4.6 Article

Neuroepidemiology study of headache in the region of Jammu of north Indian population: A cross-sectional study

Journal

FRONTIERS IN NEUROLOGY
Volume 13, Issue -, Pages -

Publisher

FRONTIERS MEDIA SA
DOI: 10.3389/fneur.2022.1030940

Keywords

headache; prevalence; Jammu; north India; migraine; tension type headache

Ask authors/readers for more resources

This study investigated the prevalence of headache and its two major types (migraine and tension-type headache) in the Jammu Division of north India. The results showed that the overall prevalence of headache was 53.84%, with migraine being more prevalent than tension-type headache. More females were affected, and female migraine sufferers had the highest prevalence.
BackgroundHeadache disorders now represent a major public health problem globally. It is more prevalent in developing countries with the rising trends of headache disorders observed in young adults affecting their quality of life negatively. Very little information is available on the epidemiology of headache disorders in the Jammu Division of the north Indian population. AimThe aim of the present study was to find out the prevalence of headache and its two major types, i.e., migraine and tension-type headache (TTH), in the population of the Jammu Division. MethodsThe present study was conducted in two phases: (Phase I: face-to-face interview and Phase II: E-based sampling) and the sufferers of headaches were incorporated into the study based on the International Classification of Headache Disorder-3 (ICHD-3) criteria for a representative sample. Frequency distribution and mean +/- standard deviation were used in descriptive statistics to describe the data sets, while a t-test, chi-square test, multiple logistic regression, and prevalence ratio were used in inferential statistics. ResultsIn the present study, a total of 3,148 patients were recruited, with an overall prevalence of headache of 53.84%, with a majority of females (38.18%) over males (15.66%). As regards the type of headache, migraine was found to be of the more prevalent (33.25%) type than the TTH (20.58%). Females suffering from migraine showed the highest prevalence (25.28%), in contrast to females suffering from the TTH (12.89%). Sociodemographic variables, such as gender [female; AOR = 2.46, 95% CI (2.12-2.85), p-value < 0.0001] and marital status [married; AOR: 1.46, 95% CI (1.11-1.92) p-value = 0.006], showed a significant association with the headache. ConclusionThe present study shows that the prevalence of headache is high in the Jammu Division of Jammu and Kashmir (J&K) India, with migraine being the highly prevalent type.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.6
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

Article Genetics & Heredity

Black fungus immunosuppressive epidemic with Covid-19 associated mucormycosis (zygomycosis): a clinical and diagnostic perspective from India

Kuljeet Singh, Sachin Kumar, Sourabh Shastri, Amrit Sudershan, Vibhakar Mansotra

Summary: The catastrophic phase of Covid-19 has led to the emergence of a myriad of complications and manifestations associated with mucormycosis fungal infection. In India, 102 cases of mucormycosis linked to Covid-19 have been reported, predominantly affecting male patients and active Covid-19 cases.

IMMUNOGENETICS (2022)

Article Multidisciplinary Sciences

Algorithm for sample availability prediction in a hospital-based epidemiological study spreadsheet-based sample availability calculator

Amrit Sudershan, Kanak Mahajan, Rakesh K. Panjaliya, Manoj K. Dhar, Parvinder Kumar

Summary: Sampling methods for studying population behavior are uncertain and require representative samples for generalization. Sample size greatly affects the detection of research effects, with smaller samples having lower statistical power and higher risk of missing underlying differences. This study provides a calculation method for determining sample availability during research.

SCIENTIFIC REPORTS (2022)

Review Clinical Neurology

Migraine as an inflammatory disorder with microglial activation as a prime candidate

Amrit Sudershan, Mohd Younis, Srishty Sudershan, Parvinder Kumar

Summary: This article reviews the various aspects of microglial activation signaling pathways to elucidate the correlation between microglial involvement and the progression of migraine conditions.

