

Gap Junctions and Cancer: New Functions for an Old Story

(2008) Laurent Cronier et al.   ANTIOXIDANTS & REDOX SIGNALING

p19Arf Inhibits the Invasion of Hepatocellular Carcinoma Cells by Binding to C-terminal Binding Protein

(2008) Y.-W. Chen et al.   CANCER RESEARCH

Identification of ATPases Pontin and Reptin as Telomerase Components Essential for Holoenzyme Assembly

(2008) Andrew S. Venteicher et al.   CELL

Human Rvb1/Tip49 Is Required for the Histone Acetyltransferase Activity of Tip60/NuA4 and for the Downregulation of Phosphorylation on H2AX after DNA Damage

(2008) S. Jha et al.   MOLECULAR AND CELLULAR BIOLOGY

Chaperone-dependent stabilization and degradation of p53 mutants

(2008) P Muller et al.   ONCOGENE