Nesprin-2-dependent ERK1/2 compartmentalisation regulates the DNA damage response in vascular smooth muscle cell ageing

The Tumor Suppressor PML Specifically Accumulates at RPA/Rad51-Containing DNA Damage Repair Foci but Is Nonessential for DNA Damage-Induced Fibroblast Senescence

(2014) S. Munch et al.   MOLECULAR AND CELLULAR BIOLOGY

Mechanisms controlling the smooth muscle cell death in progeria via down-regulation of poly(ADP-ribose) polymerase 1

(2014) H. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of differential protein interactors of lamin A and progerin

(2014) Nard Kubben et al.   Nucleus

Prelamin A Accelerates Vascular Calcification Via Activation of the DNA Damage Response and Senescence-Associated Secretory Phenotype in Vascular Smooth Muscle Cells

(2013) Yiwen Liu et al.   CIRCULATION RESEARCH

A-Type Lamins Maintain the Positional Stability of DNA Damage Repair Foci in Mammalian Nuclei

(2013) Robert Mahen et al.   PLoS One

Large-Scale Modelling of the Divergent Spectrin Repeats in Nesprins: Giant Modular Proteins

(2013) Flavia Autore et al.   PLoS One

Mutations in LMNA Modulate the Lamin A - Nesprin-2 Interaction and Cause LINC Complex Alterations

(2013) Liu Yang et al.   PLoS One

Trajectories and nuclear arrangement of PML bodies are influenced by A-type lamin deficiency

(2012) Lenka Stixová et al.   BIOLOGY OF THE CELL

The nuclear lamins: flexibility in function

(2012) Brian Burke et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

BMK1 is involved in the regulation of p53 through disrupting the PML–MDM2 interaction

(2012) Q Yang et al.   ONCOGENE

Multiple Novel Nesprin-1 and Nesprin-2 Variants Act as Versatile Tissue-Specific Intracellular Scaffolds

(2012) Dipen Rajgor et al.   PLoS One

Role of DNA damage in atherosclerosis—Bystander or participant?

(2011) Kelly Gray et al.   BIOCHEMICAL PHARMACOLOGY

Recapitulation of premature ageing with iPSCs from Hutchinson–Gilford progeria syndrome

(2011) Guang-Hui Liu et al.   NATURE

Histone H4 lysine 16 hypoacetylation is associated with defective DNA repair and premature senescence in Zmpste24-deficient mice

(2011) V. Krishnan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stabilization of the Spectrin-Like Domains of Nesprin-1α by the Evolutionarily Conserved “Adaptive” Domain

(2010) Zhixia Zhong et al.   Cellular and Molecular Bioengineering

Both ERK1 and ERK2 kinases promote G2/M arrest in etoposide-treated MCF7 cells by facilitating ATM activation

(2010) Fengxiang Wei et al.   CELLULAR SIGNALLING

Prelamin A Acts to Accelerate Smooth Muscle Cell Senescence and Is a Novel Biomarker of Human Vascular Aging

(2010) Cassandra D. Ragnauth et al.   CIRCULATION

Novel Nuclear Nesprin-2 Variants Tether Active Extracellular Signal-regulated MAPK1 and MAPK2 at Promyelocytic Leukemia Protein Nuclear Bodies and Act to Regulate Smooth Muscle Cell Proliferation

(2009) Derek T. Warren et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Signaling dynamics of the KSR1 scaffold complex

(2009) M. M. McKay et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fast regulation of AP-1 activity through interaction of lamin A/C, ERK1/2, and c-Fos at the nuclear envelope

(2008) José María González et al.   JOURNAL OF CELL BIOLOGY