Article
Clinical Neurology
Tathiana Correa Rangel, Maria Cristina Falcao Raposo, Pedro Augusto Sampaio Rocha-Filho
Summary: There is a possible association between migraine, anxiety, and depression with insomnia in university students, but not with tension-type headache. The severity of insomnia is positively correlated with the impact and frequency of headaches.
Review
Clinical Neurology
Lars Jacob Stovner, Knut Hagen, Mattias Linde, Timothy J. Steiner
Summary: This article summarizes the epidemiological studies of headache disorders globally, finding that headache disorders remain highly prevalent worldwide, and identifies methodological factors explaining the large variation between study findings. While migraine prevalence estimates increased over time, estimates for all headache types varied between world regions.
JOURNAL OF HEADACHE AND PAIN
(2022)
Review
Oncology
Carolyn A. Bernstein
Summary: This review article provides a comprehensive overview of headache evaluation and treatment in cancer patients, including the diagnostic process, common types of headaches, pharmacological treatment, and complementary and integrative therapies.
Article
Medicine, General & Internal
Iwona Rosciszewska-Zukowska, Sabina Galiniak, Halina Bartosik-Psujek
Summary: The aim of this study was to assess the prevalence and characteristics of headaches in Multiple Sclerosis (MS) patients treated with disease-modifying therapies (DMTs). The study found that more than half of MS patients experienced headaches, with the prevalence of migraines being almost three times higher than tension-type headaches. Migraines in MS patients had high severity and typical migraine characteristics.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Clinical Neurology
Theodoros S. Constantinidis, Chryssa Arvaniti, Nikolaos Fakas, Jobst Rudolf, Evangelos Kouremenos, Ermioni Giannouli, Dimos D. Mitsikostas
Summary: This study estimated the prevalence, burden, and treatment of disabling primary headaches in a large sample of the Greek population aged 18-70 years old. The results showed that more than 10% of Greek adults experience disabling headaches, with over 80% never having taken pharmacological prophylaxis and a preference for oral medication for treatment.
Article
Clinical Neurology
Theodoros Constantinidis, Chryssa Arvaniti, Nikolaos Fakas, Jobst Rudolf, Evangelos Kouremenos, Ermioni D. Giannouli, Dimos Mitsikostas, Hellenic Headache Society
Summary: This study aimed to estimate the prevalence and burden of medication overuse headache in a representative sample of the Greek population. Results showed that the prevalence of medication overuse headache in Greece was 0.7%, with a higher proportion in females. The impact on work performance and productivity was significant. Medication overuse headache is a serious socio-economic health problem that requires immediate health policy planning.
Article
Clinical Neurology
Zhao Dong, Kaiming Liu, Huanxian Liu, Zhihua Jia, Wei Gui, Ming Dong, Yingying Cheng, Yudan Lv, Kang Qu, Hongru Zhao, Jianjun Chen, Dan Zhang, Zhiliang Fan, Xiaosu Yang, Dongmei Hu, Yanbo Zhang, Hongyan Xie, Mingxin Li, Bing Wen, Sufen Chen, Peng Xu, Qingqing Rong, Qiu He, Zhanxiu Ren, Fanhong Yan, Heling Zhao, Min Chen, Tingmin Yu, Hongli Qu, Xingkai An, Huailian Guo, Xinhua Zhang, Xiaoping Pan, Xiaojuan Wang, Shi Qiu, Lvming Zhang, Hongling Zhao, Xin Pan, Qi Wan, Lanyun Yan, Jing Liu, Zhe Yu, Mingjie Zhang, Ye Ran, Xun Han, Shengyuan Yu
Summary: This study aimed to investigate the prevalence and clinical features of fibromyalgia in Chinese hospital patients with primary headache. The results showed that the prevalence of fibromyalgia in Chinese patients with primary headache was 6.0%, and it was more common in patients with chronic headache. The most common sites of fibromyalgia pain were the neck, shoulders, and back.
Review
Anesthesiology
Heejin Lee, Saeyoon Kim, Min Cheol Chang
Summary: According to this study, migraine in children and adolescents is more associated with depression, while tension-type headache (TTH) is more associated with anxiety. Therefore, it is important to consider psychological symptoms in the diagnosis and treatment of primary headache disorders.