NEUROLOGICAL RESEARCH (2023)

Article Clinical Neurology

An Association Study of ESR1-XbaI and PvuII Gene Polymorphism in Migraine Susceptibility in the Jammu Region

Sawan Kumar, Jyotdeep Kour Raina, Amrit Sudershan, Kanak Mahajan, Raman Jasrotia, Chinmoyee Maharana, Rakesh K. K. Panjalia, Parvinder Kumar

Summary: This study focuses on the association of ESR1 gene polymorphisms (PvuII and XbaI) with migraine. The results show a significant association between ESR-XbaI polymorphism and migraine, including both subtypes: migraine with aura and migraine without aura. This study highlights the importance of multiple environmental and genetic factors in understanding the complexity of migraine.

EUROPEAN NEUROLOGY (2023)

Article Clinical Neurology

Enlightening the association between TNF-alpha-308 G > A and migraine: a meta-analysis with meta-regression and trial sequential analysis

Amrit Sudershan, Srishty Sudershan, Mohd Younis, Meenakshi Bhagat, Agar Chander Pushap, Hardeep Kumar, Parvinder Kumar

Summary: This meta-analysis found that the TNF-alpha 308G > A mutation is associated with an increased risk of migraine only in the Asian population.

BMC NEUROLOGY (2023)

Article Biochemistry & Molecular Biology

A Comprehensive Investigation into the Association Between Mthfr C677t, A1298c, and Ace I/D Variants and Risk of Migraine: an Updated Meta-Analysis of Genetic Association Studies with Trial Sequential Analysis and Meta-Regression

Amrit Sudershan, Agar Chander Pushap, Hardeep Kumar, Parvinder Kumar

Summary: The present meta-analysis found that MTHFR-C677T is significantly associated with an increased risk of migraine and its clinical subtype. ACE I/D also significantly increases the risk of overall migraine and both clinical subtypes. MTHFR A1289C only increases the risk of migraine in certain genetic models.

JOURNAL OF MOLECULAR NEUROSCIENCE (2023)

Article Biochemistry & Molecular Biology

A Comprehensive Investigation of Risk Association Between the-786 T > C,+884 G > A, VNTR, rs743506, rs3918226 of eNOS and Susceptibility of Migraine: A Updated Meta-Analysis Utilizing Trial Sequential Analysis

Amrit Sudershan, Meenakshi Bhagat, Kuljeet Singh, Agar Chander Pushap, Hardeep Kumar, Parvinder Kumar

Summary: Migraine is a complex neurovascular disorder with multiple genes influencing pain threshold susceptibility. This meta-analysis aimed to investigate the association between eNOS gene variants and the risk of migraine and its clinical subtypes. The results showed a significant protective association between rs743506 and migraine, while rs1799983 and rs3918226 were found to be significantly associated with the risk of migraine with aura. Further studies are needed to establish the risk.

JOURNAL OF MOLECULAR NEUROSCIENCE (2023)

Article Cell Biology

Genetic association study of ACE I/D, 4a/b of eNOS, rs1801133 of MTHFR, and T344C of CYP11B2 with chronic kidney disease (CKD) in the Jammu region of North Indian population

Meenakshi Bhagat, Jyotdeep Kour Raina, Minakashee Sharma, Amrit Sudershan, Kanak Mahajan, Isha Sharma, Rakesh K. Panjalia, Parvinder Kumar

Summary: This study examines the association between genetic polymorphisms (ACE I/D, eNOS 4a/b, MTHFR rs1801133, and CYP11B2 T344C) and chronic kidney diseases (CKD) in the population of Jammu region. The results show a significant correlation between these genetic variations and the risk of CKD.

NUCLEUS-INDIA (2023)

Article Cell Biology

Genetic association study of rs1801133 of MTHFR, rs4646903 of CYP1A1, null mutation of GSTM1&GSTT1 with leukemia in the Jammu region of north Indian population

Sushma Devi, Jyotdeep Kour Raina, Pawan Kumar, Amrit Sudershan, Ravi Sharma, Rakesh K. Panjalyia, Sanjeev K. Digra, Parvinder Kumar

Summary: This study investigated the frequency and association of specific genetic variations with the risk of leukemia in the Jammu region of north Indian population. The results showed that rs1801133 of MTHFR, rs4646903 of CYP1A1, and GSTT1-null mutation were significantly associated with leukemia risk.

NUCLEUS-INDIA (2023)

No Data Available