Article
Medicine, Research & Experimental
Katharina Schiller, Markus Rauchenzauner, Tamir Avidgor, Sana Hannan, Carlo Lorenzen, Manuela Kaml, Gerald Walser, Iris Unterberger, Vera Filippi, Gregor Broessner, Gerhard Luef
Summary: This study examined the distribution of different primary headache disorders in a large cohort of patients with diagnosed epilepsy. The most common headache types in epilepsy patients were migraine and tension-type headache. Female epilepsy patients reported headaches significantly more often than male patients. Monotherapy in antiepileptic drugs (AEDs) might have a beneficial effect on the frequency of headache compared to polytherapy.
EUROPEAN JOURNAL OF MEDICAL RESEARCH
(2023)
Review
Chemistry, Multidisciplinary
Aida Herranz-Gomez, Irene Garcia-Pascual, Pablo Montero-Iniesta, Roy La Touche, Alba Paris-Alemany
Summary: Manual therapy and aerobic exercise have significant intervention effects on pain intensity and quality of life in patients with migraines, tension-type headaches, and cervicogenic headaches, while the effects on pain frequency and disability vary.
APPLIED SCIENCES-BASEL
(2021)
Article
Biochemistry & Molecular Biology
Maram H. Alshareef, Bayan Hashim Alsharif
Summary: This study investigated the prevalence of primary headache disorders and associated risk factors in Makkah. The results showed a high prevalence of headaches, particularly among young adults. Age, chronic diseases, work, caffeine consumption, and smoking were found to be associated with headaches. The prevalence of headaches in Makkah has increased compared to previous studies.
Article
Clinical Neurology
Inna E. Tchivileva, Richard Ohrbach, Roger B. Fillingim, Feng-Chang Lin, Pei Feng Lim, Samuel J. Arbes, Gary D. Slade
Summary: Headache attributed to Temporomandibular Disorder (HATMD) is a common secondary headache among patients with chronic myogenous TMD and primary headaches, often presenting as migraine. Unlike primary headaches, HATMD is associated with higher headache frequency and examination-evoked masticatory muscle pain, but surprisingly few measures of facial pain, general health, and psychological distress. Understanding these differences is important for developing targeted strategies for HATMD management.
JOURNAL OF HEADACHE AND PAIN
(2021)
Article
Medicine, General & Internal
Chenghui Pi, Yinglu Liu, Lingling Li, Wenjing Tang, Xin Yan, Shengyuan Yu
Summary: This systematic review and meta-analysis examined the effects of non-pharmacological treatments on acute headaches in patients with episodic migraine and tension-type headache. The results showed that neuromodulation, acupuncture, and aerobic exercises were associated with reduced headache symptoms. However, further high-quality studies are needed for more detailed conclusions.
Review
Orthopedics
Mohammadreza Pourahmadi, Jan Dommerholt, Cesar Fernandez-de-Las-Penas, Bart Willem Koes, Mohammad Ali Mohseni-Bandpei, Mohammad Ali Mansournia, Somayeh Delavari, Abbasali Keshtkar, Mehrdad Bahramian
Summary: Dry needling does not show significant advantages in short-term relief of headache pain intensity for patients with TTH and CGH, but is more effective in improving related disabilities. Further high-quality studies are needed.
Article
Clinical Neurology
Laura Rapisarda, Michele Trimboli, Francesco Fortunato, Antonio De Martino, Oreste Marsico, Giulio Demonte, Antonio Augimeri, Angelo Labate, Antonio Gambardella
Summary: The study examined headache variations related to intensive facemask usage among healthcare professionals in Italy, with some previously headache-free individuals developing de novo headaches and existing primary headache disorders exacerbating, especially for those with migraine.
NEUROLOGICAL SCIENCES
(2021)
Article
Genetics & Heredity
Kuljeet Singh, Sachin Kumar, Sourabh Shastri, Amrit Sudershan, Vibhakar Mansotra
Summary: The catastrophic phase of Covid-19 has led to the emergence of a myriad of complications and manifestations associated with mucormycosis fungal infection. In India, 102 cases of mucormycosis linked to Covid-19 have been reported, predominantly affecting male patients and active Covid-19 cases.
Article
Multidisciplinary Sciences
Amrit Sudershan, Kanak Mahajan, Rakesh K. Panjaliya, Manoj K. Dhar, Parvinder Kumar
Summary: Sampling methods for studying population behavior are uncertain and require representative samples for generalization. Sample size greatly affects the detection of research effects, with smaller samples having lower statistical power and higher risk of missing underlying differences. This study provides a calculation method for determining sample availability during research.
SCIENTIFIC REPORTS
(2022)
Review
Clinical Neurology
Amrit Sudershan, Mohd Younis, Srishty Sudershan, Parvinder Kumar
Summary: This article reviews the various aspects of microglial activation signaling pathways to elucidate the correlation between microglial involvement and the progression of migraine conditions.
NEUROLOGICAL RESEARCH
(2023)
Article
Clinical Neurology
Sawan Kumar, Jyotdeep Kour Raina, Amrit Sudershan, Kanak Mahajan, Raman Jasrotia, Chinmoyee Maharana, Rakesh K. K. Panjalia, Parvinder Kumar
Summary: This study focuses on the association of ESR1 gene polymorphisms (PvuII and XbaI) with migraine. The results show a significant association between ESR-XbaI polymorphism and migraine, including both subtypes: migraine with aura and migraine without aura. This study highlights the importance of multiple environmental and genetic factors in understanding the complexity of migraine.
EUROPEAN NEUROLOGY
(2023)
Article
Clinical Neurology
Amrit Sudershan, Srishty Sudershan, Mohd Younis, Meenakshi Bhagat, Agar Chander Pushap, Hardeep Kumar, Parvinder Kumar
Summary: This meta-analysis found that the TNF-alpha 308G > A mutation is associated with an increased risk of migraine only in the Asian population.
Article
Biochemistry & Molecular Biology
Amrit Sudershan, Agar Chander Pushap, Hardeep Kumar, Parvinder Kumar
Summary: The present meta-analysis found that MTHFR-C677T is significantly associated with an increased risk of migraine and its clinical subtype. ACE I/D also significantly increases the risk of overall migraine and both clinical subtypes. MTHFR A1289C only increases the risk of migraine in certain genetic models.
JOURNAL OF MOLECULAR NEUROSCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Amrit Sudershan, Meenakshi Bhagat, Kuljeet Singh, Agar Chander Pushap, Hardeep Kumar, Parvinder Kumar
Summary: Migraine is a complex neurovascular disorder with multiple genes influencing pain threshold susceptibility. This meta-analysis aimed to investigate the association between eNOS gene variants and the risk of migraine and its clinical subtypes. The results showed a significant protective association between rs743506 and migraine, while rs1799983 and rs3918226 were found to be significantly associated with the risk of migraine with aura. Further studies are needed to establish the risk.
JOURNAL OF MOLECULAR NEUROSCIENCE
(2023)
Article
Cell Biology
Meenakshi Bhagat, Jyotdeep Kour Raina, Minakashee Sharma, Amrit Sudershan, Kanak Mahajan, Isha Sharma, Rakesh K. Panjalia, Parvinder Kumar
Summary: This study examines the association between genetic polymorphisms (ACE I/D, eNOS 4a/b, MTHFR rs1801133, and CYP11B2 T344C) and chronic kidney diseases (CKD) in the population of Jammu region. The results show a significant correlation between these genetic variations and the risk of CKD.
Article
Cell Biology
Sushma Devi, Jyotdeep Kour Raina, Pawan Kumar, Amrit Sudershan, Ravi Sharma, Rakesh K. Panjalyia, Sanjeev K. Digra, Parvinder Kumar
Summary: This study investigated the frequency and association of specific genetic variations with the risk of leukemia in the Jammu region of north Indian population. The results showed that rs1801133 of MTHFR, rs4646903 of CYP1A1, and GSTT1-null mutation were significantly associated with leukemia risk.